Lassa viral dynamics in non-human primates treated with favipiravir or ribavirin. by Guillaume Lingas, Kyle Rosenke, David Safronetz, Jérémie Guedj

Get full text

Modelling HIV-1 control and remission by Bharadwaj Vemparala, Shreya Chowdhury, Jérémie Guedj, Narendra M. Dixit

Get full text

Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer by Solène Desmée, France Mentré, Christine Veyrat-Follet, Bernard Sébastien, Jérémie Guedj

Get full text

Modelling the effectiveness of antiviral treatment strategies to prevent household transmission of acute respiratory viruses. by Hind Zaaraoui, Clarisse Schumer, Xavier Duval, Bruno Hoen, Lulla Opatowski, Jérémie Guedj

Get full text

Comparison of two‐stage and joint TGI‐OS modeling using data from six atezolizumab clinical studies in patients with metastatic non‐small cell lung cancer by Antonio Gonçalves, Mathilde Marchand, Phyllis Chan, Jin Y. Jin, Jérémie Guedj, René Bruno

Get full text

Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action. by Peter Czuppon, Florence Débarre, Antonio Gonçalves, Olivier Tenaillon, Alan S Perelson, Jérémie Guedj, François Blanquart

Get full text

Mathematical modeling of bacterial kinetics to predict the impact of antibiotic colonic exposure and treatment duration on the amount of resistant enterobacteria excreted. by Thu Thuy Nguyen, Jeremie Guedj, Elisabeth Chachaty, Jean de Gunzburg, Antoine Andremont, France Mentré

Get full text

Tumor growth and overall survival modeling to support decision making in phase Ib/II trials: A comparison of the joint and two‐stage approaches by Mathilde Marchand, Antonio Gonçalves, François Mercier, Pascal Chanu, Jin Y. Jin, Jérémie Guedj, René Bruno

Get full text

Analysis of hepatitis C virus decline during treatment with the protease inhibitor danoprevir using a multiscale model. by Libin Rong, Jeremie Guedj, Harel Dahari, Daniel J Coffield, Micha Levi, Patrick Smith, Alan S Perelson

Get full text

A modelling framework to characterize the impact of antibiotics on the gut microbiota diversity by Carlos Olivares, Etienne Ruppé, Stéphanie Ferreira, Tanguy Corbel, Antoine Andremont, Jean de Gunzburg, Jeremie Guedj, Charles Burdet

Get full text

Quantifying the relationship between SARS-CoV-2 viral load and infectiousness by Aurélien Marc, Marion Kerioui, François Blanquart, Julie Bertrand, Oriol Mitjà, Marc Corbacho-Monné, Michael Marks, Jeremie Guedj

Get full text

Modeling the kinetics of the neutralizing antibody response against SARS-CoV-2 variants after several administrations of Bnt162b2. by Quentin Clairon, Mélanie Prague, Delphine Planas, Timothée Bruel, Laurent Hocqueloux, Thierry Prazuck, Olivier Schwartz, Rodolphe Thiébaut, Jérémie Guedj

Get full text

Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates. by Stéphanie Reynard, Emilie Gloaguen, Nicolas Baillet, Vincent Madelain, Jérémie Guedj, Hervé Raoul, Xavier de Lamballerie, Jimmy Mullaert, Sylvain Baize

Get full text

A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therapy With Direct-Acting Antiviral Agents by Barbara de M. Quintela, Jessica M. Conway, James M. Hyman, Jeremie Guedj, Rodrigo W. dos Santos, Marcelo Lobosco, Alan S. Perelson

Get full text

Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy by Raphaëlle Delattre, Jérémy Seurat, Feyrouz Haddad, Thu-Thuy Nguyen, Baptiste Gaborieau, Rokhaya Kane, Nicolas Dufour, Jean-Damien Ricard, Jérémie Guedj, Laurent Debarbieux

Get full text

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies by Vincent Madelain, Sylvain Baize, Frédéric Jacquot, Stéphanie Reynard, Alexandra Fizet, Stephane Barron, Caroline Solas, Bruno Lacarelle, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie, Jérémie Guedj

Get full text

Quantifying the diversification of hepatitis C virus (HCV) during primary infection: estimates of the in vivo mutation rate. by Ruy M Ribeiro, Hui Li, Shuyi Wang, Mark B Stoddard, Gerald H Learn, Bette T Korber, Tanmoy Bhattacharya, Jeremie Guedj, Erica H Parrish, Beatrice H Hahn, George M Shaw, Alan S Perelson

Get full text

Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials by Vincent Madelain, France Mentré, Sylvain Baize, Xavier Anglaret, Cédric Laouénan, Lisa Oestereich, Thi Huyen Tram Nguyen, Denis Malvy, Géraldine Piorkowski, Frederik Graw, Stephan Günther, Hervé Raoul, Xavier deLamballerie, Jérémie Guedj

Get full text

Modeling the bacterial dynamics in the gut microbiota following an antibiotic‐induced perturbation by Jinju Guk, Antoine Bridier‐Nahmias, Mélanie Magnan, Nathalie Grall, Xavier Duval, Olivier Clermont, Etienne Ruppé, Camille d'Humières, Olivier Tenaillon, Erick Denamur, France Mentré, Jérémie Guedj, Charles Burdet, for the CEREMI study group

Get full text

Impact of variants of concern on SARS-CoV-2 viral dynamics in non-human primates. by Aurélien Marc, Romain Marlin, Flora Donati, Mélanie Prague, Marion Kerioui, Cécile Hérate, Marie Alexandre, Nathalie Dereuddre-Bosquet, Julie Bertrand, Vanessa Contreras, Sylvie Behillil, Pauline Maisonnasse, Sylvie Van Der Werf, Roger Le Grand, Jérémie Guedj

Get full text