Jeff Wrana

Jeffrey L. Wrana is a Canadian cancer researcher. He is the CIBC Breast Cancer Research Scientist and Mary Janigan Research Chair in Molecular Cancer Therapeutic at Mount Sinai Hospital and University of Toronto (U of T). As a Tier 1 Canada Research Chair in Medical Genetics and Microbiology at U of T, Wrana was elected a Fellow of the Royal Society of Canada. Provided by Wikipedia
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  1. 1
    Recent advances in understanding contextual TGFβ signaling [version 1; referees: 2 approved]

    Recent advances in understanding contextual TGFβ signaling [version 1; referees: 2 approved] by Arshad Ayyaz, Liliana Attisano, Jeffrey L Wrana

    Published 2017-05-01
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  2. 2
    Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap

    Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap by Bita Labibi, Mikhail Bashkurov, Jeffrey L. Wrana, Liliana Attisano

    Published 2020-08-01
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  3. 3
    A critical role for NF2 and the Hippo pathway in branching morphogenesis

    A critical role for NF2 and the Hippo pathway in branching morphogenesis by Antoine Reginensi, Leonie Enderle, Alex Gregorieff, Randy L. Johnson, Jeffrey L. Wrana, Helen McNeill

    Published 2016-08-01
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  4. 4
    Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells

    Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells by Yun-Kyo Kim, Brandon Cho, David P. Cook, Dan Trcka, Jeffrey L. Wrana, Miguel Ramalho-Santos

    Published 2023-01-01
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  5. 5
    Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells

    Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells by Tobias A. Beyer, Alexander Weiss, Yuliya Khomchuk, Kui Huang, Abiodun A. Ogunjimi, Xaralabos Varelas, Jeffrey L. Wrana

    Published 2013-12-01
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  6. 6
    Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.

    Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling. by Tina L Gumienny, Lesley Macneil, Cole M Zimmerman, Huang Wang, Lena Chin, Jeffrey L Wrana, Richard W Padgett

    Published 2010-05-01
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  7. 7
    A lateral signalling pathway coordinates shape volatility during cell migration

    A lateral signalling pathway coordinates shape volatility during cell migration by Liang Zhang, Valbona Luga, Sarah K. Armitage, Martin Musiol, Amy Won, Christopher M. Yip, Sergey V. Plotnikov, Jeffrey L. Wrana

    Published 2016-05-01
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  8. 8
    Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolution.

    Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolution. by Jingjing Li, Yu Liu, Xiaofeng Xin, Taehyung Simon Kim, Eduardo Aguiar Cabeza, Jie Ren, Rasmus Nielsen, Jeffrey L Wrana, Zhaolei Zhang

    Published 2012-01-01
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  9. 9
    Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

    Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse by Michael Fraser, Julie Livingstone, Jeffrey L. Wrana, Antonio Finelli, Housheng Hansen He, Theodorus van der Kwast, Alexandre R. Zlotta, Robert G. Bristow, Paul C. Boutros

    Published 2021-10-01
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  10. 10
    A single cell survey of the microbial impacts on the mouse small intestinal epithelium

    A single cell survey of the microbial impacts on the mouse small intestinal epithelium by Derek K.L. Tsang, Ryan J. Wang, Oliver De Sa, Arshad Ayyaz, Elisabeth G. Foerster, Giuliano Bayer, Shawn Goyal, Daniel Trcka, Bibaswan Ghoshal, Jeffrey L. Wrana, Stephen E. Girardin, Dana J. Philpott

    Published 2022-12-01
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  11. 11
    A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone

    A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone by Junichi Kushioka, Takashi Kaito, Rintaro Okada, Hiroyuki Ishiguro, Zeynep Bal, Joe Kodama, Ryota Chijimatsu, Melanie Pye, Masahiro Narimatsu, Jeffrey L. Wrana, Yasumichi Inoue, Hiroko Ninomiya, Shin Yamamoto, Takashi Saitou, Hideki Yoshikawa, Takeshi Imamura

    Published 2020-11-01
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  12. 12
    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration

    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration by Adrian K.H. Loe, Abilasha Rao-Bhatia, Zhao Wei, Jung-Eun Kim, Bingxin Guan, Yan Qin, Minji Hong, Hyo Sang Kwak, Xiaoyu Liu, Leyi Zhang, Jeffrey L. Wrana, Haiyang Guo, Tae-Hee Kim

    Published 2023-12-01
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  13. 13
    Exosomes Mediate Mobilization of Autocrine Wnt10b to Promote Axonal Regeneration in the Injured CNS

    Exosomes Mediate Mobilization of Autocrine Wnt10b to Promote Axonal Regeneration in the Injured CNS by Nardos G. Tassew, Jason Charish, Alireza P. Shabanzadeh, Valbona Luga, Hidekiyo Harada, Nahal Farhani, Philippe D’Onofrio, Brian Choi, Ahmad Ellabban, Philip E.B. Nickerson, Valerie A. Wallace, Paulo D. Koeberle, Jeffrey L. Wrana, Philippe P. Monnier

    Published 2017-07-01
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  14. 14
    Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways.

    Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways. by Mohamed Abou El Hassan, Katherine Huang, Manoja B K Eswara, Michael Zhao, Lan Song, Tao Yu, Yu Liu, Jeffrey C Liu, Sean McCurdy, Anqi Ma, Joan Wither, Jian Jin, Eldad Zacksenhaus, Jeffrey L Wrana, Rod Bremner

    Published 2015-01-01
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  15. 15
    Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods

    Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods by Joel D. Pearson, Daniel Trcka, Suying Lu, Sharon J. Hyduk, Mark Jen, Marie-Ming Aynaud, J. Javier Hernández, Philippos Peidis, Miriam Barrios-Rodiles, Kin Chan, Jim Woodgett, Tony Mazzulli, Liliana Attisano, Laurence Pelletier, Myron I. Cybulsky, Jeffrey L. Wrana, Rod Bremner

    Published 2021-05-01
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  16. 16
    TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling

    TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling by Jason R. Goldsmith, Nina Spitofsky, Ali Zamani, Ryan Hood, Amanda Boggs, Xinyuan Li, Mingyue Li, Elizabeth Reiner, Arshad Ayyaz, Zienab Etwebi, Ling Lu, Javier Rivera Guzman, Mayassa J. Bou-Dargham, Terry Cathoupolis, Hakon Hakonarson, Honghong Sun, Jeffrey L. Wrana, Michael V. Gonzalez, Youhai H. Chen

    Published 2020-05-01
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  17. 17
    Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis

    Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis by Xiaolin He, Monica F. Tolosa, Tianzhou Zhang, Santosh Kumar Goru, Luisa Ulloa Severino, Paraish S. Misra, Caitríona M. McEvoy, Lauren Caldwell, Stephen G. Szeto, Feng Gao, Xiaolan Chen, Cassandra Atin, Victoria Ki, Noah Vukosa, Catherine Hu, Johnny Zhang, Christopher Yip, Adriana Krizova, Jeffrey L. Wrana, Darren A. Yuen

    Published 2022-02-01
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  18. 18
    p53 promotes revival stem cells in the regenerating intestine after severe radiation injury

    p53 promotes revival stem cells in the regenerating intestine after severe radiation injury by Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis I. Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Constantinos Koumenis, Andy J. Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch

    Published 2024-04-01
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  19. 19
    A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2

    A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 by Marie-Ming Aynaud, J. Javier Hernandez, Seda Barutcu, Ulrich Braunschweig, Kin Chan, Joel D. Pearson, Daniel Trcka, Suzanna L. Prosser, Jaeyoun Kim, Miriam Barrios-Rodiles, Mark Jen, Siyuan Song, Jess Shen, Christine Bruce, Bryn Hazlett, Susan Poutanen, Liliana Attisano, Rod Bremner, Benjamin J. Blencowe, Tony Mazzulli, Hong Han, Laurence Pelletier, Jeffrey L. Wrana

    Published 2021-03-01
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  20. 20
    A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination

    A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination by Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel‐Zarandi, Mariam Iskilova, Miriam Barrios‐Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc‐André Langlois, Anne‐Claude Gingras, Yves Durocher

    Published 2022-01-01
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