Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis by Alexandra Bouscary, Alexandra Bouscary, Cyril Quessada, Cyril Quessada, Althéa Mosbach, Althéa Mosbach, Noëlle Callizot, Michael Spedding, Jean-Philippe Loeffler, Jean-Philippe Loeffler, Alexandre Henriques, Alexandre Henriques, Alexandre Henriques

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Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis by Alexandre Henriques, Alexandre Henriques, Alexandre Henriques, Vincent Croixmarie, Alexandra Bouscary, Alexandra Bouscary, Althéa Mosbach, Althéa Mosbach, Céline Keime, Claire Boursier-Neyret, Bernard Walter, Michael Spedding, Jean-Philippe Loeffler, Jean-Philippe Loeffler

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Skeletal Muscle Metabolism: Origin or Prognostic Factor for Amyotrophic Lateral Sclerosis (ALS) Development? by Cyril Quessada, Alexandra Bouscary, Frédérique René, Cristiana Valle, Alberto Ferri, Shyuan T. Ngo, Jean-Philippe Loeffler

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Alteration of the Neuromuscular Junction and Modifications of Muscle Metabolism in Response to Neuron-Restricted Expression of the CHMP2B^intron5 Mutant in a Mouse Model... by Robin Waegaert, Sylvie Dirrig-Grosch, Haoyi Liu, Marion Boutry, Ping Luan, Jean-Philippe Loeffler, Frédérique René

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Alteration of the Bcl-x/Bax Ratio in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis: Evidence for the Implication of the p53 Signaling Pathway by José-Luis González de Aguilar, Jon W. Gordon, Frédérique René, Marc de Tapia, Bernadette Lutz-Bucher, Christian Gaiddon, Jean-Philippe Loeffler

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Antibody-bound β-amyloid precursor protein stimulates the production of tumor necrosis factor-α and monocyte chemoattractant protein-1 by cortical neurons by Corinne Mbebi, Jose-Luis González de Aguilar, Violaine Sée, Luc Dupuis, Nelly Frossard, Luc Mercken, Laurent Pradier, Yves Larmet, Jean-Philippe Loeffler

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Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosiss⃞ by Anissa Fergani, Hugues Oudart, Jose-Luis Gonzalez De Aguilar, Bastien Fricker, Frédérique René, Jean-François Hocquette, Vincent Meininger, Luc Dupuis, Jean-Philippe Loeffler

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Platelet serotonin level predicts survival in amyotrophic lateral sclerosis. by Luc Dupuis, Odile Spreux-Varoquaux, Gilbert Bensimon, Philippe Jullien, Lucette Lacomblez, François Salachas, Gaëlle Bruneteau, Pierre-François Pradat, Jean-Philippe Loeffler, Vincent Meininger

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Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis by Alexandre Henriques, Mylene Huebecker, Hélène Blasco, Céline Keime, Christian R. Andres, Philippe Corcia, David A. Priestman, Frances M. Platt, Michael Spedding, Jean-Philippe Loeffler

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Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning. by Olivier Bousiges, Romain Neidl, Monique Majchrzak, Marc-Antoine Muller, Alexandra Barbelivien, Anne Pereira de Vasconcelos, Anne Schneider, Jean-Philippe Loeffler, Jean-Christophe Cassel, Anne-Laurence Boutillier

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A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis by Lavinia Palamiuc, Anna Schlagowski, Shyuan T Ngo, Aurelia Vernay, Sylvie Dirrig‐Grosch, Alexandre Henriques, Anne‐Laurence Boutillier, Joffrey Zoll, Andoni Echaniz‐Laguna, Jean‐Philippe Loeffler, Frédérique René

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Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons. by Luc Dupuis, Jose-Luis Gonzalez de Aguilar, Andoni Echaniz-Laguna, Judith Eschbach, Frédérique Rene, Hugues Oudart, Benoit Halter, Caroline Huze, Laurent Schaeffer, Frédéric Bouillaud, Jean-Philippe Loeffler

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Nogo Provides a Molecular Marker for Diagnosis of Amyotrophic Lateral Sclerosis by Luc Dupuis, Jose-Luis Gonzalez de Aguilar, Franck di Scala, Frédérique Rene, Marc de Tapia, Pierre-François Pradat, Lucette Lacomblez, Danielle Seihlan, Rabinder Prinjha, Frank S. Walsh, Vincent Meininger, Jean-Philippe Loeffler

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Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury. by Ghulam Hussain, Florent Schmitt, Alexandre Henriques, Thiebault Lequeu, Frederique Rene, Françoise Bindler, Sylvie Dirrig-Grosch, Hugues Oudart, Lavinia Palamiuc, Marie-Helene Metz-Boutigue, Luc Dupuis, Eric Marchioni, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler

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Blood Cell Palmitoleate-Palmitate Ratio Is an Independent Prognostic Factor for Amyotrophic Lateral Sclerosis. by Alexandre Henriques, Hélène Blasco, Marie-Céline Fleury, Philippe Corcia, Andoni Echaniz-Laguna, Laura Robelin, Gabrielle Rudolf, Thiebault Lequeu, Martine Bergaentzle, Christian Gachet, Pierre-François Pradat, Eric Marchioni, Christian R Andres, Christine Tranchant, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler

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Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age by Judith Eschbach, Jérôme Sinniger, Jamal Bouitbir, Anissa Fergani, Anna-Isabel Schlagowski, Joffrey Zoll, Bernard Geny, Frédérique René, Yves Larmet, Vincent Marion, Robert H. Baloh, Matthew B. Harms, Michael E. Shy, Nadia Messadeq, Patrick Weydt, Jean-Philippe Loeffler, Albert C. Ludolph, Luc Dupuis

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Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1G93A Mice Predates Disease Onset and Is A Promising Therapeutic Target by Silvia Scaricamazza, Illari Salvatori, Giacomo Giacovazzo, Jean Philippe Loeffler, Frederique Renè, Marco Rosina, Cyril Quessada, Daisy Proietti, Constantin Heil, Simona Rossi, Stefania Battistini, Fabio Giannini, Nila Volpi, Frederik J. Steyn, Shyuan T. Ngo, Elisabetta Ferraro, Luca Madaro, Roberto Coccurello, Cristiana Valle, Alberto Ferri

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