James J. Collins
James Joseph Collins (born June 26, 1965) is an American biomedical engineer and bioengineer who serves as the Termeer Professor of Medical Engineering & Science at the Massachusetts Institute of Technology (MIT), where he is also a director at the MIT Abdul Latif Jameel Clinic for Machine Learning in Health.Collins conducted research showing that artificial intelligence (AI) approaches can be used to discover novel antibiotics, such as halicin and abaucin. He serves as the Director of the Antibiotics-AI Project at MIT, which is supported by The Audacious Project, and is a member of the Harvard–MIT Program in Health Sciences and Technology. He is also a core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University and a member of the Broad Institute.
Collins is one of the founders of the field of synthetic biology, and his work on synthetic gene circuits and programmable cells has led to the development of new classes of diagnostics and therapeutics, which have influenced research in detecting and treating infections caused by emerging pathogens such as Ebola, Zika, SARS-CoV-2, and antibiotic-resistant bacteria. He is also a researcher in systems biology, having made discoveries regarding the actions of antibiotics and the emergence of antibiotic resistance.
Collins is a member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Sciences for his contributions to synthetic biology and engineered gene networks. In 2023, he was awarded a Clarivate Citation for research most likely to receive a Nobel Prize. Provided by Wikipedia
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It's no fluke: the planarian as a model for understanding schistosomes. by James J Collins, Phillip A Newmark
Published 2013-01-01
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A self‐propagating, barcoded transposon system for the dynamic rewiring of genomic networks by Max A English, Miguel A Alcantar, James J Collins
Published 2023-06-01
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Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni by Bo Wang, James J Collins III, Phillip A Newmark
Published 2013-07-01
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Engineering microbial division of labor for plastic upcycling by Teng Bao, Yuanchao Qian, Yongping Xin, James J. Collins, Ting Lu
Published 2023-09-01
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Stem cell progeny contribute to the schistosome host-parasite interface by James J Collins III, George R Wendt, Harini Iyer, Phillip A Newmark
Published 2016-03-01
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Analysis of <i>Schistosoma mansoni</i> Extracellular Vesicles Surface Glycans Reveals Potential Immune Evasion Mechanism and New Insights on Their Origins of Biogenesis by Maude Dagenais, Jared Q. Gerlach, George R. Wendt, James J. Collins, Louise E. Atkinson, Angela Mousley, Timothy G. Geary, Thavy Long
Published 2021-10-01
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Flatworm-specific transcriptional regulators promote the specification of tegumental progenitors in Schistosoma mansoni by George R Wendt, Julie NR Collins, Jimin Pei, Mark S Pearson, Hayley M Bennett, Alex Loukas, Matthew Berriman, Nick V Grishin, James J Collins III
Published 2018-03-01
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Correction: MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni. by Anna V Protasio, Stijn van Dongen, Julie Collins, Leonor Quintais, Diogo M Ribeiro, Florian Sessler, Martin Hunt, Gabriel Rinaldi, James J Collins, Anton J Enright, Matthew Berriman
Published 2022-06-01
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Single-cell RNA-seq analyses show that long non-coding RNAs are conspicuously expressed in Schistosoma mansoni gamete and tegument progenitor cell populations by David A. Morales-Vicente, David A. Morales-Vicente, Lu Zhao, Gilbert O. Silveira, Gilbert O. Silveira, Ana C. Tahira, Murilo S. Amaral, James J. Collins, Sergio Verjovski-Almeida, Sergio Verjovski-Almeida
Published 2022-09-01
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Schistosome Sulfotransferases: Mode of Action, Expression and Localization by Meghan A. Guzman, Anastasia Rugel, Sevan N. Alwan, Reid Tarpley, Alexander B. Taylor, Frédéric D. Chevalier, George R. Wendt, James J. Collins, Timothy J. C. Anderson, Stanton F. McHardy, Philip T. LoVerde
Published 2022-07-01
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Integration of metabolic modelling with machine learning to identify mechanisms underlying antibiotic killing by Wright, Sarah Natalie
Published 2017Other Authors: “…James J. Collins.…”
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Accessible and easy-to-use educational tools to teach molecular and synthetic biology using freeze-dried, cell-free technology by Huang, Ally.
Published 2019Other Authors: “…James J. Collins.…”
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Cell-free freeze-dried synthetic biology for wearable biotechnology applications by Soenksen Martinez, Luis Rubén.
Published 2020Other Authors: “…James J. Collins.…”
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Exploring and enhancing context-dependent beta-lactam antibiotic efficacy by Bening, Sarah Christine.
Published 2021Other Authors: “…James J. Collins.…”
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