James Inglese

James Inglese James Inglese is an American biochemist, the [https://irp.nih.gov/pi/james-inglese director of the Assay Development and Screening Technology Laboratory] at the National Center for Advancing Translational Sciences, a Center within the National Institutes of Health. His specialty is small molecule high throughput screening. Inglese's laboratory develops methods and strategies in molecular pharmacology with drug discovery applications. The work of his research group and collaborators focuses on genetic and infectious disease-associated biology. Provided by Wikipedia
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  1. 1
    qHTSWaterfall: 3-dimensional visualization software for quantitative high-throughput screening (qHTS) data

    qHTSWaterfall: 3-dimensional visualization software for quantitative high-throughput screening (qHTS) data by Bryan Queme, John C. Braisted, Patricia Dranchak, James Inglese

    Published 2023-03-01
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  2. 2
    Differentiating Alzheimer disease-associated aggregates with small molecules

    Differentiating Alzheimer disease-associated aggregates with small molecules by Nicolette S. Honson, Ronald L. Johnson, Wenwei Huang, James Inglese, Christopher P. Austin, Jeff Kuret

    Published 2007-12-01
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  3. 3
    Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays.

    Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. by Patricia Dranchak, Ryan MacArthur, Rajarshi Guha, William J Zuercher, David H Drewry, Douglas S Auld, James Inglese

    Published 2013-01-01
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  4. 4
    In vivo quantitative high-throughput screening for drug discovery and comparative toxicology

    In vivo quantitative high-throughput screening for drug discovery and comparative toxicology by Patricia K. Dranchak, Erin Oliphant, Bryan Queme, Laurence Lamy, Yuhong Wang, Ruili Huang, Menghang Xia, Dingyin Tao, James Inglese

    Published 2023-03-01
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  5. 5
    High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells.

    High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells. by Danielle L Schmitt, Patricia Dranchak, Prakash Parajuli, Dvir Blivis, Ty Voss, Casey L Kohnhorst, Minjoung Kyoung, James Inglese, Songon An

    Published 2023-01-01
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  6. 6
    ICE1 promotes the link between splicing and nonsense-mediated mRNA decay

    ICE1 promotes the link between splicing and nonsense-mediated mRNA decay by Thomas D Baird, Ken Chih-Chien Cheng, Yu-Chi Chen, Eugen Buehler, Scott E Martin, James Inglese, J Robert Hogg

    Published 2018-03-01
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  7. 7
    Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion

    Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion by Viviana E. Gallardo, Gaurav K. Varshney, Minnkyong Lee, Sujata Bupp, Lisha Xu, Paul Shinn, Nigel P. Crawford, James Inglese, Shawn M. Burgess

    Published 2015-06-01
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  8. 8
    A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology.

    A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology. by Teresa L Burgess, Joshua D Amason, Jeffrey S Rubin, Damien Y Duveau, Laurence Lamy, David D Roberts, Catherine L Farrell, James Inglese, Craig J Thomas, Thomas W Miller

    Published 2020-01-01
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  9. 9
    Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases

    Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases by Hao Yu, Patricia Dranchak, Zhiru Li, Ryan MacArthur, Matthew S. Munson, Nurjahan Mehzabeen, Nathan J. Baird, Kevin P. Battalie, David Ross, Scott Lovell, Clotilde K. S. Carlow, Hiroaki Suga, James Inglese

    Published 2017-04-01
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  10. 10
    Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.

    Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. by Thomas W Miller, Joshua D Amason, Elsa D Garcin, Laurence Lamy, Patricia K Dranchak, Ryan Macarthur, John Braisted, Jeffrey S Rubin, Teresa L Burgess, Catherine L Farrell, David D Roberts, James Inglese

    Published 2019-01-01
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  11. 11
    Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

    Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space by Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullie, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco, Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey R.J. Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall, Menghang Xia, Rajarshi Guha, Jason M. Rohde

    Published 2018-12-01
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