Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) by Andrea Jantsch, Lidia Nieto, Jürg Gertsch, Javier Rodríguez-Salarichs, Ruth Matesanz, Jesús Jiménez-Barbero, J. Fernando Díaz, Ángeles Canales, Karl-Heinz Altmann

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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin by Grégory Menchon, Andrea E. Prota, Daniel Lucena-Agell, Pascal Bucher, Rolf Jansen, Herbert Irschik, Rolf Müller, Ian Paterson, J. Fernando Díaz, Karl-Heinz Altmann, Michel O. Steinmetz

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Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B Cells by Jessica Nayelli Sánchez-Carranza, Mariano Redondo-Horcajo, Isabel Barasoain, Ever Angel Escobar-Aguilar, César Millán-Pacheco, Laura Alvarez, Enrique Salas Vidal, J. Fernando Diaz, Leticia Gonzalez-Maya

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Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity by Cristina Gallego-Páramo, Cristina Gallego-Páramo, Noelia Hernández-Ortiz, Rubén M. Buey, Palma Rico-Lastres, Palma Rico-Lastres, Guadalupe García, Guadalupe García, J. Fernando Díaz, Pedro García, Pedro García, Margarita Menéndez, Margarita Menéndez

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Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells by Chiara Trigili, Isabel Barasoain, Pedro A. Sánchez-Murcia, Katja Bargsten, Mariano Redondo-Horcajo, Aurora Nogales, Nicola M. Gardner, Arndt Meyer, Guy J. Naylor, Elena Gómez-Rubio, Federico Gago, Michel O. Steinmetz, Ian Paterson, Andrea E. Prota, J. Fernando Díaz

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Structural insight into the stabilization of microtubules by taxanes by Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz

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Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands by Francisco de Asís Balaguer, Tobias Mühlethaler, Juan Estévez-Gallego, Enrique Calvo, Juan Francisco Giménez-Abián, April L. Risinger, Erik J. Sorensen, Christopher D. Vanderwal, Karl-Heinz Altmann, Susan L. Mooberry, Michel O. Steinmetz, María Ángela Oliva, Andrea E. Prota, J. Fernando Díaz

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Structural model for differential cap maturation at growing microtubule ends by Juan Estévez-Gallego, Fernando Josa-Prado, Siou Ku, Ruben M Buey, Francisco A Balaguer, Andrea E Prota, Daniel Lucena-Agell, Christina Kamma-Lorger, Toshiki Yagi, Hiroyuki Iwamoto, Laurence Duchesne, Isabel Barasoain, Michel O Steinmetz, Denis Chrétien, Shinji Kamimura, J Fernando Díaz, Maria A Oliva

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Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells by Lauralie Peronne, Eric Denarier, Ankit Rai, Renaud Prudent, Audrey Vernet, Peggy Suzanne, Sacnicté Ramirez-Rios, Sophie Michallet, Mélanie Guidetti, Julien Vollaire, Daniel Lucena-Agell, Anne-Sophie Ribba, Véronique Josserand, Jean-Luc Coll, Patrick Dallemagne, J. Fernando Díaz, María Ángela Oliva, Karin Sadoul, Anna Akhmanova, Annie Andrieux, Laurence Lafanechère

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