Janet Thornton

Janet Thornton <!-- when?? --> Dame Janet Maureen Thornton, (born 23 May 1949) is a senior scientist and director emeritus at the European Bioinformatics Institute (EBI), part of the European Molecular Biology Laboratory (EMBL). She is one of the world's leading researchers in structural bioinformatics, using computational methods to understand protein structure and function. She served as director of the EBI from October 2001 to June 2015, and played a key role in ELIXIR. Provided by Wikipedia
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  1. 1
    Evolutionary models for formation of network motifs and modularity in the Saccharomyces transcription factor network.

    Evolutionary models for formation of network motifs and modularity in the Saccharomyces transcription factor network. by Jonathan J Ward, Janet M Thornton

    Published 2007-10-01
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  2. 2
    PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure.

    PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. by Marialuisa Pellegrini-Calace, Tim Maiwald, Janet M Thornton

    Published 2009-07-01
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  3. 3
    Prediction of Protein Function from Structure: Insights from Methods for the Detection of Local Structural Similarities

    Prediction of Protein Function from Structure: Insights from Methods for the Detection of Local Structural Similarities by Rafael J. Najmanovich, James W. Torrance, Janet M. Thornton

    Published 2005-06-01
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  4. 4
    Author Correction: Temporal changes in the gene expression heterogeneity during brain development and aging

    Author Correction: Temporal changes in the gene expression heterogeneity during brain development and aging by Ulaş Işıldak, Mehmet Somel, Janet M. Thornton, Handan Melike Dönertaş

    Published 2023-06-01
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  5. 5
    A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases

    A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases by Lorena Magraner-Pardo, Roman A. Laskowski, Tirso Pons, Janet M. Thornton

    Published 2021-07-01
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  6. 6
    An automated protocol for modelling peptide substrates to proteases

    An automated protocol for modelling peptide substrates to proteases by Rodrigo Ochoa, Mikhail Magnitov, Roman A. Laskowski, Pilar Cossio, Janet M. Thornton

    Published 2020-12-01
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  7. 7
    Characterising Complex Enzyme Reaction Data.

    Characterising Complex Enzyme Reaction Data. by Handan Melike Dönertaş, Sergio Martínez Cuesta, Syed Asad Rahman, Janet M Thornton

    Published 2016-01-01
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  8. 8
    Functional conservation in genes and pathways linking ageing and immunity

    Functional conservation in genes and pathways linking ageing and immunity by Daniel K. Fabian, Matías Fuentealba, Handan Melike Dönertaş, Linda Partridge, Janet M. Thornton

    Published 2021-05-01
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  9. 9
    Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing.

    Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. by Irene Papatheodorou, Matthias Ziehm, Daniela Wieser, Nazif Alic, Linda Partridge, Janet M Thornton

    Published 2012-01-01
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  10. 10
    Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders

    Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders by Rodrigo Ochoa, Rodrigo Ochoa, Roman A. Laskowski, Janet M. Thornton, Pilar Cossio, Pilar Cossio

    Published 2021-03-01
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  11. 11
    Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure.

    Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure. by John A Capra, Roman A Laskowski, Janet M Thornton, Mona Singh, Thomas A Funkhouser

    Published 2009-12-01
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  12. 12
    Using the drug-protein interactome to identify anti-ageing compounds for humans.

    Using the drug-protein interactome to identify anti-ageing compounds for humans. by Matías Fuentealba, Handan Melike Dönertaş, Rhianna Williams, Johnathan Labbadia, Janet M Thornton, Linda Partridge

    Published 2019-01-01
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  13. 13
    Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset.

    Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset. by Tjaart A P de Beer, Roman A Laskowski, Sarah L Parks, Botond Sipos, Nick Goldman, Janet M Thornton

    Published 2013-01-01
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  14. 14
    A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data.

    A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data. by Dobril K Ivanov, Gerrit Bostelmann, Benoit Lan-Leung, Julie Williams, Linda Partridge, Valentina Escott-Price, Janet M Thornton

    Published 2020-01-01
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  15. 15
    Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.

    Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies. by Nicholas Furnham, Ian Sillitoe, Gemma L Holliday, Alison L Cuff, Roman A Laskowski, Christine A Orengo, Janet M Thornton

    Published 2012-01-01
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  16. 16
    Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

    Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. by Cathy Slack, Christian Werz, Daniela Wieser, Nazif Alic, Andrea Foley, Hugo Stocker, Dominic J Withers, Janet M Thornton, Ernst Hafen, Linda Partridge

    Published 2010-03-01
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  17. 17
    Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity.

    Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity. by Nidhi Tyagi, Edward J Farnell, Colin M Fitzsimmons, Stephanie Ryan, Edridah Tukahebwa, Rick M Maizels, David W Dunne, Janet M Thornton, Nicholas Furnham

    Published 2015-10-01
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  18. 18
    Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity

    Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity by Ekin Bolukbasi, Mobina Khericha, Jennifer C. Regan, Dobril K. Ivanov, Jennifer Adcott, Miranda C. Dyson, Tobias Nespital, Janet M. Thornton, Nazif Alic, Linda Partridge

    Published 2017-10-01
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  19. 19
    Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

    Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling by Nazif Alic, T Daniel Andrews, Maria E Giannakou, Irene Papatheodorou, Cathy Slack, Matthew P Hoddinott, Helena M Cochemé, Eugene F Schuster, Janet M Thornton, Linda Partridge

    Published 2011-06-01
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  20. 20
    Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1

    Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1 by Daniel E. Martin-Herranz, Erfan Aref-Eshghi, Marc Jan Bonder, Thomas M. Stubbs, Sanaa Choufani, Rosanna Weksberg, Oliver Stegle, Bekim Sadikovic, Wolf Reik, Janet M. Thornton

    Published 2019-08-01
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