Editorial: Long-read sequencing—Pitfalls, benefits and success stories by Inken Wohlers, Shilpa Garg, Shilpa Garg, Jayne Y. Hehir-Kwa

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Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology by Ianthe A. E. M. van Belzen, Alexander Schönhuth, Patrick Kemmeren, Jayne Y. Hehir-Kwa

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Platform comparison of detecting copy number variants with microarrays and whole-exome sequencing by Joep de Ligt, Philip M. Boone, Rolph Pfundt, Lisenka E.L.M. Vissers, Nicole de Leeuw, Christine Shaw, Han G. Brunner, James R. Lupski, Joris A. Veltman, Jayne Y. Hehir-Kwa

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Trecode: A FAIR Eco-System for the Analysis and Archiving of Omics Data in a Combined Diagnostic and Research Setting by Hindrik HD Kerstens, Jayne Y Hehir-Kwa, Ellen van de Geer, Chris van Run, Shashi Badloe, Alex Janse, John Baker-Hernandez, Sam de Vos, Douwe van der Leest, Eugène TP Verwiel, Bastiaan BJ Tops, Patrick Kemmeren

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Oncogenic and immunological targets for matched therapy of pediatric blood cancer patients: Dutch iTHER study experience by Judith M. Boer, Uri Ilan, Aurélie Boeree, Karin P. S. Langenberg, Jan Koster, Marco J. Koudijs, Jayne Y. Hehir‐Kwa, Stefan Nierkens, Corinne Rossi, Jan J. Molenaar, Bianca F. Goemans, Monique L. denBoer, C. Michel Zwaan

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Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS by Ianthe A. E. M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Lennart Kester, Jan J. Molenaar, Jules Meijerink, Jarno Drost, Weng Chuan Peng, Hindrik H. D. Kerstens, Bastiaan B. J. Tops, Frank C. P. Holstege, Patrick Kemmeren, Jayne Y. Hehir-Kwa

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M&M: an RNA-seq based pan-cancer classifier for paediatric tumoursResearch in context by Fleur S.A. Wallis, John L. Baker-Hernandez, Marc van Tuil, Claudia van Hamersveld, Marco J. Koudijs, Eugène T.P. Verwiel, Alex Janse, Laura S. Hiemcke-Jiwa, Ronald R. de Krijger, Mariëtte E.G. Kranendonk, Marijn A. Vermeulen, Pieter Wesseling, Uta E. Flucke, Valérie de Haas, Maaike Luesink, Eelco W. Hoving, Josef H. Vormoor, Max M. van Noesel, Jayne Y. Hehir-Kwa, Bastiaan B.J. Tops, Patrick Kemmeren, Lennart A. Kester

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Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes by Michael T Meister, Marian J A Groot Koerkamp, Terezinha de Souza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc van Tuil, Rutger R G Knops, Sheila Terwisscha van Scheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M van Noesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van de Wetering, Ruben van Boxtel, Jarno Drost, Frank C P Holstege

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