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Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. by Andrew S Bell, James E Mills, Gareth P Williams, James A Brannigan, Anthony J Wilkinson, Tanya Parkinson, Robin J Leatherbarrow, Edward W Tate, Anthony A Holder, Deborah F Smith
Published 2012-01-01
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Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation. by Michael J Thomenius, Jennifer Totman, Darren Harvey, Lorna H Mitchell, Thomas V Riera, Kat Cosmopoulos, Alexandra R Grassian, Christine Klaus, Megan Foley, Elizabeth A Admirand, Haris Jahic, Christina Majer, Tim Wigle, Suzanne L Jacques, Jodi Gureasko, Dorothy Brach, Trupti Lingaraj, Kip West, Sherri Smith, Nathalie Rioux, Nigel J Waters, Cuyue Tang, Alejandra Raimondi, Michael Munchhof, James E Mills, Scott Ribich, Margaret Porter Scott, Kevin W Kuntz, William P Janzen, Mikel Moyer, Jesse J Smith, Richard Chesworth, Robert A Copeland, P Ann Boriack-Sjodin
Published 2018-01-01
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