561 Targeting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy by Nir Hacohen, Soldano Ferrone, Keith Flaherty, Tatyana Sharova, Genevieve M Boland, Robert T Manguso, Payal Tiwari, Debattama R Sen, Arnav Mehta, William Michaud, Or-Yam Revach, Angelina Cicerchia, Moshe Sade-Feldman, Seth Anderson, Boryana Petrova, Ofir Shorer, Lloyd Bod, Giulia Cattaneo, Hongyan Xie, Martin Rasmussen, Jacy Fang, Keren Yizhak, Naama Kanarek, Russell Jenkins