PI-05: PHARMACODYNAMIC EFFECTS OF AG-946, A HIGHLY POTENT NOVEL ACTIVATOR OF PYRUVATE KINASE, IN EX VIVO TREATMENT OF RED BLOOD CELLS FROM SICKLE CELL DISEASE PATIENTS by RAB M., VAN DIJK M., BOS J., VAN OIRSCHOT B., GERRITS J., KOSINSKI P., KUNG C., JANS J., VAN BEERS E., DANG L., VAN WIJK R.

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PI-02: FOLLOW-UP RESULTS OF A PHASE 2 STUDY ASSESSING THE SAFETY AND EFFICACY OF MITAPIVAT TREATMENT, AN ORAL PYRUVATE KINASE ACTIVATOR, FOR UP TO 60 WEEKS IN SUBJECTS WITH SICKLE... by VAN DIJK M., RAB M., VAN OIRSCHOT B., BOS J., DERICHS C., RIJNEVELD A., CNOSSEN M., NUR E., BIEMOND B., BARTELS M., JANS J., VAN SOLINGE W., SCHUTGENS R., VAN WIJK R., VAN BEERS E.

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P-023: 2,3-DIPHOSPHOGLYCERATE DETECTION VIA DIRECT INFUSION HIGH RESOLUTION MASS SPECTROMETRY CORRELATES WITH QUANTITATIVE DETECTION IN BLOOD OF PATIENTS WITH SICKLE CELL DISEASE by VAN DER VEEN S., VAN DIJK M., JANS J., VERHOEVEN-DUIF N., VAN WIJK R., BARTELS M., MAÑÚ PEREIRA M., COLOMBATTI R., MARTELLA M., MUNARETO V., BOARO M., BARTOLLUCI P., CNOSSEN M., BIEMOND B., VAN BEERS E.

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