Metabolomics as a Promising Resource Identifying Potential Biomarkers for Inflammatory Bowel Disease by Cristina Bauset, Laura Gisbert-Ferrándiz, Jesús Cosín-Roger

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Metabolite Sensing GPCRs: Promising Therapeutic Targets for Cancer Treatment? by Jesús Cosín-Roger, Dolores Ortiz-Masia, Maria Dolores Barrachina, Sara Calatayud

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Is the Macrophage Phenotype Determinant for Fibrosis Development? by Lluis Lis-López, Cristina Bauset, Marta Seco-Cervera, Jesús Cosín-Roger

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Induction of CD36 and thrombospondin-1 in macrophages by hypoxia-inducible factor 1 and its relevance in the inflammatory process. by Dolores Ortiz-Masià, Irene Díez, Sara Calatayud, Carlos Hernández, Jesús Cosín-Roger, Joaquín Hinojosa, Juan V Esplugues, María D Barrachina

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M2 macrophages activate WNT signaling pathway in epithelial cells: relevance in ulcerative colitis. by Jesús Cosín-Roger, Dolores Ortiz-Masiá, Sara Calatayud, Carlos Hernández, Angeles Alvarez, Joaquin Hinojosa, Juan V Esplugues, Maria D Barrachina

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Progastrin represses the alternative activation of human macrophages and modulates their influence on colon cancer epithelial cells. by Carlos Hernández, María Dolores Barrachina, Jesús Cosín-Roger, Dolores Ortiz-Masiá, Ángeles Álvarez, Liria Terrádez, María Jesús Nicolau, Rafael Alós, Juan Vicente Esplugues, Sara Calatayud

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Anti-inflammatory Function of High-Density Lipoproteins via Autophagy of IκB KinaseSummary by Ragam Gerster, Jyrki J. Eloranta, Martin Hausmann, Pedro A. Ruiz, Jesus Cosin-Roger, Anne Terhalle, Urs Ziegler, Gerd A. Kullak-Ublick, Arnold von Eckardstein, Gerhard Rogler

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HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn’s Disease by Marta Gómez-Ferrer, Elena Amaro-Prellezo, Akaitz Dorronsoro, Rafael Sánchez-Sánchez, Ángeles Vicente, Jesús Cosín-Roger, María Dolores Barrachina, María Carmen Baquero, Jaris Valencia, Pilar Sepúlveda

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Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis by Jesus Cosin-Roger, Francisco Canet, Dulce C. Macias-Ceja, Laura Gisbert-Ferrándiz, Dolores Ortiz-Masiá, Juan V. Esplugues, Rafael Alós, Francisco Navarro, María D. Barrachina, Sara Calatayud

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IFNγ-Treated Macrophages Induce EMT through the WNT Pathway: Relevance in Crohn’s Disease by Dulce C. Macias-Ceja, Sandra Coll, Cristina Bauset, Marta Seco-Cervera, Laura Gisbert-Ferrándiz, Francisco Navarro, Jesus Cosin-Roger, Sara Calatayud, María D. Barrachina, Dolores Ortiz-Masia

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Diminished Vitamin D Receptor Protein Levels in Crohn’s Disease Fibroblasts: Effects of Vitamin D by Laura Gisbert-Ferrándiz, Jesús Cosín-Roger, Carlos Hernández, Dulce C. Macias-Ceja, Dolores Ortiz-Masiá, Pedro Salvador, Juan V. Esplugues, Joaquín Hinojosa, Francisco Navarro, Sara Calatayud, María D. Barrachina

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Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development by Dolores Ortiz-Masiá, Laura Gisbert-Ferrándiz, Cristina Bauset, Sandra Coll, Céline Mamie, Michael Scharl, Juan V. Esplugues, Rafael Alós, Francisco Navarro, Jesús Cosín-Roger, María D. Barrachina, Sara Calatayud

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P2X7 Receptor Regulates Collagen Expression in Human Intestinal Fibroblasts: Relevance in Intestinal Fibrosis by Lluis Lis-López, Cristina Bauset, Marta Seco-Cervera, Dulce Macias-Ceja, Francisco Navarro, Ángeles Álvarez, Juan Vicente Esplugues, Sara Calatayud, Maria Dolores Barrachina, Dolores Ortiz-Masià, Jesús Cosín-Roger

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pH-Sensing G Protein-Coupled Receptor OGR1 (GPR68) Expression and Activation Increases in Intestinal Inflammation and Fibrosis by Cheryl de Vallière, Jesus Cosin-Roger, Katharina Baebler, Anja Schoepflin, Céline Mamie, Michelle Mollet, Cordelia Schuler, Susan Bengs, Silvia Lang, Michael Scharl, Klaus Seuwen, Pedro A. Ruiz, Martin Hausmann, Gerhard Rogler

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Gp96 deficiency affects TLR4 functionality and impairs ERK and p38 phosphorylation. by Jesus Cosin-Roger, Marianne R Spalinger, Pedro A Ruiz, Claudia Stanzel, Anne Terhalle, Lutz Wolfram, Hassan Melhem, Kirstin Atrott, Silvia Lang, Isabelle Frey-Wagner, Michael Fried, Michael Scharl, Martin Hausmann, Gerhard Rogler

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SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis by Cristina Bauset, Lluis Lis-Lopez, Sandra Coll, Laura Gisbert-Ferrándiz, Dulce C. Macias-Ceja, Marta Seco-Cervera, Francisco Navarro, Juan V. Esplugues, Sara Calatayud, Dolores Ortiz-Masia, Maria D. Barrachina, Jesús Cosín-Roger

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Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation by Jesus Cosin-Roger, Simona Simmen, Hassan Melhem, Kirstin Atrott, Isabelle Frey-Wagner, Martin Hausmann, Cheryl de Vallière, Marianne R. Spalinger, Patrick Spielmann, Roland H. Wenger, Jonas Zeitz, Stephan R. Vavricka, Gerhard Rogler, Pedro A. Ruiz

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Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal EpitheliumSummary by Simona Simmen, Jesus Cosin-Roger, Hassan Melhem, Nikolaos Maliachovas, Max Maane, Katharina Baebler, Bruce Weder, Chiaki Maeyashiki, Katharina Spanaus, Michael Scharl, Cheryl de Vallière, Jonas Zeitz, Stephan R. Vavricka, Martin Hausmann, Gerhard Rogler, Pedro A. Ruiz

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Hypoxia Reduces the Transcription of Fibrotic Markers in the Intestinal Mucosa by Simona Simmen, Max Maane, Sarah Rogler, Katherina Baebler, Silvia Lang, Jesus Cosin-Roger, Kirstin Atrott, Isabelle Frey-Wagner, Partick Spielmann, Roland H. Wenger, Bruce Weder, Jonas Zeitz, Stephan R. Vavricka, Gerhard Rogler, Cheryl de Vallière, Martin Hausmann, Pedro A. Ruiz

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The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation by Irina V. Tcymbarevich, Jyrki J. Eloranta, Jean-Benoît Rossel, Nicole Obialo, Marianne Spalinger, Jesus Cosin-Roger, Silvia Lang, Gerd A. Kullak-Ublick, Carsten A. Wagner, Michael Scharl, Klaus Seuwen, Pedro A. Ruiz, Gerhard Rogler, Cheryl de Vallière, Benjamin Misselwitz, on behalf of the Swiss IBD Cohort Study Group

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