Computationally derived points of fragility of a human cascade are consistent with current therapeutic strategies. ανά Deyan Luan, Michael Zai, Jeffrey D Varner

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Computational modeling and analysis of insulin induced eukaryotic translation initiation. ανά Joshua Lequieu, Anirikh Chakrabarti, Satyaprakash Nayak, Jeffrey D Varner

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A test of highly optimized tolerance reveals fragile cell-cycle mechanisms are molecular targets in clinical cancer trials. ανά Satyaprakash Nayak, Saniya Salim, Deyan Luan, Michael Zai, Jeffrey D Varner

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Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1. ανά Russell Gould, David M Bassen, Anirikh Chakrabarti, Jeffrey D Varner, Jonathan Butcher

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Reduced order modeling and analysis of the human complement system. ανά Adithya Sagar, Wei Dai, Mason Minot, Rachel LeCover, Jeffrey D Varner

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Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors. ανά Mengrou Shan, David Dai, Arunodai Vudem, Jeffrey D Varner, Abraham D Stroock

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Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems. ανά Ryan Tasseff, Satyaprakash Nayak, Saniya Salim, Poorvi Kaushik, Noreen Rizvi, Jeffrey D Varner

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Toward a genome scale sequence specific dynamic model of cell-free protein synthesis in Escherichia coli ανά Nicholas Horvath, Michael Vilkhovoy, Joseph A. Wayman, Kara Calhoun, James Swartz, Jeffrey D. Varner

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Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression ανά Holly A. Jensen, Harmony B. Yourish, Rodica P. Bunaciu, Jeffrey D. Varner, Andrew Yen

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Improving designer glycan production in Escherichia coli through model-guided metabolic engineering ανά Joseph A. Wayman, Cameron Glasscock, Thomas J. Mansell, Matthew P. DeLisa, Jeffrey D. Varner

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Differential Contributions of Intrinsic and Extrinsic Pathways to Thrombin Generation in Adult, Maternal and Cord Plasma Samples. ανά Nicklaus T Rice, Fania Szlam, Jeffrey D Varner, Peter S Bernstein, Arthur D Szlam, Kenichi A Tanaka

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Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts. ανά Holly A Jensen, Rodica P Bunaciu, Christopher N Ibabao, Rebecca Myers, Jeffrey D Varner, Andrew Yen

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The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells. ανά Holly A Jensen, Lauren E Styskal, Ryan Tasseff, Rodica P Bunaciu, Johanna Congleton, Jeffrey D Varner, Andrew Yen

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6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. ανά Rodica P Bunaciu, Holly A Jensen, Robert J MacDonald, Dorian H LaTocha, Jeffrey D Varner, Andrew Yen

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Endothelial cells metabolically regulate breast cancer invasion toward a microvessel ανά Matthew L. Tan, Niaa Jenkins-Johnston, Sarah Huang, Brittany Schutrum, Sandra Vadhin, Abhinav Adhikari, Rebecca M. Williams, Warren R. Zipfel, Jan Lammerding, Jeffrey D. Varner, Claudia Fischbach

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