Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network by Rosalind Ramsey-Goldman, Steven Tran, Theresa L Walunas, Abel N Kho, Jennifer A Pacheco, Vesna Mitrovic, Kathryn L Jackson, Noah Forrest, A'lona Furmanchuk

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Impact of CYP2C9‐Interacting Drugs on Warfarin Pharmacogenomics by Saaket Agrawal, Meredith S. Heiss, Remington B. Fenter, Tatiana V. Abramova, Minoli A. Perera, Jennifer A. Pacheco, Maureen E. Smith, Laura J. Rasmussen‐Torvik, Alfred L. George Jr.

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Pathogenic and Uncertain Genetic Variants Have Clinical Cardiac Correlates in Diverse Biobank Participants by Tess D. Pottinger, Megan J. Puckelwartz, Lorenzo L. Pesce, Avery Robinson, Samuel Kearns, Jennifer A. Pacheco, Laura J. Rasmussen‐Torvik, Maureen E. Smith, Rex Chisholm, Elizabeth M. McNally

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Subphenotyping depression using machine learning and electronic health records by Zhenxing Xu, Fei Wang, Prakash Adekkanattu, Budhaditya Bose, Veer Vekaria, Pascal Brandt, Guoqian Jiang, Richard C. Kiefer, Yuan Luo, Jennifer A. Pacheco, Luke V. Rasmussen, Jie Xu, George Alexopoulos, Jyotishman Pathak

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Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans. by Janina M Jeff, Loren L Armstrong, Marylyn D Ritchie, Joshua C Denny, Abel N Kho, Melissa A Basford, Wendy A Wolf, Jennifer A Pacheco, Rongling Li, Rex L Chisholm, Dan M Roden, M Geoffrey Hayes, Dana C Crawford

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Prediction of left ventricular ejection fraction changes in heart failure patients using machine learning and electronic health records: a multi-site study by Prakash Adekkanattu, Luke V. Rasmussen, Jennifer A. Pacheco, Joseph Kabariti, Daniel J. Stone, Yue Yu, Guoqian Jiang, Yuan Luo, Pascal S. Brandt, Zhenxing Xu, Veer Vekaria, Jie Xu, Fei Wang, Natalie C. Benda, Yifan Peng, Parag Goyal, Faraz S. Ahmad, Jyotishman Pathak

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Comparing the effects of four common drug classes on the progression of mild cognitive impairment to dementia using electronic health records by Jie Xu, Fei Wang, Chengxi Zang, Hao Zhang, Kellyann Niotis, Ava L. Liberman, Cynthia M. Stonnington, Makoto Ishii, Prakash Adekkanattu, Yuan Luo, Chengsheng Mao, Luke V. Rasmussen, Zhenxing Xu, Pascal Brandt, Jennifer A. Pacheco, Yifan Peng, Guoqian Jiang, Richard Isaacson, Jyotishman Pathak

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Natural language processing to identify lupus nephritis phenotype in electronic health records by Yu Deng, Jennifer A. Pacheco, Anika Ghosh, Anh Chung, Chengsheng Mao, Joshua C. Smith, Juan Zhao, Wei-Qi Wei, April Barnado, Chad Dorn, Chunhua Weng, Cong Liu, Adam Cordon, Jingzhi Yu, Yacob Tedla, Abel Kho, Rosalind Ramsey-Goldman, Theresa Walunas, Yuan Luo

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Performance of an electronic health record-based phenotype algorithm to identify community associated methicillin-resistant Staphylococcus aureus cases and controls for genetic ass... by Kathryn L. Jackson, Michael Mbagwu, Jennifer A. Pacheco, Abigail S. Baldridge, Daniel J. Viox, James G. Linneman, Sanjay K. Shukla, Peggy L. Peissig, Kenneth M. Borthwick, David A. Carrell, Suzette J. Bielinski, Jacqueline C. Kirby, Joshua C. Denny, Frank D. Mentch, Lyam M. Vazquez, Laura J. Rasmussen-Torvik, Abel N. Kho

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Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions by Jingzhi Yu, Jennifer A. Pacheco, Anika S. Ghosh, Yuan Luo, Chunhua Weng, Ning Shang, Barbara Benoit, David S. Carrell, Robert J. Carroll, Ozan Dikilitas, Robert R. Freimuth, Vivian S. Gainer, Hakon Hakonarson, George Hripcsak, Iftikhar J. Kullo, Frank Mentch, Shawn N. Murphy, Peggy L. Peissig, Andrea H. Ramirez, Nephi Walton, Wei-Qi Wei, Luke V. Rasmussen

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Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. by Jonathan D Mosley, Sara L Van Driest, Emma K Larkin, Peter E Weeke, John S Witte, Quinn S Wells, Jason H Karnes, Yan Guo, Lisa Bastarache, Lana M Olson, Catherine A McCarty, Jennifer A Pacheco, Gail P Jarvik, David S Carrell, Eric B Larson, David R Crosslin, Iftikhar J Kullo, Gerard Tromp, Helena Kuivaniemi, David J Carey, Marylyn D Ritchie, Josh C Denny, Dan M Roden

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Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm. by Yoonjung Yoonie Joo, Jennifer A Pacheco, William K Thompson, Laura J Rasmussen-Torvik, Luke V Rasmussen, Frederick T J Lin, Mariza de Andrade, Kenneth M Borthwick, Erwin Bottinger, Andrew Cagan, David S Carrell, Joshua C Denny, Stephen B Ellis, Omri Gottesman, James G Linneman, Jyotishman Pathak, Peggy L Peissig, Ning Shang, Gerard Tromp, Annapoorani Veerappan, Maureen E Smith, Rex L Chisholm, Andrew J Gawron, M Geoffrey Hayes, Abel N Kho

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GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network by Bahram Namjou, Todd Lingren, Yongbo Huang, Sreeja Parameswaran, Beth L. Cobb, Ian B. Stanaway, John J. Connolly, Frank D. Mentch, Barbara Benoit, Xinnan Niu, Wei-Qi Wei, Robert J. Carroll, Jennifer A. Pacheco, Isaac T. W. Harley, Senad Divanovic, David S. Carrell, Eric B. Larson, David J. Carey, Shefali Verma, Marylyn D. Ritchie, Ali G. Gharavi, Shawn Murphy, Marc S. Williams, David R. Crosslin, Gail P. Jarvik, Iftikhar J. Kullo, Hakon Hakonarson, Rongling Li, The eMERGE Network, Stavra A. Xanthakos, John B. Harley

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Evaluation of the portability of computable phenotypes with natural language processing in the eMERGE network by Jennifer A. Pacheco, Luke V. Rasmussen, Ken Wiley, Thomas Nate Person, David J. Cronkite, Sunghwan Sohn, Shawn Murphy, Justin H. Gundelach, Vivian Gainer, Victor M. Castro, Cong Liu, Frank Mentch, Todd Lingren, Agnes S. Sundaresan, Garrett Eickelberg, Valerie Willis, Al’ona Furmanchuk, Roshan Patel, David S. Carrell, Yu Deng, Nephi Walton, Benjamin A. Satterfield, Iftikhar J. Kullo, Ozan Dikilitas, Joshua C. Smith, Josh F. Peterson, Ning Shang, Krzysztof Kiryluk, Yizhao Ni, Yikuan Li, Girish N. Nadkarni, Elisabeth A. Rosenthal, Theresa L. Walunas, Marc S. Williams, Elizabeth W. Karlson, Jodell E. Linder, Yuan Luo, Chunhua Weng, WeiQi Wei

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Genome-wide study of resistant hypertension identified from electronic health records. by Logan Dumitrescu, Marylyn D Ritchie, Joshua C Denny, Nihal M El Rouby, Caitrin W McDonough, Yuki Bradford, Andrea H Ramirez, Suzette J Bielinski, Melissa A Basford, High Seng Chai, Peggy Peissig, David Carrell, Jyotishman Pathak, Luke V Rasmussen, Xiaoming Wang, Jennifer A Pacheco, Abel N Kho, M Geoffrey Hayes, Martha Matsumoto, Maureen E Smith, Rongling Li, Rhonda M Cooper-DeHoff, Iftikhar J Kullo, Christopher G Chute, Rex L Chisholm, Gail P Jarvik, Eric B Larson, David Carey, Catherine A McCarty, Marc S Williams, Dan M Roden, Erwin Bottinger, Julie A Johnson, Mariza de Andrade, Dana C Crawford

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A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids by Todd L. Edwards, Todd L. Edwards, Todd L. Edwards, Ayush Giri, Ayush Giri, Ayush Giri, Jacklyn N. Hellwege, Jacklyn N. Hellwege, Jacklyn N. Hellwege, Katherine E. Hartmann, Katherine E. Hartmann, Elizabeth A. Stewart, Janina M. Jeff, Michael J. Bray, Sarah A. Pendergrass, Eric S. Torstenson, Eric S. Torstenson, Eric S. Torstenson, Jacob M. Keaton, Jacob M. Keaton, Jacob M. Keaton, Sarah H. Jones, Sarah H. Jones, Radhika P. Gogoi, Helena Kuivaniemi, Helena Kuivaniemi, Kathryn L. Jackson, Abel N. Kho, Iftikhar J. Kullo, Catherine A. McCarty, Hae Kyung Im, Jennifer A. Pacheco, Jyotishman Pathak, Marc S. Williams, Gerard Tromp, Gerard Tromp, Eimear E. Kenny, Eimear E. Kenny, Peggy L. Peissig, Joshua C. Denny, Dan M. Roden, Digna R. Velez Edwards, Digna R. Velez Edwards, Digna R. Velez Edwards

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Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations by Tian Ge, Marguerite R. Irvin, Amit Patki, Vinodh Srinivasasainagendra, Yen-Feng Lin, Hemant K. Tiwari, Nicole D. Armstrong, Barbara Benoit, Chia-Yen Chen, Karmel W. Choi, James J. Cimino, Brittney H. Davis, Ozan Dikilitas, Bethany Etheridge, Yen-Chen Anne Feng, Vivian Gainer, Hailiang Huang, Gail P. Jarvik, Christopher Kachulis, Eimear E. Kenny, Atlas Khan, Krzysztof Kiryluk, Leah Kottyan, Iftikhar J. Kullo, Christoph Lange, Niall Lennon, Aaron Leong, Edyta Malolepsza, Ayme D. Miles, Shawn Murphy, Bahram Namjou, Renuka Narayan, Mark J. O’Connor, Jennifer A. Pacheco, Emma Perez, Laura J. Rasmussen-Torvik, Elisabeth A. Rosenthal, Daniel Schaid, Maria Stamou, Miriam S. Udler, Wei-Qi Wei, Scott T. Weiss, Maggie C. Y. Ng, Jordan W. Smoller, Matthew S. Lebo, James B. Meigs, Nita A. Limdi, Elizabeth W. Karlson

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Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets by Kelsey M. Haas, Michael J. McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun-Young Kim, Thong T. Nguyen, Billy W. Newton, Matthew Urbanowski, Heejin Kim, Michael A. P. Williams, Veronica V. Rezelj, Alexandra Hardy, Andrea Fossati, Erica J. Stevenson, Ellie Sukerman, Tiffany Kim, Sudhir Penugonda, Elena Moreno, Hannes Braberg, Yuan Zhou, Giorgi Metreveli, Bhavya Harjai, Tia A. Tummino, James E. Melnyk, Margaret Soucheray, Jyoti Batra, Lars Pache, Laura Martin-Sancho, Jared Carlson-Stevermer, Alexander S. Jureka, Christopher F. Basler, Kevan M. Shokat, Brian K. Shoichet, Leah P. Shriver, Jeffrey R. Johnson, Megan L. Shaw, Sumit K. Chanda, Dan M. Roden, Tonia C. Carter, Leah C. Kottyan, Rex L. Chisholm, Jennifer A. Pacheco, Maureen E. Smith, Steven J. Schrodi, Randy A. Albrecht, Marco Vignuzzi, Lorena Zuliani-Alvarez, Danielle L. Swaney, Manon Eckhardt, Steven M. Wolinsky, Kris M. White, Judd F. Hultquist, Robyn M. Kaake, Adolfo García-Sastre, Nevan J. Krogan

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