Mining folded proteomes in the era of accurate structure prediction. by Charles Bayly-Jones, James C Whisstock

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Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector by Charles Bayly-Jones, Charles Bayly-Jones, Siew Siew Pang, Siew Siew Pang, Bradley A. Spicer, Bradley A. Spicer, James C. Whisstock, James C. Whisstock, James C. Whisstock, Michelle A. Dunstone, Michelle A. Dunstone

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A new model for pore formation by cholesterol-dependent cytolysins. by Cyril F Reboul, James C Whisstock, Michelle A Dunstone

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The AprV5 subtilase is required for the optimal processing of all three extracellular serine proteases from Dichelobacter nodosus. by Xiaoyan Han, Ruth M Kennan, David L Steer, A Ian Smith, James C Whisstock, Julian I Rood

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A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen by Adam J. Quek, Nathan P. Cowieson, Tom T. Caradoc-Davies, Paul J. Conroy, James C. Whisstock, Ruby H. P. Law

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PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy by Sergey Gorelick, Genevieve Buckley, Gediminas Gervinskas, Travis K Johnson, Ava Handley, Monica Pia Caggiano, James C Whisstock, Roger Pocock, Alex de Marco

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MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography. by Arun S Konagurthu, Cyril F Reboul, Jason W Schmidberger, James A Irving, Arthur M Lesk, Peter J Stuckey, James C Whisstock, Ashley M Buckle

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Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. by Marcin Poreba, Sheena McGowan, Tina S Skinner-Adams, Katharine R Trenholme, Donald L Gardiner, James C Whisstock, Joyce To, Guy S Salvesen, John P Dalton, Marcin Drag

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Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor by Charles Bayly-Jones, Christopher J. Lupton, Claudia Fritz, Hariprasad Venugopal, Daniel Ramsbeck, Michael Wermann, Christian Jäger, Alex de Marco, Stephan Schilling, Dagmar Schlenzig, James C. Whisstock

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The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions. by Christopher G Langendorf, Trevor L G Key, Gustavo Fenalti, Wan-Ting Kan, Ashley M Buckle, Tom Caradoc-Davies, Kellie L Tuck, Ruby H P Law, James C Whisstock

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Parsing the IL-37-Mediated Suppression of Inflammasome Function by Ina Rudloff, Holly K. Ung, Jennifer K. Dowling, Ashley Mansell, Laura D’Andrea, Andrew M. Ellisdon, James C. Whisstock, Philip J. Berger, Claudia A. Nold-Petry, Marcel F. Nold

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Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase. by Amanda J Cork, Daniel J Ericsson, Ruby H P Law, Lachlan W Casey, Eugene Valkov, Carlo Bertozzi, Anna Stamp, Blagojce Jovcevski, J Andrew Aquilina, James C Whisstock, Mark J Walker, Bostjan Kobe

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The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9 by Charles Bayly-Jones, Bill H. T. Ho, Corinna Lau, Eleanor W. W. Leung, Laura D’Andrea, Christopher J. Lupton, Susan M. Ekkel, Hariprasad Venugopal, James C. Whisstock, Tom E. Mollnes, Bradley A. Spicer, Michelle A. Dunstone

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RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. by Jennifer C Y Lo, Duangporn Jamsai, Anne E O'Connor, Claire Borg, Brett J Clark, James C Whisstock, Mark C Field, Vicki Adams, Tomomoto Ishikawa, R John Aitken, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Moira K O'Bryan

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The X-ray Crystal Structure of Full-Length Human Plasminogen by Ruby H.P. Law, Tom Caradoc-Davies, Nathan Cowieson, Anita J. Horvath, Adam J. Quek, Joanna Amarante Encarnacao, David Steer, Angus Cowan, Qingwei Zhang, Bernadine G.C. Lu, Robert N. Pike, A. Ian Smith, Paul B. Coughlin, James C. Whisstock

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Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice by Annie S.P. Yang, Matthew T. O’Neill, Charlie Jennison, Sash Lopaticki, Cody C. Allison, Jennifer S. Armistead, Sara M. Erickson, Kelly L. Rogers, Andrew M. Ellisdon, James C. Whisstock, Rebecca E. Tweedell, Rhoel R. Dinglasan, Donna N. Douglas, Norman M. Kneteman, Justin A. Boddey

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The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65. by Hayley J Newton, Jaclyn S Pearson, Luminita Badea, Michelle Kelly, Mark Lucas, Gavan Holloway, Kylie M Wagstaff, Michelle A Dunstone, Joan Sloan, James C Whisstock, James B Kaper, Roy M Robins-Browne, David A Jans, Gad Frankel, Alan D Phillips, Barbara S Coulson, Elizabeth L Hartland

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The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1 by Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A. Spicer, Ruby H. P. Law, Adrian W. Hodel, Edward S. Parsons, Susan M. Ekkel, Paul J. Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I. Bird, Bart W. Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A. Dunstone, James C. Whisstock

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Conformational changes during pore formation by the perforin-related protein pleurotolysin. by Natalya Lukoyanova, Stephanie C Kondos, Irene Farabella, Ruby H P Law, Cyril F Reboul, Tom T Caradoc-Davies, Bradley A Spicer, Oded Kleifeld, Daouda A K Traore, Susan M Ekkel, Ilia Voskoboinik, Joseph A Trapani, Tamas Hatfaludi, Katherine Oliver, Eileen M Hotze, Rodney K Tweten, James C Whisstock, Maya Topf, Helen R Saibil, Michelle A Dunstone

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Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities by Steven X. Cho, Ina Rudloff, Jason C. Lao, Merrin A. Pang, Rimma Goldberg, Christine B. Bui, Catriona A. McLean, Magdalena Stock, Tilman E. Klassert, Hortense Slevogt, Niamh E. Mangan, Wei Cheng, Doris Fischer, Stefan Gfroerer, Manjeet K. Sandhu, Devi Ngo, Alexander Bujotzek, Laurent Lariviere, Felix Schumacher, Georg Tiefenthaler, Friederike Beker, Clare Collins, C. Omar F. Kamlin, Kai König, Atul Malhotra, Kenneth Tan, Christiane Theda, Alex Veldman, Andrew M. Ellisdon, James C. Whisstock, Philip J. Berger, Claudia A. Nold-Petry, Marcel F. Nold

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