James D. Brenton

Professor James D Brenton is a clinician scientist and Senior Group Leader at the Cancer Research UK Cambridge Institute and Professor of Ovarian Cancer Medicine in the Department of Oncology, University of Cambridge. He is an Honorary Consultant in Medical Oncology at Addenbrooke's Hospital, Cambridge University Hospitals, Ovarian Cancer Domain Lead for the 100,000 Genomes Project by Genomics England, and co-founder and Clinical Advisor to Inivata Ltd, a clinical cancer genomics company. Provided by Wikipedia
Showing 1 - 20 results of 31 for search 'James D. Brenton', query time: 0.06s Refine Results
  1. 1
    SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells.

    SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells. by David A Tumbarello, Melissa R Andrews, James D Brenton

    Published 2016-01-01
    Get full text
    Article
  2. 2
    Phylogenetic quantification of intra-tumour heterogeneity.

    Phylogenetic quantification of intra-tumour heterogeneity. by Roland F Schwarz, Anne Trinh, Botond Sipos, James D Brenton, Nick Goldman, Florian Markowetz

    Published 2014-04-01
    Get full text
    Article
  3. 3
    Refined characterization of circulating tumor DNA through biological feature integration

    Refined characterization of circulating tumor DNA through biological feature integration by Havell Markus, Dineika Chandrananda, Elizabeth Moore, Florent Mouliere, James Morris, James D. Brenton, Christopher G. Smith, Nitzan Rosenfeld

    Published 2022-02-01
    Get full text
    Article
  4. 4
    Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women.

    Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women. by Linda E Kelemen, James D Brenton, Christine Parkinson, Hayley C Whitaker, Anna M Piskorz, Ilona Csizmadi, Paula J Robson

    Published 2014-01-01
    Get full text
    Article
  5. 5
    Association between tumour infiltrating lymphocytes, histotype and clinical outcome in epithelial ovarian cancer

    Association between tumour infiltrating lymphocytes, histotype and clinical outcome in epithelial ovarian cancer by Fiona R. James, Mercedes Jiminez-Linan, Jennifer Alsop, Marie Mack, Honglin Song, James D. Brenton, Paul D. P. Pharoah, H. Raza Ali

    Published 2017-09-01
    Get full text
    Article
  6. 6
    A metadata approach for clinical data management in translational genomics studies in breast cancer

    A metadata approach for clinical data management in translational genomics studies in breast cancer by James D Brenton Irene Papatheodorou Charles Crichton Lorna Morris Peter Maccallum Molecular Taxonomy of Breast Cancer International Consortium METABRIC Group Jim Davies, Caldas, C

    Published 2009
    Conference item
  7. 7
    Lesion-specific 3D-printed moulds for image-guided tissue multi-sampling of ovarian tumours: A prospective pilot study

    Lesion-specific 3D-printed moulds for image-guided tissue multi-sampling of ovarian tumours: A prospective pilot study by Maria Delgado-Ortet, Maria Delgado-Ortet, Marika A. V. Reinius, Marika A. V. Reinius, Marika A. V. Reinius, Marika A. V. Reinius, Cathal McCague, Cathal McCague, Cathal McCague, Vlad Bura, Vlad Bura, Vlad Bura, Vlad Bura, Ramona Woitek, Ramona Woitek, Ramona Woitek, Ramona Woitek, Leonardo Rundo, Leonardo Rundo, Leonardo Rundo, Andrew B. Gill, Andrew B. Gill, Marcel Gehrung, Marcel Gehrung, Stephan Ursprung, Stephan Ursprung, Stephan Ursprung, Helen Bolton, Krishnayan Haldar, Pubudu Pathiraja, James D. Brenton, James D. Brenton, James D. Brenton, James D. Brenton, Mireia Crispin-Ortuzar, Mireia Crispin-Ortuzar, Mercedes Jimenez-Linan, Mercedes Jimenez-Linan, Lorena Escudero Sanchez, Lorena Escudero Sanchez, Evis Sala, Evis Sala, Evis Sala, Evis Sala, Evis Sala

    Published 2023-02-01
    Get full text
    Article
  8. 8
    Integrative radiogenomics for virtual biopsy and treatment monitoring in ovarian cancer

    Integrative radiogenomics for virtual biopsy and treatment monitoring in ovarian cancer by Paula Martin-Gonzalez, Mireia Crispin-Ortuzar, Leonardo Rundo, Maria Delgado-Ortet, Marika Reinius, Lucian Beer, Ramona Woitek, Stephan Ursprung, Helen Addley, James D. Brenton, Florian Markowetz, Evis Sala

    Published 2020-08-01
    Get full text
    Article
  9. 9
    scAbsolute: measuring single-cell ploidy and replication status

    scAbsolute: measuring single-cell ploidy and replication status by Michael P. Schneider, Amy E. Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Elke Van Oudenhove, Maria J. Garcia, Blas Chaves Urbano, Anna M. Piskorz, James D. Brenton, Geoff Macintyre, Florian Markowetz

    Published 2024-03-01
    Get full text
    Article
  10. 10
    Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models

    Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models by Carolin M Sauer, Katrin Heider, Jelena Belic, Samantha E Boyle, James A Hall, Dominique‐Laurent Couturier, Angela An, Aadhitthya Vijayaraghavan, Marika AV Reinius, Karen Hosking, Maria Vias, Nitzan Rosenfeld, James D Brenton

    Published 2022-08-01
    Get full text
    Article
  11. 11
    The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.

    The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors. by Kasmintan A Schrader, Bella Gorbatcheva, Janine Senz, Alireza Heravi-Moussavi, Nataliya Melnyk, Clara Salamanca, Sarah Maines-Bandiera, Susanna L Cooke, Peter Leung, James D Brenton, C Blake Gilks, John Monahan, David G Huntsman

    Published 2009-11-01
    Get full text
    Article
  12. 12
    Clinically Interpretable Radiomics-Based Prediction of Histopathologic Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma

    Clinically Interpretable Radiomics-Based Prediction of Histopathologic Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma by Leonardo Rundo, Leonardo Rundo, Lucian Beer, Lucian Beer, Lucian Beer, Lorena Escudero Sanchez, Lorena Escudero Sanchez, Mireia Crispin-Ortuzar, Mireia Crispin-Ortuzar, Mireia Crispin-Ortuzar, Marika Reinius, Marika Reinius, Marika Reinius, Cathal McCague, Cathal McCague, Hilal Sahin, Hilal Sahin, Hilal Sahin, Vlad Bura, Vlad Bura, Vlad Bura, Roxana Pintican, Roxana Pintican, Marta Zerunian, Stephan Ursprung, Iris Allajbeu, Iris Allajbeu, Helen Addley, Paula Martin-Gonzalez, Paula Martin-Gonzalez, Thomas Buddenkotte, Naveena Singh, Anju Sahdev, Ionut-Gabriel Funingana, Ionut-Gabriel Funingana, Ionut-Gabriel Funingana, Mercedes Jimenez-Linan, Mercedes Jimenez-Linan, Florian Markowetz, Florian Markowetz, James D. Brenton, James D. Brenton, James D. Brenton, Evis Sala, Evis Sala, Evis Sala, Ramona Woitek, Ramona Woitek, Ramona Woitek

    Published 2022-06-01
    Get full text
    Article
  13. 13
    High-grade serous ovarian carcinoma organoids as models of chromosomal instability

    High-grade serous ovarian carcinoma organoids as models of chromosomal instability by Maria Vias, Lena Morrill Gavarró, Carolin M Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton

    Published 2023-05-01
    Get full text
    Article
  14. 14
    Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study.

    Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective... by Christine A Parkinson, Davina Gale, Anna M Piskorz, Heather Biggs, Charlotte Hodgkin, Helen Addley, Sue Freeman, Penelope Moyle, Evis Sala, Karen Sayal, Karen Hosking, Ioannis Gounaris, Mercedes Jimenez-Linan, Helena M Earl, Wendi Qian, Nitzan Rosenfeld, James D Brenton

    Published 2016-12-01
    Get full text
    Article
  15. 15
    Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment

    Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment by Lisa J. Neilson, Douglas Cartwright, Maija Risteli, Elina M. Jokinen, Lynn McGarry, Toni Sandvik, Konstantina Nikolatou, Kelly Hodge, Samuel Atkinson, Maria Vias, Emily J. Kay, James D. Brenton, Leo M. Carlin, David M. Bryant, Tuula Salo, Sara Zanivan

    Published 2023-12-01
    Get full text
    Article
  16. 16
    Identification of Tissue-Resident Natural Killer and T Lymphocytes with Anti-Tumor Properties in Ascites of Ovarian Cancer Patients

    Identification of Tissue-Resident Natural Killer and T Lymphocytes with Anti-Tumor Properties in Ascites of Ovarian Cancer Patients by Elin Bernson, Oisín Huhn, Veronika Karlsson, Delia Hawkes, Maria Lycke, Valentina Cazzetta, Joanna Mikulak, James Hall, Anna M. Piskorz, Rosalba Portuesi, Domenico Vitobello, Barbara Fiamengo, Gabriele Siesto, Amir Horowitz, Hormas Ghadially, Domenico Mavilio, James D. Brenton, Karin Sundfeldt, Francesco Colucci

    Published 2023-06-01
    Get full text
    Article
  17. 17
    Integrated Multi-Tumor Radio-Genomic Marker of Outcomes in Patients with High Serous Ovarian Carcinoma

    Integrated Multi-Tumor Radio-Genomic Marker of Outcomes in Patients with High Serous Ovarian Carcinoma by Harini Veeraraghavan, Herbert Alberto Vargas, Alejandro Jimenez-Sanchez, Maura Micco, Eralda Mema, Yulia Lakhman, Mireia Crispin-Ortuzar, Erich P. Huang, Douglas A. Levine, Rachel N. Grisham, Nadeem Abu-Rustum, Joseph O. Deasy, Alexandra Snyder, Martin L. Miller, James D. Brenton, Evis Sala

    Published 2020-11-01
    Get full text
    Article
  18. 18
    Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.

    Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis. by Roland F Schwarz, Charlotte K Y Ng, Susanna L Cooke, Scott Newman, Jillian Temple, Anna M Piskorz, Davina Gale, Karen Sayal, Muhammed Murtaza, Peter J Baldwin, Nitzan Rosenfeld, Helena M Earl, Evis Sala, Mercedes Jimenez-Linan, Christine A Parkinson, Florian Markowetz, James D Brenton

    Published 2015-02-01
    Get full text
    Article
  19. 19
    <i>PIK3R1</i><sup>W624R</sup> Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

    <i>PIK3R1</i><sup>W624R</sup> Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma by Concetta D’Ambrosio, Jessica Erriquez, Maddalena Arigoni, Sonia Capellero, Gloria Mittica, Eleonora Ghisoni, Fulvio Borella, Dionyssios Katsaros, Silvana Privitera, Marisa Ribotta, Elena Maldi, Giovanna Di Nardo, Enrico Berrino, Tiziana Venesio, Riccardo Ponzone, Marco Vaira, Douglas Hall, Mercedes Jimenez-Linan, Anna L. Paterson, Raffaele A. Calogero, James D. Brenton, Giorgio Valabrega, Maria Flavia Di Renzo, Martina Olivero

    Published 2020-02-01
    Get full text
    Article
  20. 20
    Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

    Molecular landscape and functional characterization of centrosome amplification in ovarian cancer by Carolin M. Sauer, James A. Hall, Dominique-Laurent Couturier, Thomas Bradley, Anna M. Piskorz, Jacob Griffiths, Ashley Sawle, Matthew D. Eldridge, Philip Smith, Karen Hosking, Marika A. V. Reinius, Lena Morrill Gavarró, Anne-Marie Mes-Masson, Darren Ennis, David Millan, Aoisha Hoyle, Iain A. McNeish, Mercedes Jimenez-Linan, Filipe Correia Martins, Julia Tischer, Maria Vias, James D. Brenton

    Published 2023-10-01
    Get full text
    Article

Search Tools: