ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19 by Lei Huang, Riyue Bao, Kyle Hernandez, Jason John Luke

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Jeffrey S Weber, MD, PhD (1952–2024): in memoriam to discovery, friendship and family by Pedro J Romero, Bernard A Fox, Iman Osman, Omid Hamid, Paolo A Ascierto, Michael T Lotze, Jason John Luke, James J Mulé

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Anti-CD73 antibody activates human B cells, enhances humoral responses and induces redistribution of B cells in patients with cancer by Thomas Marron, Brett G M Hughes, Jason John Luke, Shenshen Hu, Suresh Mahabhashyam, Richard A Miller, William B Jones, Jaime R Merchan, Stephen B Willingham

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First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid... by Ravit Geva, Jennifer Mataraza, Osama Rahma, Jason John Luke, Philippe L Bedard, Sarina A Piha-Paul, Angad Singh, Tira J Tan, Darren WT Lim, Cinta Hierro, Toshikiko Doi, Alexander Lesokhin, Javier Otero, Lisa Nardi, Alexandros Xyrafas, Xinhui Chen

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Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma by Riyue Bao, Yana G Najjar, Diwakar Davar, Cindy Sander, John M Kirkwood, Jason John Luke, Sarah Newman, Hassane M Zarour, Peter Lucas, Ryan C Augustin, Aofei Li, Marion Joy, Maureen Lyons, Mary P Pham, Katelyn Smith, Brian Isett

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Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma: Outcomes in histopathologic subgroups from the randomized, double-blind, phase 3 KEYNOTE-716... by Dirk Schadendorf, Caroline Robert, Reinhard Dummer, Luis de la Cruz-Merino, Paolo A Ascierto, John M Kirkwood, Georgina V Long, Jacek Mackiewicz, Richard A Scolyer, Piotr Rutkowski, Jean-Jacques Grob, Jason John Luke, Michele Del Vecchio, Mizuho Kalabis, Adnan Khattak, Matteo S Carlino, Yujie Zhao, Alexander Eggermont, Vanna Chiarion Sileni, Clemens Krepler

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Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy by Dirk Schadendorf, Celeste Lebbe, Teresa Amaral, Benjamin Weide, Mariaelena Capone, Gabriele Madonna, Lucia Festino, Reinhard Dummer, Domenico Mallardo, Paolo A Ascierto, Piotr Rutkowski, Jason John Luke, Kilian Wistuba-Hamprecht, Mitchell P Levesque, Roberta Turiello, Elva Morretta, Maria Chiara Monti, Rosa Azzaro, Laurence Imhof, Marc Chevrier, Antje Sucker, Aldo Pinto, Silvana Morello

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Radiomic analysis of patient and interorgan heterogeneity in response to immunotherapies and BRAF-targeted therapy in metastatic melanoma by Riyue Bao, Yana G Najjar, Diwakar Davar, John M Kirkwood, Jason John Luke, Sarah Newman, Hassane M Zarour, Afsaneh Amouzegar, Rivka R Colen, Murat Ak, Priyadarshini Mamindla, Serafettin Zenkin, Vishal Peddagangireddy, Sarah Behr, Alexandra G Tompkins, Zane N Gray, Rebekah E Dadey, Nasim Batavani, Nursima Ak, Taha Yasin Pak, Mohammadreza Amjadzadeh, Amy Goodman, Darcy L Ploucha, Curtis Tatsuoka

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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

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