Jan Vijg

Jan Vijg is the Lola and Saul Kramer Chairperson in Molecular Genetics at the Department of Genetics at the Albert Einstein College of Medicine, New York City, United States. Prior to this appointment, he was a professor at the Buck Institute for Research on Aging (Novato, California).

His research interests include studying genomic instability in aging. In 1989, he created the first transgenic mouse models for the study of ''in vivo'' mutagenesis. He discusses his genomic/epigenomic drift hypothesis as a cause of aging in his book ''Aging of the Genome: The Dual Role of DNA in Life and Death'''.

In his second book, ''The American Technological Challenge: Stagnation and Decline in the 21st Century'', he argues that technological innovation has decelerated ever since 1970.

Vijg is co-editor-in-chief of the journal ''Aging'' published by Impact Journals (Albany, New York). Provided by Wikipedia
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  1. 1
    Editorial: Somatic mutations, genome mosaicism and aging

    Editorial: Somatic mutations, genome mosaicism and aging by Michael A. Lodato, Jan Vijg, Jan Vijg

    Published 2023-01-01
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  2. 2
    Age-related somatic mutation burden in human tissues

    Age-related somatic mutation burden in human tissues by Peijun Ren, Xiao Dong, Jan Vijg, Jan Vijg

    Published 2022-09-01
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  3. 3
    Genome instability and aging: Cause or effect?

    Genome instability and aging: Cause or effect? by Jan Vijg, Cristina Montagna

    Published 2017-10-01
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  4. 4
    SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing

    SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing by Xiao Dong, Lei Zhang, Xiaoxiao Hao, Tao Wang, Jan Vijg, Jan Vijg

    Published 2020-11-01
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  5. 5
    Development of a Method to Implement Whole-Genome Bisulfite Sequencing of cfDNA from Cancer Patients and a Mouse Tumor Model

    Development of a Method to Implement Whole-Genome Bisulfite Sequencing of cfDNA from Cancer Patients and a Mouse Tumor Model by Elaine C. Maggi, Silvia Gravina, Haiying Cheng, Bilal Piperdi, Ziqiang Yuan, Xiao Dong, Steven K. Libutti, Jan Vijg, Jan Vijg, Jan Vijg, Cristina Montagna, Cristina Montagna

    Published 2018-01-01
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  6. 6
    A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI

    A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI by Alexander Y. Maslov, Maya Metrikin, Jan Vijg

    Published 2009-10-01
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  7. 7
    Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

    Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging by Huiwen Zheng, Jan Vijg, Atefeh Taherian Fard, Jessica Cara Mar

    Published 2023-10-01
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  8. 8
    Concurrent analysis of genome and transcriptome in one single cell

    Concurrent analysis of genome and transcriptome in one single cell by Johanna Heid, Ronald Cutler, Moonsook Lee, Jan Vijg, Alexander Y. Maslov

    Published 2024-09-01
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  9. 9
    Differences between germline and somatic mutation rates in humans and mice

    Differences between germline and somatic mutation rates in humans and mice by Brandon Milholland, Xiao Dong, Lei Zhang, Xiaoxiao Hao, Yousin Suh, Jan Vijg

    Published 2017-05-01
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  10. 10
    Improved transposon-based library preparation for the Ion Torrent platform

    Improved transposon-based library preparation for the Ion Torrent platform by Tatyana Gorbacheva, Wilber Quispe-Tintaya, Vasily N. Popov, Jan Vijg, Alexander Y. Maslov

    Published 2015-04-01
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  11. 11
    Myc-dependent genome instability and lifespan in Drosophila.

    Myc-dependent genome instability and lifespan in Drosophila. by Christina Greer, Moonsook Lee, Maaike Westerhof, Brandon Milholland, Rebecca Spokony, Jan Vijg, Julie Secombe

    Published 2013-01-01
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  12. 12
    Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing

    Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing by Wilber Quispe-Tintaya, Ryan R. White, Vasily N. Popov, Jan Vijg, Alexander Y. Maslov

    Published 2013-09-01
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  13. 13
    Age- and temperature-dependent somatic mutation accumulation in Drosophila melanogaster.

    Age- and temperature-dependent somatic mutation accumulation in Drosophila melanogaster. by Ana Maria Garcia, R Brent Calder, Martijn E T Dollé, Martha Lundell, Pankaj Kapahi, Jan Vijg

    Published 2010-05-01
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  14. 14
    High preservation of CpG cytosine methylation patterns at imprinted gene loci in liver and brain of aged mice.

    High preservation of CpG cytosine methylation patterns at imprinted gene loci in liver and brain of aged mice. by Silvia Gravina, Martijn E T Dollé, Tao Wang, Harry van Steeg, Paul Hasty, Jan Hoeijmakers, Jan Vijg

    Published 2013-01-01
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  15. 15
    Intra-organ variation in age-related mutation accumulation in the mouse.

    Intra-organ variation in age-related mutation accumulation in the mouse. by Rita A Busuttil, Ana Maria Garcia, Robert L Reddick, Martijn E T Dollé, Robert B Calder, James F Nelson, Jan Vijg

    Published 2007-09-01
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  16. 16
    Genome-wide, Single-Cell DNA Methylomics Reveals Increased Non-CpG Methylation during Human Oocyte Maturation

    Genome-wide, Single-Cell DNA Methylomics Reveals Increased Non-CpG Methylation during Human Oocyte Maturation by Bo Yu, Xiao Dong, Silvia Gravina, Önder Kartal, Timothy Schimmel, Jacques Cohen, Drew Tortoriello, Raifa Zody, R. David Hawkins, Jan Vijg

    Published 2017-07-01
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  17. 17
    Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers

    Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers by Shixiang Sun, Kristina Brazhnik, Moonsook Lee, Alexander Y. Maslov, Yi Zhang, Zhenqiu Huang, Susan Klugman, Ben H. Park, Jan Vijg, Cristina Montagna

    Published 2022-03-01
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  18. 18
    A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations

    A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations by Seung-Soo Kim, Adam D. Hudgins, Adam D. Hudgins, Brenda Gonzalez, Sofiya Milman, Nir Barzilai, Jan Vijg, Zhidong Tu, Yousin Suh, Yousin Suh

    Published 2021-06-01
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  19. 19
    Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung

    Global, integrated analysis of methylomes and transcriptomes from laser capture microdissected bronchial and alveolar cells in human lung by Xiao Dong, Miao Shi, Moonsook Lee, Rafael Toro, Silvia Gravina, Weiguo Han, Shoya Yasuda, Tao Wang, Zhengdong Zhang, Jan Vijg, Yousin Suh, Simon D. Spivack

    Published 2018-03-01
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  20. 20
    Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants.

    Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants. by Maria Delio, Kunjan Patel, Alex Maslov, Robert W Marion, Thomas V McDonald, Evan M Cadoff, Aaron Golden, John M Greally, Jan Vijg, Bernice Morrow, Cristina Montagna

    Published 2015-01-01
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