Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model by Mai T. Ngo, Jann N. Sarkaria, Brendan A.C. Harley

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Editorial: Targeted Therapies for Glioblastoma: A Critical Appraisal by Shiv K. Gupta, Sani H. Kizilbash, David J. Daniels, Jann N. Sarkaria

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Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain. by Gobinda Sarkar, Geoffry L Curran, Jann N Sarkaria, Val J Lowe, Robert B Jenkins

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The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma by Rodrigo Javier, Wenxia Wang, Michael Drumm, Kathleen McCortney, Jann N. Sarkaria, Craig Horbinski

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MDM2 Inhibition in the Treatment of Glioblastoma: From Concept to Clinical Investigation by Karolina I. Pellot Ortiz, Julian S. Rechberger, Leo F. Nonnenbroich, David J. Daniels, Jann N. Sarkaria

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IL-13Rα2 Status Predicts GB-13 (IL13.E13K-PE4E) Efficacy in High-Grade Glioma by Julian S. Rechberger, Kendra A. Porath, Liang Zhang, Cody L. Nesvick, Randy S. Schrecengost, Jann N. Sarkaria, David J. Daniels

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Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth by Nahom Teferi, Akalanka Ekanayake, Stephenson B. Owusu, Thomas O. Moninger, Jann N. Sarkaria, Alexei V. Tivanski, Michael S. Petronek

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Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors by Jessica I. Griffith, Sneha Rathi, Wenqiu Zhang, Wenjuan Zhang, Lester R. Drewes, Jann N. Sarkaria, William F. Elmquist

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The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion by Anna M. Jermakowicz, Matthew J. Rybin, Robert K. Suter, Jann N. Sarkaria, Zane Zeier, Yangbo Feng, Nagi G. Ayad

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H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers by Dong Fang, Haiyun Gan, Liang Cheng, Jeong-Heon Lee, Hui Zhou, Jann N Sarkaria, David J Daniels, Zhiguo Zhang

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Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells. by Zachary D Nagel, Andrew A Beharry, Patrizia Mazzucato, Gaspar J Kitange, Jann N Sarkaria, Eric T Kool, Leona D Samson

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Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype. by Laura J Lewis-Tuffin, Fausto Rodriguez, Caterina Giannini, Bernd Scheithauer, Brian M Necela, Jann N Sarkaria, Panos Z Anastasiadis

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IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling by Claudia R. Oliva, Brian Halloran, Anita B. Hjelmeland, Ana Vazquez, Shannon M. Bailey, Jann N. Sarkaria, Corinne E. Griguer

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Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells by Ravi D. Rao, Ann C. Mladek, Jeffrey D. Lamont, Jennie M. Goble, Charles Erlichman, C. David James, Jann N. Sarkaria

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Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition. by R Marisol Herrera-Perez, Sherry L Voytik-Harbin, Jann N Sarkaria, Karen E Pollok, Melissa L Fishel, Jenna L Rickus

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Quantifying Glioblastoma Drug Response Dynamics Incorporating Treatment Sensitivity and Blood Brain Barrier Penetrance From Experimental Data by Susan Christine Massey, Javier C. Urcuyo, Bianca Maria Marin, Jann N. Sarkaria, Kristin R. Swanson, Kristin R. Swanson, Kristin R. Swanson

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A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma by Wan-Hsin Lin, Ryan W. Feathers, Lisa M. Cooper, Laura J. Lewis-Tuffin, Jiaxiang Chen, Jann N. Sarkaria, Panos Z. Anastasiadis

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Influence of Hyaluronic Acid Transitions in Tumor Microenvironment on Glioblastoma Malignancy and Invasive Behavior by Jee-Wei E. Chen, Sara Pedron, Peter Shyu, Yuhang Hu, Jann N. Sarkaria, Brendan A. C. Harley, Brendan A. C. Harley

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Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells by Bryan G. Harder, Sen Peng, Christopher P. Sereduk, Andrej M. Sodoma, Gaspar J. Kitange, Joseph C. Loftus, Jann N. Sarkaria, Nhan L. Tran

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Inhibition of Multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme by Amanda eTivnan, Zaitun eZakaria, Caitrin eO'Leary, Donat eKogel, Jenny L Pokorny, Jann N Sarkaria, Jochen H M Prehn

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