Early Microbes Modify Immune System Development and Metabolic Homeostasis—The “Restaurant” Hypothesis Revisited by Michael J. Nash, Daniel N. Frank, Jacob E. Friedman, Jacob E. Friedman

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Imbalance in gut microbes from babies born to obese mothers increases gut permeability and myeloid cell adaptations that provoke obesity and NAFLD by Taylor K. Soderborg, Jacob E. Friedman

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Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis by Shaikh Mizanoor Rahman, Ishtiaq Qadri, Rachel C. Janssen, Jacob E. Friedman

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Preferences for heat, cold, or contrast in patients with knee osteoarthritis affect treatment response by Craig R Denegar, Devon R Dougherty, Jacob E Friedman, et al

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A maternal higher-complex carbohydrate diet increases bifidobacteria and alters early life acquisition of the infant microbiome in women with gestational diabetes mellitus by Kameron Y. Sugino, Teri L. Hernandez, Teri L. Hernandez, Linda A. Barbour, Linda A. Barbour, Jennifer M. Kofonow, Daniel N. Frank, Jacob E. Friedman, Jacob E. Friedman

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Pediatric Non-Alcoholic Fatty Liver Disease: Nutritional Origins and Potential Molecular Mechanisms by Ashok Mandala, Rachel C. Janssen, Sirish Palle, Kevin R. Short, Jacob E. Friedman

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Islet autoantibody seroconversion in type-1 diabetes is associated with metagenome-assembled genomes in infant gut microbiomes by Li Zhang, Karen R. Jonscher, Zuyuan Zhang, Yi Xiong, Ryan S. Mueller, Jacob E. Friedman, Chongle Pan

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Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques. by Wilmon F Grant, Lindsey E Nicol, Stephanie R Thorn, Kevin L Grove, Jacob E Friedman, Daniel L Marks

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Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD by Ashok Mandala, Evgenia Dobrinskikh, Rachel C. Janssen, Oliver Fiehn, Angelo D’Alessandro, Jacob E. Friedman, Karen R. Jonscher

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Isolating mononuclear cells from fetal bone and liver for metabolic, functional, and immunophenotypic analyses in nonhuman primates by Michael J. Nash, Evgenia Dobrinskikh, Dong Wang, Eric M. Pietras, Rachel C. Janssen, Jacob E. Friedman, Stephanie R. Wesolowski

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Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding. by Brittany V Martin-Murphy, Qiang You, Hong Wang, Becky A De La Houssaye, Timothy P Reilly, Jacob E Friedman, Cynthia Ju

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Gestational Diabetes Is Uniquely Associated With Altered Early Seeding of the Infant Gut Microbiota by Taylor K. Soderborg, Charles M. Carpenter, Rachel C. Janssen, Tiffany L. Weir, Charles E. Robertson, Diana Ir, Bridget E. Young, Nancy F. Krebs, Teri L. Hernandez, Teri L. Hernandez, Linda A. Barbour, Linda A. Barbour, Daniel N. Frank, Miranda Kroehl, Jacob E. Friedman, Jacob E. Friedman

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Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver by Kameron Y. Sugino, Ashok Mandala, Rachel C. Janssen, Sunam Gurung, MaJoi Trammell, Michael W. Day, Richard S. Brush, James F. Papin, David W. Dyer, Martin-Paul Agbaga, Martin-Paul Agbaga, Jacob E. Friedman, Jacob E. Friedman, Marisol Castillo-Castrejon, Marisol Castillo-Castrejon, Karen R. Jonscher, Karen R. Jonscher, Dean A. Myers

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Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic SteatohepatitisSummary by David J. Matye, Huaiwen Wang, Wenyi Luo, Rachel R. Sharp, Cheng Chen, Lijie Gu, Kenneth L. Jones, Wen-Xing Ding, Jacob E. Friedman, Tiangang Li

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Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle. by Kristen E Boyle, Hyonson Hwang, Rachel C Janssen, James M DeVente, Linda A Barbour, Teri L Hernandez, Lawrence J Mandarino, Martha Lappas, Jacob E Friedman

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Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates. by Wilmon F Grant, Melanie B Gillingham, Ayesha K Batra, Natasha M Fewkes, Sarah M Comstock, Diana Takahashi, Theodore P Braun, Kevin L Grove, Jacob E Friedman, Daniel L Marks

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Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring by Michael J. Nash, Evgenia Dobrinskikh, Sean A. Newsom, Ilhem Messaoudi, Rachel C. Janssen, Kjersti M. Aagaard, Carrie E. McCurdy, Maureen Gannon, Paul Kievit, Jacob E. Friedman, Stephanie R. Wesolowski

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Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project. by Allison L B Shapiro, Kristen E Boyle, Dana Dabelea, Zachary W Patinkin, Becky De la Houssaye, Brandy M Ringham, Deborah H Glueck, Linda A Barbour, Jill M Norris, Jacob E Friedman

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TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis by David Matye, Sumedha Gunewardena, Jianglei Chen, Huaiwen Wang, Yifeng Wang, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Yanhong Du, Cheng Chen, Jacob E. Friedman, Shelly C. Lu, Wen-Xing Ding, Tiangang Li

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Spaceflight Activates Lipotoxic Pathways in Mouse Liver. by Karen R Jonscher, Alba Alfonso-Garcia, Jeffrey L Suhalim, David J Orlicky, Eric O Potma, Virginia L Ferguson, Mary L Bouxsein, Ted A Bateman, Louis S Stodieck, Moshe Levi, Jacob E Friedman, Daila S Gridley, Michael J Pecaut

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