Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. by James M Young, Ifedayo M O Adetifa, Martin O C Ota, Jayne S Sutherland

Get full text

Analysis of cellular and soluble profiles in QuantiFERON nonconverters, converters, and reverters in the Gambia by Lydia Medawar, Hatimi Mohd Tukiman, Georgetta Mbayo, Simon Donkor, Olumuyiwa Owolabi, Jayne S. Sutherland

Get full text

Changes in Mycobacterium tuberculosis-Specific Immunity With Influenza co-infection at Time of TB Diagnosis by Joseph Mendy, Sheikh Jarju, Rhiannon Heslop, Rhiannon Heslop, Adama L. Bojang, Beate Kampmann, Jayne S. Sutherland

Get full text

Changes in Host Cytokine Patterns of TB Patients with Different Bacterial Loads Detected Using 16S rRNA Analysis. by Rhiannon Heslop, Adama L Bojang, Sheikh Jarju, Joseph Mendy, Sarah Mulwa, Ousman Secka, Francis S Mendy, Olumuyiwa Owolabi, Beate Kampmann, Jayne S Sutherland

Get full text

Highly accurate diagnosis of pleural tuberculosis by immunological analysis of the pleural effusion. by Jayne S Sutherland, Danlani Garba, Augustin E Fombah, Awa Mendy-Gomez, Francis S Mendy, Martin Antonio, John Townend, Readon C Ideh, Tumani Corrah, Martin O C Ota

Get full text

IL-17 Production from T Helper 17, Mucosal-Associated Invariant T, and γδ Cells in Tuberculosis Infection and Disease by Felicity Coulter, Felicity Coulter, Amy Parrish, Amy Parrish, Declan Manning, Declan Manning, Beate Kampmann, Joseph Mendy, Mathieu Garand, David M. Lewinsohn, Eleanor M. Riley, Jayne S. Sutherland

Get full text

Association of slow recovery of Mycobacterium africanum-infected patients posttreatment with high content of Persister-Like bacilli in pretreatment sputum by Leopold D Tientcheu, Andrew Bell, Oumie Secka, Abigail Ayorinde, Jacob Otu, Nathalie J Garton, Jayne S Sutherland, Martin O Ota, Martin Antonio, H M Dockrell, Beate Kampmann, Michael R Barer

Get full text

Face mask sampling for the detection of Mycobacterium tuberculosis in expelled aerosols. by Caroline M L Williams, Eddy S G Cheah, Joanne Malkin, Hemu Patel, Jacob Otu, Kodjovi Mlaga, Jayne S Sutherland, Martin Antonio, Nelun Perera, Gerrit Woltmann, Pranabashis Haldar, Natalie J Garton, Michael R Barer

Get full text

Identification of probable early-onset biomarkers for tuberculosis disease progression. by Jayne S Sutherland, Philip C Hill, Ifedayo M Adetifa, Bouke C de Jong, Simon Donkor, Simone A Joosten, Lizet Opmeer, Marielle C Haks, Tom H M Ottenhoff, Richard A Adegbola, Martin O C Ota

Get full text

The impact of prior SARS-CoV-2 infection on host inflammatory cytokine profiles in patients with TB or other respiratory diseases by Annabelle Cottam, Ismaila L. Manneh, Awa Gindeh, Abdou K. Sillah, Ousainou Cham, Joseph Mendy, Amadou Barry, Edward G. Coker, Georgetta K. Daffeh, Simon Badjie, Salieu Barry, Olumuyiwa Owolabi, Jill Winter, Gerhard Walzl, Jayne S. Sutherland

Get full text

Minimal Sex-Differential Modulation of Reactivity to Pathogens and Toll-Like Receptor Ligands following Infant Bacillus Calmette–Guérin Russia Vaccination by Fatoumatta Darboe, Jane U. Adetifa, John Reynolds, Safayet Hossin, Magdalena Plebanski, Magdalena Plebanski, Mihai G. Netea, Sarah L. Rowland-Jones, Sarah L. Rowland-Jones, Jayne S. Sutherland, Katie L. Flanagan, Katie L. Flanagan, Katie L. Flanagan

Get full text

Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers by Molly A. Vickers, Molly A. Vickers, Fatoumatta Darboe, Caleb N. Muefong, Georgetta Mbayo, Amadou Barry, Awa Gindeh, Sainabou Njie, Abi-Janet Riley, Binta Sarr, Basil Sambou, Hazel M. Dockrell, Salome Charalambous, Andrea Rachow, Andrea Rachow, Olumuyiwa Owolabi, Shamanthi Jayasooriya, Shamanthi Jayasooriya, Jayne S. Sutherland

Get full text

Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection by Natalie E. Nieuwenhuizen, Geraldine Nouailles, Jayne S. Sutherland, Joanna Zyla, Arja H. Pasternack, Jan Heyckendorf, Björn C. Frye, Kerstin Höhne, Ulrike Zedler, Silke Bandermann, Ulrike Abu Abed, Volker Brinkmann, Birgitt Gutbier, Martin Witzenrath, Norbert Suttorp, Gernot Zissel, Christoph Lange, Olli Ritvos, Stefan H. E. Kaufmann

Get full text

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis by Stuart Meier, James A. Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, Andre G. Loxton, Stephanus T. Malherbe, Daniel E. Zak, Ethan Thompson, Fergal J. Duffy, Stefan H. E. Kaufmann, Tom H. M. Ottenhoff, Thomas J. Scriba, Sara Suliman, Jayne S. Sutherland, Jill Winter, Helena Kuivaniemi, Gerhard Walzl, Gerard Tromp

Get full text

Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease by Hygon Mutavhatsindi, Gian D. van der Spuy, Stephanus T. Malherbe, Jayne S. Sutherland, Annemieke Geluk, Harriet Mayanja-Kizza, Amelia C. Crampin, Desta Kassa, Rawleigh Howe, Adane Mihret, Jacob A. Sheehama, Emmanuel Nepolo, Gunar Günther, Hazel M. Dockrell, Paul L. A. M. Corstjens, Kim Stanley, Gerhard Walzl, Novel N. Chegou, the AE-TBC ScreenTB Consortia

Get full text

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis. by Stuart Meier, James A Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, Andre G Loxton, Stephanus T Malherbe, Daniel E Zak, Ethan Thompson, Fergal J Duffy, Stefan H E Kaufmann, Tom H M Ottenhoff, Thomas J Scriba, Sara Suliman, Jayne S Sutherland, Jill Winter, Helena Kuivaniemi, Gerhard Walzl, Gerard Tromp, GC6-74 Consortium, Catalysis TB Biomarkers Consortium

Get full text

Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis by Rosalie Lubbers, Jayne S. Sutherland, Delia Goletti, Roelof A. de Paus, Coline H. M. van Moorsel, Marcel Veltkamp, Stefan M. T. Vestjens, Willem J. W. Bos, Willem J. W. Bos, Linda Petrone, Franca Del Nonno, Ingeborg M. Bajema, Karin Dijkman, Frank A. W. Verreck, Gerhard Walzl, Kyra A. Gelderman, Geert H. Groeneveld, Annemieke Geluk, Tom H. M. Ottenhoff, Simone A. Joosten, Leendert A. Trouw

Get full text

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. by Jayne S Sutherland, Maeve K Lalor, Gillian F Black, Lyn R Ambrose, Andre G Loxton, Novel N Chegou, Desta Kassa, Adane Mihret, Rawleigh Howe, Harriet Mayanja-Kizza, Marie P Gomez, Simon Donkor, Kees Franken, Willem Hanekom, Michel R Klein, Shreemanta K Parida, W Henry Boom, Bonnie A Thiel, Amelia C Crampin, Martin Ota, Gerhard Walzl, Tom H M Ottenhoff, Hazel M Dockrell, Stefan H E Kaufmann, GCGH Biomarkers for TB consortium

Get full text

Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome by Fergal J. Duffy, January Weiner, Scott Hansen, David L. Tabb, Sara Suliman, Ethan Thompson, Jeroen Maertzdorf, Smitha Shankar, Gerard Tromp, Shreemanta Parida, Shreemanta Parida, Drew Dover, Michael K. Axthelm, Jayne S. Sutherland, Hazel M. Dockrell, Tom H. M. Ottenhoff, Thomas J. Scriba, Louis J. Picker, Gerhard Walzl, Stefan H. E. Kaufmann, Daniel E. Zak, The GC6-74 Consortium, S. H. E. Kaufmann, S. K. Parida, R. Golinski, J. Maertzdorf, J. Weiner, M. Jacobson, G. McEwen, G. Walzl, G. F. Black, G. van der Spuy, K. Stanley, M. Kriel, N. Du Plessis, N. Nene, A. G. Loxton, N. N. Chegou, S. Suliman, T. Scriba, M. Fisher, H. Mahomed, J. Hughes, K. Downing, A. Penn-Nicholson, H. Mulenga, B. Abel, M. Bowmaker, B. Kagina, W. Kwong, C. W. Hanekom, T. H. M. Ottenhoff, M. R. Klein, M. C. Haks, K. L. Franken, A. Geluk, K. E. van Meijgaarden, S. A. Joosten, D. van Baarle, F. Miedema, W. H. Boom, B. Thiel, J. Sadoff, D. Sizemore, S. Ramachandran, L. Barker, M. Brennan, F. Weichold, S. Muller, L. Geiter, G. Schoolnik, G. Dolganov, T. Van, H. Mayanja-Kizza, M. Joloba, S. Zalwango, M. Nsereko, B. Okwera, H. Kisingo, H. M. Dockrell, S. Smith, P. Gorak-Stolinska, Y.-G. Hur, M. Lalor, J.-S. Lee, A. C. Crampin, N. French, B. Ngwira, A. B. Smith, K. Watkins, L. Ambrose, F. Simukonda, H. Mvula, F. Chilongo, J. Saul, K. Branson, D. Kassa, A. Abebe, T. Mesele, B. Tegbaru, R. Howe, A. Mihret, A. Aseffa, Y. Bekele, R. Iwnetu, M. Tafesse, L. Yamuah, M. Ota, J. Sutherland, P. Hill, R. Adegbola, T. Corrah, M. Antonio, T. Togun, I. Adetifa, S. Donkor, P. Andersen, I. Rosenkrands, M. Doherty, K. Weldingh

Get full text