Origins of ETP Leukemia by Booth, CAG, Jacobsen, SEW, Mead, AJ

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors by Neo, WH, Meng, Y, Rodriguez-Meira, A, Fadlullah, MZH, Booth, CAG, Azzoni, E, Thongjuea, S, de Bruijn, MFTR, Jacobsen, SEW, Mead, AJ, Lacaud, G

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells by Matsuoka, S, Facchini, R, Luis, TC, Carrelha, J, Woll, PS, Mizukami, T, Wu, B, Boukarabila, H, Buono, M, Norfo, R, Arai, F, Suda, T, Mead, AJ, Nerlov, C, Jacobsen, SEW

The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition by Azzoni, E, Frontera, V, Anselmi, G, Rode, C, James, C, Deltcheva, EM, Demian, AS, Brown, J, Barone, C, Patelli, A, Harman, JR, Nicholls, M, Conway, SJ, Morrissey, E, Jacobsen, SEW, Sparrow, DB, Harris, AL, Enver, T, de Bruijn, MFTR

Ezh2 and Runx1 mutations collaborate to initiate lympho-myeloid leukemia in early thymic progenitors by Booth, CAG, Barkas, N, Neo, WH, Boukarabila, H, Soilleux, EJ, Giotopoulos, G, Farnoud, N, Giustacchini, A, Ashley, N, Carrelha, J, Jamieson, L, Atkinson, D, Bouriez-Jones, T, Prinjha, RK, Milne, TA, Teachey, DT, Papaemmanuil, E, Huntly, BJP, Jacobsen, SEW, Mead, AJ

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner by Luis, TC, Barkas, N, Carrelha, J, Giustacchini, A, Mazzi, S, Norfo, R, Wu, B, Aliouat, A, Guerrero, JA, Rodriguez-Meira, A, Bouriez-Jones, T, Macaulay, IC, Jasztal, M, Zhu, G, Ni, H, Robson, MJ, Blakely, RD, Mead, AJ, Nerlov, C, Ghevaert, C, Jacobsen, SEW

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution by Rodriguez-Meira, A, Norfo, R, Wen, S, Chédeville, AL, Rahman, H, O'Sullivan, J, Wang, G, Louka, E, Kretzschmar, WW, Paterson, A, Brierley, C, Martin, J-E, Demeule, C, Bashton, M, Sousos, N, Moralli, D, Subha Meem, L, Carrelha, J, Wu, B, Hamblin, A, Guermouche, H, Pasquier, F, Marzac, C, Girodon, F, Vainchenker, W, Drummond, M, Harrison, C, Chapman, JR, Plo, I, Jacobsen, SEW, Psaila, B, Thongjuea, S, Antony-Debré, I, Mead, AJ

Integrative genomics identifies the molecular basis of resistance to azacitidine therapy in myelodysplastic syndromes by Unnikrishnan, A, Deshpande, NP, Verma, A, Kumari, A, Richards, LA, Knezevic, K, Chandrakanthan, V, Thoms, JAI, Tursky, ML, Huang, Y, Ali, Z, Olivier, J, Galbraith, S, Kulasekararaj, AG, Tobiasson, M, Karimi, M, Pellagatti, A, Wilson, SR, Lindeman, R, Young, B, Ramakrishna, R, Arthur, C, Stark, R, Crispin, P, Curnow, J, Warburton, P, Roncolato, F, Boultwood, J, Lynch, K, Jacobsen, SEW, Mufti, GJ, Hellstrom-Lindberg, E, Wilkins, MR, MacKenzie, KL, Wong, JWH, Campbell, PJ, Pimanda, JE