Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study by Satoshi Yoshiji, Satoshi Yoshiji, Satoshi Yoshiji, Satoshi Yoshiji, Satoshi Yoshiji, Daisuke Tanaka, Hiroto Minamino, Hiroto Minamino, Tianyuan Lu, Tianyuan Lu, Guillaume Butler-Laporte, Guillaume Butler-Laporte, Takaaki Murakami, Yoshihito Fujita, J. Brent Richards, J. Brent Richards, J. Brent Richards, J. Brent Richards, J. Brent Richards, Nobuya Inagaki

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Capturing additional genetic risk from family history for improved polygenic risk prediction by Tianyuan Lu, Vincenzo Forgetta, J. Brent Richards, Celia M. T. Greenwood

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An efficient paradigm for genetic epidemiology cohort creation. by Martin Ladouceur, William D Leslie, Zari Dastani, David Goltzman, J Brent Richards

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Multiple regression methods show great potential for rare variant association tests. by ChangJiang Xu, Martin Ladouceur, Zari Dastani, J Brent Richards, Antonio Ciampi, Celia M T Greenwood

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Performance of genotype imputation for low frequency and rare variants from the 1000 genomes. by Hou-Feng Zheng, Jing-Jing Rong, Ming Liu, Fang Han, Xing-Wei Zhang, J Brent Richards, Li Wang

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Alternative splicing in lung influences COVID-19 severity and respiratory diseases by Tomoko Nakanishi, Julian Willett, Yossi Farjoun, Richard J. Allen, Beatriz Guillen-Guio, Darin Adra, Sirui Zhou, J. Brent Richards

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Little evidence for an effect of smoking on multiple sclerosis risk: A Mendelian Randomization study. by Ruth E Mitchell, Kirsty Bates, Robyn E Wootton, Adil Harroud, J Brent Richards, George Davey Smith, Marcus R Munafò

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Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study. by Despoina Manousaki, Adil Harroud, Ruth E Mitchell, Stephanie Ross, Vince Forgetta, Nicholas J Timpson, George Davey Smith, Constantin Polychronakos, J Brent Richards

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Genetic interactions affecting human gene expression identified by variance association mapping by Andrew Anand Brown, Alfonso Buil, Ana Viñuela, Tuuli Lappalainen, Hou-Feng Zheng, J Brent Richards, Kerrin S Small, Timothy D Spector, Emmanouil T Dermitzakis, Richard Durbin

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Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study. by Lauren E Mokry, Stephanie Ross, Omar S Ahmad, Vincenzo Forgetta, George Davey Smith, David Goltzman, Aaron Leong, Celia M T Greenwood, George Thanassoulis, J Brent Richards

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Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study by Michael Hultström, Miklos Lipcsey, Dave R. Morrison, Tomoko Nakanishi, Guillaume Butler-Laporte, Yiheng Chen, Satoshi Yoshiji, Vincenzo Forgetta, Yossi Farjoun, Ewa Wallin, Ing-Marie Larsson, Anders Larsson, Adriana Marton, Jens Marc Titze, Sandra Nihlén, J. Brent Richards, Robert Frithiof

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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i... by Andrew R Wood, John R B Perry, Toshiko Tanaka, Dena G Hernandez, Hou-Feng Zheng, David Melzer, J Raphael Gibbs, Michael A Nalls, Michael N Weedon, Tim D Spector, J Brent Richards, Stefania Bandinelli, Luigi Ferrucci, Andrew B Singleton, Timothy M Frayling

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ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 by Maik Pietzner, Robert Lorenz Chua, Eleanor Wheeler, Katharina Jechow, Julian D. S. Willett, Helena Radbruch, Saskia Trump, Bettina Heidecker, Hugo Zeberg, Frank L. Heppner, Roland Eils, Marcus A. Mall, J. Brent Richards, Leif-Erik Sander, Irina Lehmann, Sören Lukassen, Nicholas J. Wareham, Christian Conrad, Claudia Langenberg

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Improved prediction of fracture risk leveraging a genome-wide polygenic risk score by Tianyuan Lu, Vincenzo Forgetta, Julyan Keller-Baruch, Maria Nethander, Derrick Bennett, Marie Forest, Sahir Bhatnagar, Robin G. Walters, Kuang Lin, Zhengming Chen, Liming Li, Magnus Karlsson, Dan Mellström, Eric Orwoll, Eugene V. McCloskey, John A. Kanis, William D. Leslie, Robert J. Clarke, Claes Ohlsson, Celia M. T. Greenwood, J. Brent Richards

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The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. by Josine L Min, Jennifer M Taylor, J Brent Richards, Tim Watts, Fredrik H Pettersson, John Broxholme, Kourosh R Ahmadi, Gabriela L Surdulescu, Ernesto Lowy, Christian Gieger, Chris Newton-Cheh, Markus Perola, Nicole Soranzo, Ida Surakka, Cecilia M Lindgren, Jiannis Ragoussis, Andrew P Morris, Lon R Cardon, Tim D Spector, Krina T Zondervan

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RSPO3 is important for trabecular bone and fracture risk in mice and humans by Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, Thomas Levin Andersen, Charlotte Ejersted, Jianyao Wu, Karin L. Gustafsson, Antti Koskela, Juha Tuukkanen, Pedro P. C. Souza, Jan Tuckermann, Mattias Lorentzon, Linda Engström Ruud, Terho Lehtimäki, Jon H. Tobias, Sirui Zhou, Ulf H. Lerner, J. Brent Richards, Sofia Movérare-Skrtic, Claes Ohlsson

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HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases by Guillaume Butler-Laporte, Joseph Farjoun, Tomoko Nakanishi, Tianyuan Lu, Erik Abner, Yiheng Chen, Michael Hultström, Andres Metspalu, Lili Milani, Reedik Mägi, Mari Nelis, Georgi Hudjashov, Estonian Biobank Research Team, Satoshi Yoshiji, Yann Ilboudo, Kevin Y. H. Liang, Chen-Yang Su, Julian D. S. Willet, Tõnu Esko, Sirui Zhou, Vincenzo Forgetta, Daniel Taliun, J. Brent Richards

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The Biobanque québécoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories. by Karine Tremblay, Simon Rousseau, Ma'n H Zawati, Daniel Auld, Michaël Chassé, Daniel Coderre, Emilia Liana Falcone, Nicolas Gauthier, Nathalie Grandvaux, François Gros-Louis, Carole Jabet, Yann Joly, Daniel E Kaufmann, Catherine Laprise, Catherine Larochelle, François Maltais, Anne-Marie Mes-Masson, Alexandre Montpetit, Alain Piché, J Brent Richards, Sze Man Tse, Alexis F Turgeon, Gustavo Turecki, Donald C Vinh, Han Ting Wang, Vincent Mooser, BQC19

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Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. by Carolina Medina-Gomez, John P Kemp, Karol Estrada, Joel Eriksson, Jeff Liu, Sjur Reppe, David M Evans, Denise H M Heppe, Liesbeth Vandenput, Lizbeth Herrera, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, M Carola Zillikens, Ole K Olstad, Hou-Feng Zheng, J Brent Richards, Beate St Pourcain, Albert Hofman, Vincent W V Jaddoe, George Davey Smith, Mattias Lorentzon, Kaare M Gautvik, André G Uitterlinden, Robert Brommage, Claes Ohlsson, Jonathan H Tobias, Fernando Rivadeneira

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An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. by Yi-Hsiang Hsu, M Carola Zillikens, Scott G Wilson, Charles R Farber, Serkalem Demissie, Nicole Soranzo, Estelle N Bianchi, Elin Grundberg, Liming Liang, J Brent Richards, Karol Estrada, Yanhua Zhou, Atila van Nas, Miriam F Moffatt, Guangju Zhai, Albert Hofman, Joyce B van Meurs, Huibert A P Pols, Roger I Price, Olle Nilsson, Tomi Pastinen, L Adrienne Cupples, Aldons J Lusis, Eric E Schadt, Serge Ferrari, André G Uitterlinden, Fernando Rivadeneira, Timothy D Spector, David Karasik, Douglas P Kiel

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