Study protocol of the CREDO randomised controlled trial: evaluation of a structured return home consultation for patients suffering from metastaticcancer by Cyrille Delpierre, Laetitia Gimenez, Jean-Pierre Delord, Laurent Molinier, Nadège Costa, Pascale Grosclaude, Marie-Eve Rougé Bugat, Vladimir Druel

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Design and Mechanism of Action of a New Prototype of Combi-Molecule “Programed” to Release Bioactive Species at a pH Range Akin to That of the Tumor Microenvironment by Anne-Laure Larroque-Lombard, Etienne Chatelut, Jean-Pierre Delord, Diane-Charlotte Imbs, Philippe Rochaix, Bertrand Jean-Claude, Ben Allal

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RadioLigand Therapy with [¹⁷⁷Lu]Lu-PSMA-617 for Salivary Gland Cancers: Literature Review and First Compassionate Use in France by Marie Terroir, Chloé Lamesa, Mehdi Krim, Lavinia Vija, Jean-Sébastien Texier, Thibaut Cassou-Mounat, Jean-Pierre Delord, Delphine Vallot, Frédéric Courbon

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A non-inferiority randomized phase III trial of standard immunotherapy by checkpoint inhibitors vs. reduced dose intensity in responding patients with metastatic cancer: the MOIO p... by Gwenaelle Gravis, Patricia Marino, Daniel Olive, Frederique Penault-LLorca, Jean-Pierre Delord, Clotilde Simon, Assia Lamrani-Ghaouti, Renaud Sabatier, Joseph Ciccolini, Jean-Marie Boher

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Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation and predict resistance to immune checkpoint inhibitors in advanced melanoma p... by Carine Dufau, Carine Dufau, Matthieu Genais, Matthieu Genais, Elodie Mucher, Elodie Mucher, Benjamin Jung, Benjamin Jung, Virginie Garcia, Virginie Garcia, Anne Montfort, Anne Montfort, Marie Tosolini, Marie Tosolini, Christopher J. Clarke, Jeffrey A. Medin, Jeffrey A. Medin, Thierry Levade, Thierry Levade, Thierry Levade, Jean-Pierre Delord, Jean-Pierre Delord, Nicolas Meyer, Nicolas Meyer, Nicolas Meyer, Vera Pancaldi, Nathalie Andrieu-Abadie, Nathalie Andrieu-Abadie, Bruno Ségui, Bruno Ségui

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A phase Ib/II trial of capmatinib plus spartalizumab vs. spartalizumab alone in patients with pretreated hepatocellular carcinoma by Armando Santoro, Eric Assenat, Thomas Yau, Jean-Pierre Delord, Michela Maur, Jennifer Knox, Stephane Cattan, Kyung-Hun Lee, Gianluca Del Conte, Christoph Springfeld, Elisa Leo, Alexandros Xyrafas, Lauren Fairchild, Feby Mardjuadi, Stephen L. Chan

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PPARγ activation modulates the balance of peritoneal macrophage populations to suppress ovarian tumor growth and tumor-induced immunosuppression by Hélène Authier, Agnès Coste, Gwenael Ferron, Mélissa Prat, Augustin Le Naour, Kimberley Coulson, Godefroy Jacquemin, Mouna Chirine Rahabi, Jean-Pierre Delord, Bettina Couderc, Clément Blot, Mathilde Romano, Marie-Laure Renoud, Mohamad AlaEddine, Khaddouj Benmoussa, Marie Salon, Mélissa Parny, Lise Lefèvre

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Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers by Juan-Pablo Cerapio, Marion Perrier, Camille-Charlotte Balança, Pauline Gravelle, Fréderic Pont, Christel Devaud, Don-Marc Franchini, Virginie Féliu, Marie Tosolini, Carine Valle, Fréderic Lopez, Anne Quillet-Mary, Loic Ysebaert, Alejandra Martinez, Jean Pierre Delord, Maha Ayyoub, Camille Laurent, Jean-Jacques Fournie

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Circulating CD14high CD16low intermediate blood monocytes as a biomarker of ascites immune status and ovarian cancer progression by Hélène Authier, Agnès Coste, Alejandra Martinez, Gwenael Ferron, Laurence Gladieff, Mélissa Prat, Augustin Le Naour, Kimberley Coulson, Fanny Lemée, Hélène Leray, Godefroy Jacquemin, Mouna Chirine Rahabi, Léa Lemaitre, Jean-Marc Barret, Maha Ayyoub, Jean-Pierre Delord, Isabelle Tabah-Fisch, Jean-François Prost, Bettina Couderc

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Phase Ib study of anti-CSF-1R antibody emactuzumab in combination with CD40 agonist selicrelumab in advanced solid tumor patients by Jean-Marie Michot, Wolfgang Jacob, Francesca Michielin, Martin Weisser, Dmitriy Zamarin, Jean-Pascal Machiels, Anna-Maria Jegg, Dominik Rüttinger, Konstanty Korski, Jean-Pierre Delord, Carlos Gomez-Roca, Tara Mitchell, Gaetan Catala, Lauriane Eberst, Michael A Cannarile, Carl Watson, Galina Babitzki, Irina Klaman, Priscila Teixeira, Sabine Hoves, Carola Ries, Georgina Meneses-Lorente, Randolph Christen, Philippe Cassier

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Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simulta... by Anne Laprie, Soléakhéna Ken, Thomas Filleron, Vincent Lubrano, Laure Vieillevigne, Fatima Tensaouti, Isabelle Catalaa, Sergio Boetto, Jonathan Khalifa, Justine Attal, Guillaume Peyraga, Carlos Gomez-Roca, Emmanuelle Uro-Coste, Georges Noel, Gilles Truc, Marie-Pierre Sunyach, Nicolas Magné, Marie Charissoux, Stéphane Supiot, Valérie Bernier, Muriel Mounier, Muriel Poublanc, Amandine Fabre, Jean-Pierre Delord, Elizabeth Cohen-Jonathan Moyal

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Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component by Benoit Thibault, Fernanda Ramos‐Delgado, Elvire Pons‐Tostivint, Nicole Therville, Celia Cintas, Silvia Arcucci, Stephanie Cassant‐Sourdy, Gabriela Reyes‐Castellanos, Marie Tosolini, Amelie V Villard, Coralie Cayron, Romain Baer, Justine Bertrand‐Michel, Delphine Pagan, Dina Ferreira Da Mota, Hongkai Yan, Chiara Falcomatà, Fabrice Muscari, Barbara Bournet, Jean‐Pierre Delord, Ezra Aksoy, Alice Carrier, Pierre Cordelier, Dieter Saur, Celine Basset, Julie Guillermet‐Guibert

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Randomized, open-label, phase 2 study of nivolumab plus ipilimumab or nivolumab monotherapy in patients with advanced or metastatic solid tumors of high tumor mutational burden by Alexandra Leary, Paolo A Ascierto, Michele Maio, Georgia Kollia, Jennifer Friedmann, Marina Tschaika, Patrick Schöffski, Jonathan Baden, Neeltje Steeghs, Parul Doshi, Massimo Di Nicola, Jean-Pierre Delord, Iwona Lugowska, Mauricio Burotto, David S P Tan, Anthony Gonçalves, Michael Schenker, Ning Huang, Tudor-Eliade Ciuleanu, Martin Richardet, Lorena Lupinacci, Julieta Grasselli, Jacqueline Vuky, Somasekhar Konduru, Sai Vikram Vemula, Ruta Slepetis, Misena Pacius, Quyen Duong

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Randomized phase II study of preoperative afatinib in untreated head and neck cancers: predictive and pharmacodynamic biomarkers of activity by Grégoire Marret, Stéphane Temam, Maud Kamal, Caroline Even, Jean-Pierre Delord, Caroline Hoffmann, Gilles Dolivet, Olivier Malard, Jérôme Fayette, Olivier Capitain, Sébastien Vergez, Lionel Geoffrois, Frédéric Rolland, Philippe Zrounba, Laurent Laccourreye, Esma Saada-Bouzid, Nicolas Aide, Valérie Bénavent, Jerzy Klijianenko, Constance Lamy, Elodie Girard, Sophie Vacher, Julien Masliah-Planchon, Leanne de Koning, Vincent Puard, Edith Borcoman, Marta Jimenez, Ivan Bièche, Jocelyn Gal, Christophe Le Tourneau

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Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma by Juliette Mainguené, Sophie Vacher, Maud Kamal, Abderaouf Hamza, Julien Masliah‐Planchon, Sylvain Baulande, Sabrina Ibadioune, Edith Borcoman, Wulfran Cacheux, Valentin Calugaru, Laura Courtois, Carole Crozes, Marc Deloger, Elodie Girard, Jean‐Pierre Delord, Antoine Dubray‐Vautrin, Linda Larbi Chérif, Celia Dupain, Emmanuelle Jeannot, Jerzy Klijanienko, Sonia Lameiras, Charlotte Lecerf, Anouchka Modesto, Alain Nicolas, Roman Rouzier, Esma Saada‐Bouzid, Pierre Saintigny, Anne Sudaka, Nicolas Servant, Christophe Le Tourneau, Ivan Bièche

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A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors by Stephen L. Chan, Martin Schuler, Yoon-Koo Kang, Chia-Jui Yen, Julien Edeline, Su Pin Choo, Chia-Chi Lin, Takuji Okusaka, Karl-Heinz Weiss, Teresa Macarulla, Stéphane Cattan, Jean-Frederic Blanc, Kyung-Hun Lee, Michela Maur, Shubham Pant, Masatoshi Kudo, Eric Assenat, Andrew X. Zhu, Thomas Yau, Ho Yeong Lim, Jordi Bruix, Andreas Geier, Carmen Guillén-Ponce, Angelica Fasolo, Richard S. Finn, Jia Fan, Arndt Vogel, Shukui Qin, Markus Riester, Vasiliki Katsanou, Monica Chaudhari, Tomoyuki Kakizume, Yi Gu, Diana Graus Porta, Andrea Myers, Jean-Pierre Delord

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