Janet Thornton

Janet Thornton <!-- when?? --> Dame Janet Maureen Thornton, (born 23 May 1949) is a senior scientist and director emeritus at the European Bioinformatics Institute (EBI), part of the European Molecular Biology Laboratory (EMBL). She is one of the world's leading researchers in structural bioinformatics, using computational methods to understand protein structure and function. She served as director of the EBI from October 2001 to June 2015, and played a key role in ELIXIR. Provided by Wikipedia
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  1. 1
    PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure.

    PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. by Marialuisa Pellegrini-Calace, Tim Maiwald, Janet M Thornton

    Published 2009-07-01
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  2. 2
    Author Correction: Temporal changes in the gene expression heterogeneity during brain development and aging

    Author Correction: Temporal changes in the gene expression heterogeneity during brain development and aging by Ulaş Işıldak, Mehmet Somel, Janet M. Thornton, Handan Melike Dönertaş

    Published 2023-06-01
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  3. 3
    A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases

    A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases by Lorena Magraner-Pardo, Roman A. Laskowski, Tirso Pons, Janet M. Thornton

    Published 2021-07-01
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  4. 4
    An automated protocol for modelling peptide substrates to proteases

    An automated protocol for modelling peptide substrates to proteases by Rodrigo Ochoa, Mikhail Magnitov, Roman A. Laskowski, Pilar Cossio, Janet M. Thornton

    Published 2020-12-01
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  5. 5
    Functional conservation in genes and pathways linking ageing and immunity

    Functional conservation in genes and pathways linking ageing and immunity by Daniel K. Fabian, Matías Fuentealba, Handan Melike Dönertaş, Linda Partridge, Janet M. Thornton

    Published 2021-05-01
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  6. 6
    Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing.

    Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. by Irene Papatheodorou, Matthias Ziehm, Daniela Wieser, Nazif Alic, Linda Partridge, Janet M Thornton

    Published 2012-01-01
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  7. 7
    Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset.

    Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset. by Tjaart A P de Beer, Roman A Laskowski, Sarah L Parks, Botond Sipos, Nick Goldman, Janet M Thornton

    Published 2013-01-01
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  8. 8
    Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.

    Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies. by Nicholas Furnham, Ian Sillitoe, Gemma L Holliday, Alison L Cuff, Roman A Laskowski, Christine A Orengo, Janet M Thornton

    Published 2012-01-01
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  9. 9
    Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

    Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. by Cathy Slack, Christian Werz, Daniela Wieser, Nazif Alic, Andrea Foley, Hugo Stocker, Dominic J Withers, Janet M Thornton, Ernst Hafen, Linda Partridge

    Published 2010-03-01
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  10. 10
    Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity.

    Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity. by Nidhi Tyagi, Edward J Farnell, Colin M Fitzsimmons, Stephanie Ryan, Edridah Tukahebwa, Rick M Maizels, David W Dunne, Janet M Thornton, Nicholas Furnham

    Published 2015-10-01
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  11. 11
    Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity

    Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity by Ekin Bolukbasi, Mobina Khericha, Jennifer C. Regan, Dobril K. Ivanov, Jennifer Adcott, Miranda C. Dyson, Tobias Nespital, Janet M. Thornton, Nazif Alic, Linda Partridge

    Published 2017-10-01
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  12. 12
    Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1

    Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1 by Daniel E. Martin-Herranz, Erfan Aref-Eshghi, Marc Jan Bonder, Thomas M. Stubbs, Sanaa Choufani, Rosanna Weksberg, Oliver Stegle, Bekim Sadikovic, Wolf Reik, Janet M. Thornton

    Published 2019-08-01
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  13. 13
    DamID in C. elegans reveals longevity‐associated targets of DAF‐16/FoxO

    DamID in C. elegans reveals longevity‐associated targets of DAF‐16/FoxO by Eugene Schuster, Joshua J McElwee, Jennifer M A Tullet, Ryan Doonan, Filip Matthijssens, John S Reece‐Hoyes, Ian A Hope, Jacques R Vanfleteren, Janet M Thornton, David Gems

    Published 2010-01-01
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  14. 14
    DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.

    DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans. by Jennifer M A Tullet, Caroline Araiz, Matthew J Sanders, Catherine Au, Alexandre Benedetto, Irene Papatheodorou, Emily Clark, Kathrin Schmeisser, Daniel Jones, Eugene F Schuster, Janet M Thornton, David Gems

    Published 2014-02-01
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  15. 15
    Data-driven identification of ageing-related diseases from electronic health records

    Data-driven identification of ageing-related diseases from electronic health records by Valerie Kuan, Helen C. Fraser, Melanie Hingorani, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Kenan Direk, Dorothea Nitsch, Rohini Mathur, Constantinos A. Parisinos, R. Thomas Lumbers, Reecha Sofat, Ian C. K. Wong, Juan P. Casas, Janet M. Thornton, Harry Hemingway, Linda Partridge, Aroon D. Hingorani

    Published 2021-02-01
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  16. 16
    A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]

    A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations] by Christine Orengo, Sameer Velankar, Shoshana Wodak, Vincent Zoete, Alexandre M.J.J. Bonvin, Arne Elofsson, K. Anton Feenstra, Dietland L. Gerloff, Thomas Hamelryck, John M. Hancock, Manuela Helmer-Citterich, Adam Hospital, Modesto Orozco, Anastassis Perrakis, Matthias Rarey, Claudio Soares, Joel L. Sussman, Janet M. Thornton, Pierre Tuffery, Gabor Tusnady, Rikkert Wierenga, Tiina Salminen, Bohdan Schneider

    Published 2020-04-01
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