Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections by Sina Bavari, Rekha G. Panchal, Dan V. Mourich, Lisa S. Welch, Nicole L. Garza, Jay B. Wells, Travis K. Warren, Patrick L. Iversen

Get full text

Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges) by John M. Dye, Kelly L. Warfield, Jay B. Wells, Robert C. Unfer, Sergey Shulenin, Hong Vu, Donald K. Nichols, M. Javad Aman, Sina Bavari

Get full text

Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation. by Karen A O Martins, Jesse T Steffens, Sean A van Tongeren, Jay B Wells, Alison A Bergeron, Samuel P Dickson, John M Dye, Andres M Salazar, Sina Bavari

Get full text

Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles. by Kelly L Warfield, John M Dye, Jay B Wells, Robert C Unfer, Frederick W Holtsberg, Sergey Shulenin, Hong Vu, Dana L Swenson, Sina Bavari, M Javad Aman

Get full text

Euthanasia Assessment in Ebola Virus Infected Nonhuman Primates by Travis K. Warren, John C. Trefry, Shannon T. Marko, Taylor B. Chance, Jay B. Wells, William D. Pratt, Joshua C. Johnson, Eric M. Mucker, Sarah L. Norris, Mark Chappell, John M. Dye, Anna N. Honko

Get full text

A systematic screen of FDA-approved drugs for inhibitors of biological threat agents. by Peter B Madrid, Sidharth Chopra, Ian D Manger, Lynne Gilfillan, Tiffany R Keepers, Amy C Shurtleff, Carol E Green, Lalitha V Iyer, Holli Hutcheson Dilks, Robert A Davey, Andrey A Kolokoltsov, Ricardo Carrion, Jean L Patterson, Sina Bavari, Rekha G Panchal, Travis K Warren, Jay B Wells, Walter H Moos, Raelyn L Burke, Mary J Tanga

Get full text

Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing by Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Laura M. Gomba, Kristan A. O’Brien, Franco D. Rossi, Xiankun Zeng, Eric D. Lee, Jo Lynne W. Raymond, Diana A. Hoffman, Alexandra N. Jay, Elizabeth S. Brown, Paul A. Kallgren, Sarah L. Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C. Chu, Bali Singh, Roy Bannister, Danielle P. Porter, Tomas Cihlar, John M. Dye

Get full text

A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques by Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean A. Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Darrell L. Wetzel, Heather L. Esham, Nicole L. Garza, Eric D. Lee, Jennifer L. Scruggs, Franco D. Rossi, Elizabeth S. Brown, Jessica M. Weidner, Laura M. Gomba, Kristan A. O’Brien, Alexandra N. Jay, Xiankun Zeng, Kristen S. Akers, Paul A. Kallgren, Ethan Englund, J. Matthew Meinig, Jeffrey R. Kugelman, Joshua L. Moore, Holly A. Bloomfield, Sarah L. Norris, Tameka Bryan, Christie H. Scheuerell, Jesse Walters, Nevena Mollova, Christiana Blair, Darius Babusis, Tomas Cihlar, Danielle P. Porter, Bali Singh, Charlotte Hedskog, Sina Bavari, Travis K. Warren, Roy Bannister

Get full text