PB1788: A SCREENING OF DONATED CHEMICAL PROBES TO IDENTIFY NOVEL THERAPEUTIC OPTIONS FOR ACUTE MYELOID LEUKEMIA (AML) IN CHILDHOOD by Stephanie Laszig, Raj Bhayadia, Jan-Henning Klusmann, Stefan Knapp

Get full text

Long noncoding RNAs as regulators of pediatric acute myeloid leukemia by Sina Neyazi, Michelle Ng, Dirk Heckl, Jan-Henning Klusmann

Get full text

Lost in translation: pluripotent stem cell‐derived hematopoiesis by Mania Ackermann, Steffi Liebhaber, Jan‐Henning Klusmann, Nico Lachmann

Get full text

Molecular Mechanisms of the Genetic Predisposition to Acute Megakaryoblastic Leukemia in Infants With Down Syndrome by Juliane Grimm, Juliane Grimm, Dirk Heckl, Jan-Henning Klusmann

Get full text

PB1813: REGULATORY MECHANISMS AND THERAPEUTIC POTENTIAL OF THE DLK1-DIO3 LOCUS IN PEDIATRIC ACUTE MEGAKARYOBLASTIC LEUKEMIA by Lonneke Verboon, Hasan Issa, Dirk Heckl, Jan-Henning Klusmann

Get full text

Segregated by Wealth, Health, and Development: An Analysis of Pre-School Child Health in a Medium-Sized German City by Karoline Wagner, Andreas Wienke, Christine Gröger, Jan-Henning Klusmann, Amand Führer

Get full text

P419: HARNESSING MIRNA-193B-3P MIMIC AS A POTENT THERAPEUTIC OPTION IN ACUTE MYELOID LEUKEMIA by Hasan Issa, Raj Bhayadia, Robert Winkler, Dirk Heckl, Jan-Henning Klusmann

Get full text

Leukoreductive response to the combination of sorafenib and chemotherapy in hyperleukocytosis of FLT3-ITD mutated pediatric AML by Franziska Schmidt, Miriam Erlacher, Charlotte Niemeyer, Dirk Reinhardt, Jan-Henning Klusmann

Get full text

Flow Cytometric Analysis of Autophagic Activity with Cyto-ID Staining in Primary Cells by Metodi Stankov, Diana Panayotova-Dimitrova, Martin Leverkus, Jan-Henning Klusmann, Georg Behrens

Get full text

Impact of inhibitory KIR ligand mismatch and other variables on outcomes following myeloablative posttransplant cyclophosphamide-based T-cell-replete haploidentical bone marrow tra... by Sarah Kayser, Sarah Kayser, Sarah Kayser, Emilia Salzmann-Manrique, Hubert Serve, Hubert Serve, Hubert Serve, Peter Bader, Peter Bader, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Christian Seidl, Joachim Schwäble, Gesine Bug, Gesine Bug, Gesine Bug, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich

Get full text

DNMT3A mutations are rare in childhood acute myeloid leukemia by Felicitas Thol, Michael Heuser, Frederik Damm, Jan-Henning Klusmann, Katarina Reinhardt, Dirk Reinhardt

Get full text

P467: LONG NON-CODING RNA SNHG29 IS A NOVEL MYELOID LEUKEMIA DEPENDENCY by Robert Winkler, Dirk Heckl, Michelle Ng, Reinier Boon, Hasan Issa, Raj Bhayadia, Jan-Henning Klusmann

Get full text

PB1825: IDENTIFYING GENE TARGETS FOR DRUG REPURPOSING TO COUNTER MYELOID LEUKEMIA IN CHILDREN WITH DOWN-SYNDROME (ML-DS) by Anna-Lena Schmell, Kristof Meier, Oriol Alejo-Valle, Dirk Heckel, Raj Bhayadia, Jan-Henning Klusmann

Get full text

GATA1s exerts developmental stage-specific effects in human hematopoiesis by Sofia Gialesaki, Anna Katharina Mahnken, Lena Schmid, Maurice Labuhn, Raj Bhayadia, Dirk Heckl, Jan-Henning Klusmann

Get full text

The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study by Jan-Henning Klusmann, Dirk Reinhardt, Martin Zimmermann, Bernhard Kremens, Josef Vormoor, Michael Dworzak, Ursula Creutzig, Thomas Klingebiel

Get full text

Frequency and clinical impact of viraemia in paediatric patients undergoing therapy for cancer by Anke Barnbrock, Annemarie Berger, Melchior Lauten, Martin Demmert, Jan-Henning Klusmann, Sandra Ciesek, Konrad Bochennek, Thomas Lehrnbecher

Get full text

CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo by Jana Reimer, Sabine Knöß, Maurice Labuhn, Emmanuelle M. Charpentier, Gudrun Göhring, Brigitte Schlegelberger, Jan-Henning Klusmann, Dirk Heckl

Get full text

Autolysosomal activation combined with lysosomal destabilization efficiently targets myeloid leukemia cells for cell death by Harshit Shah, Metodi Stankov, Diana Panayotova-Dimitrova, Amir Yazdi, Ramachandramouli Budida, Jan-Henning Klusmann, Georg M. N. Behrens

Get full text

Low frequency of type-I and type-II aberrations in myeloid leukemia of Down syndrome, underscoring the unique entity of this disease by Marjolein Blink, Marry M. van den Heuvel-Eibrink, Valerie de Haas, Jan-Henning Klusmann, Henrik Hasle, C. Michel Zwaan

Get full text

ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma by Catrin Heim, Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Herman Kreyenberg, Halvard B. Bonig, Halvard B. Bonig, Torsten Tonn, Torsten Tonn, Winfried S. Wels, Winfried S. Wels, Winfried S. Wels, Elise Gradhand, Elise Gradhand, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Michael T. Meister, Michael T. Meister, Marian Groot Koerkamp, Marian Groot Koerkamp, Frank C. P. Holstege, Frank C. P. Holstege, Jarno Drost, Jarno Drost, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Peter Bader, Peter Bader, Michael Merker, Michael Merker, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger

Get full text