Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types by Riyue Bao, Daniel Stapor, Jason J. Luke

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Targeting Cbl-b in cancer immunotherapy by Riyue Bao, Jason J. Luke, Ryan C. Augustin

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Therapeutic Advancements Across Clinical Stages in Melanoma, With a Focus on Targeted Immunotherapy by Claudia Trojaniello, Jason J. Luke, Paolo A. Ascierto

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Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a ran... by Thomas Gajewski, Yuanyuan Zha, Jason J. Luke, Karen Matijevich

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High Throughput Multi-Omics Approaches for Clinical Trial Evaluation and Drug Discovery by Jessica M. Zielinski, Jason J. Luke, Silvia Guglietta, Carsten Krieg

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Case Report: Single Dose Anti-PD1 in a Patient With Metastatic Melanoma and Cardiac Allograft by Amy E. Goodman, Lilit Karapetyan, Lilit Karapetyan, Melissa Pugliano-Mauro, Melissa Pugliano-Mauro, Joshua E. Levenson, Joshua E. Levenson, Jason J. Luke, Jason J. Luke

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The Evolution of Radiation Therapy in Metastatic Breast Cancer: From Local Therapy to Systemic Agent by Jessica M. S. Jutzy, Jeffrey M. Lemons, Jason J. Luke, Steven J. Chmura

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Editorial: Mechanisms of Lymphocyte Exclusion in the Tumor Microenvironment by Rieneke van de Ven, Rieneke van de Ven, Rieneke van de Ven, Carlo B. Bifulco, Carlo B. Bifulco, Carlo B. Bifulco, Jason J. Luke, Jason J. Luke, Sarah E. Church

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Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy by Riyue Bao, Aung Naing, Lawrence Fong, Jason J. Luke, Robert D. Leone, Ryan C. Augustin

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A case of dual-mechanism immune-related anaemia in a patient with metastatic melanoma treated with nivolumab and ipilimumab by Thomas F Gajewski, Jason J Luke, Daniel J Olson, Padma Rajagopal, Melissa Y Tjota, Girish Venkataraman

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Pseudoprogression manifesting as recurrent ascites with anti-PD-1 immunotherapy in urothelial bladder cancer by Randy F. Sweis, Yuanyuan Zha, Lomax Pass, Brian Heiss, Tara Chongsuwat, Jason J. Luke, Thomas F. Gajewski, Russell Szmulewitz

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Immune-Related Adverse Events in PD-1 Treated Melanoma and Impact Upon Anti-Tumor Efficacy: A Real World Analysis by Melissa L. Bastacky, Hong Wang, Dylan Fortman, Zahra Rahman, Gerard P. Mascara, Timothy Brenner, Yana G. Najjar, Yana G. Najjar, Jason J. Luke, Jason J. Luke, John M. Kirkwood, John M. Kirkwood, Hassane M. Zarour, Hassane M. Zarour, Diwakar Davar, Diwakar Davar

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Immunogenomic determinants of tumor microenvironment correlate with superior survival in high-risk neuroblastoma by Ami V Desai, Stefani Spranger, Thomas F Gajewski, Yuanyuan Zha, Jason J Luke, Peter Pytel, Kyle Hernandez, Samuel L Volchenboum, Susan L Cohn

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Cardiotoxicity associated with CTLA4 and PD1 blocking immunotherapy by Matthias Pauschinger, F. Stephen Hodi, Patrick A. Ott, Thomas F. Gajewski, Hussein Tawbi, Jason J. Luke, Lucie Heinzerling, Aliya N. Husain, Azadeh Tajmir-Riahi, Evan J. Lipson

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BMI, irAE, and gene expression signatures associate with resistance to immune-checkpoint inhibition and outcomes in renal cell carcinoma by Brian W. Labadie, Ping Liu, Riyue Bao, Michael Crist, Ricardo Fernandes, Laura Ferreira, Scott Graupner, Andrew S. Poklepovic, Ignacio Duran, Saman Maleki Vareki, Arjun V. Balar, Jason J. Luke

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Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study by Michael Smith, Ignacio Garrido-Laguna, Aung Naing, Lance Leopold, Jason J Luke, Kai Ding, Solmaz Sahebjam, Ryan Geschwindt, John D Powderly, John J Nemunaitis, Aaron S Mansfield, Wells A Messersmith, Patricia M LoRusso, Jordan D Berlin

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Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases by Mark C. Korpics, Benjamin E. Onderdonk, Rebekah E. Dadey, Jared H. Hara, Lilit Karapetyan, Yuanyuan Zha, Theodore G. Karrison, Adam C. Olson, Gini F. Fleming, Ralph R. Weichselbaum, Riyue Bao, Steven J. Chmura, Jason J. Luke

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Tumor-reprogrammed resident T cells resist radiation to control tumors by Ainhoa Arina, Michael Beckett, Christian Fernandez, Wenxin Zheng, Sean Pitroda, Steven J. Chmura, Jason J. Luke, Martin Forde, Yuzhu Hou, Byron Burnette, Helena Mauceri, Israel Lowy, Tasha Sims, Nikolai Khodarev, Yang-Xin Fu, Ralph R. Weichselbaum

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Phase I dose-escalation and pharmacodynamic study of STING agonist E7766 in advanced solid tumors by Yan Zhang, Andrés Cervantes, Stephane Champiat, Aurélien Marabelle, Patricia LoRusso, Jason J Luke, Robert Haddad, David J Pinato, Dejan Juric, María de Miguel, Won Seog Kim, Xiaobin Yuan, Peter J Hosein, Anupam M Desai, Yuanxin Rong

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888 Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma by Riyue Bao, Hassane Zarour, Yana G Najjar, Diwakar Davar, Cindy Sander, Jason J Luke, John M Kirkwood, Ryan C Augustin, Aofei Li, Marion Joy, Maureen Lyons, Katelyn Smith, Brian Isett, Sarah Brodeur, Mary Pham, Peter C Lucas