Digital Brain Maps and Virtual Neuroscience: An Emerging Role for Light-Sheet Fluorescence Microscopy in Drug Development by Johanna Perens, Jacob Hecksher-Sørensen

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Whole-brain three-dimensional imaging for quantification of drug targets and treatment effects in mouse models of neurodegenerative diseases by Henrik H Hansen, Urmas Roostalu, Jacob Hecksher-Sørensen

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Double Labeling for Whole-Mount In Situ Hybridization in Mouse by Jacob Hecksher-Sørensen, Robert E. Hill, Laura Lettice

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Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation. by Thomas Frogne, Kathrine Beck Sylvestersen, Stefan Kubicek, Michael Lund Nielsen, Jacob Hecksher-Sørensen

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3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II by Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Thomas Klein, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen

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Deep learning reveals 3D atherosclerotic plaque distribution and composition by Vanessa Isabell Jurtz, Grethe Skovbjerg, Casper Gravesen Salinas, Urmas Roostalu, Louise Pedersen, Jacob Hecksher-Sørensen, Bidda Rolin, Michael Nyberg, Martijn van de Bunt, Camilla Ingvorsen

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Atlas of exercise-induced brain activation in mice by Grethe Skovbjerg, Andreas Mæchel Fritzen, Charlotte Sashi Aier Svendsen, Johanna Perens, Jacob Lercke Skytte, Camilla Lund, Jens Lund, Martin Rønn Madsen, Urmas Roostalu, Jacob Hecksher-Sørensen, Christoffer Clemmensen

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Whole-brain activation signatures of weight-lowering drugs by Henrik H. Hansen, Johanna Perens, Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Pernille Barkholt, Ditte Dencker Thorbek, Kristoffer T.G. Rigbolt, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen

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TAAR1 agonists improve glycemic control, reduce body weight and modulate neurocircuits governing energy balance and feeding by Nina Dedic, Lien Wang, Eva Hajos-Korcsok, Jacob Hecksher-Sørensen, Urmas Roostalu, Steven P. Vickers, Serena Wu, Christoph Anacker, Colleen Synan, Philip G. Jones, Snezana Milanovic, Seth C. Hopkins, Linda J. Bristow, Kenneth S. Koblan

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Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography by Urmas Roostalu, Louise Thisted, Jacob Lercke Skytte, Casper Gravesen Salinas, Philip Juhl Pedersen, Jacob Hecksher-Sørensen, Bidda Rolin, Henrik H. Hansen, James G. MacKrell, Robert M. Christie, Niels Vrang, Jacob Jelsing, Nora Elisabeth Zois

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Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease by Urmas Roostalu, Casper B. G. Salinas, Ditte D. Thorbek, Jacob L. Skytte, Katrine Fabricius, Pernille Barkholt, Linu M. John, Vanessa Isabell Jurtz, Lotte Bjerre Knudsen, Jacob Jelsing, Niels Vrang, Henrik H. Hansen, Jacob Hecksher-Sørensen

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The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE−/− and LDLr−/− Mice by a Mechanism That Includes Inflammatory Pathways by Günaj Rakipovski, PhD, Bidda Rolin, DVM, Jane Nøhr, PhD, Ib Klewe, PhD, Klaus S. Frederiksen, PhD, Robert Augustin, PhD, Jacob Hecksher-Sørensen, PhD, Camilla Ingvorsen, PhD, Joseph Polex-Wolf, PhD, Lotte Bjerre Knudsen, DMSc

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An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation by Tamara Casteels, Yufeng Zhang, Thomas Frogne, Caterina Sturtzel, Charles-Hugues Lardeau, Ilke Sen, Xiaocheng Liu, Shangyu Hong, Florian M. Pauler, Thomas Penz, Marlene Brandstetter, Charlotte Barbieux, Ekaterine Berishvili, Thomas Heuser, Christoph Bock, Christian G. Riedel, Dirk Meyer, Martin Distel, Jacob Hecksher-Sørensen, Jin Li, Stefan Kubicek

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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergisti... by Brandon B. Boland, Rhianna C. Laker, Siobhan O'Brien, Sadichha Sitaula, Isabelle Sermadiras, Jens Christian Nielsen, Pernille Barkholt, Urmas Roostalu, Jacob Hecksher-Sørensen, Sara Rubek Sejthen, Ditte Dencker Thorbek, Arthur Suckow, Nicole Burmeister, Stephanie Oldham, Sarah Will, Victor G. Howard, Benji M. Gill, Philip Newton, Jacqueline Naylor, David C. Hornigold, Jotham Austin, Louise Lantier, Owen P. McGuinness, James L. Trevaskis, Joseph S. Grimsby, Christopher J. Rhodes

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The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates by Violeta Georgieva Tsonkova, Fredrik Wolfhagen Sand, Xenia Asbæk Wolf, Lars Groth Grunnet, Anna Kirstine Ringgaard, Camilla Ingvorsen, Louise Winkel, Mark Kalisz, Kevin Dalgaard, Christine Bruun, Johannes Josef Fels, Charlotte Helgstrand, Sven Hastrup, Fredrik Kryh Öberg, Erik Vernet, Michael Paolo Bastner Sandrini, Allan Christian Shaw, Carsten Jessen, Mads Grønborg, Jacob Hald, Hanni Willenbrock, Dennis Madsen, Rasmus Wernersson, Lena Hansson, Jan Nygaard Jensen, Annette Plesner, Tomas Alanentalo, Maja Borup Kjær Petersen, Anne Grapin-Botton, Christian Honoré, Jonas Ahnfelt-Rønne, Jacob Hecksher-Sørensen, Philippe Ravassard, Ole D. Madsen, Claude Rescan, Thomas Frogne

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