PB1922: THE FIRST REPORT OF REAL-WORLD OUTCOMES OF ZANUBRUTINIB MONOTHERAPY IN CHRONIC LYMPHOCYTIC LEUKEMIA by Jing Luo, Jiao-Jiao Zhang, Jin Wang, Jian‑qing MI

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P1074: PROGNOSIS ANALYSIS AND A NEW RISK MODEL FOR RELAPSED AND REFRACTORY HODGKIN LYMPHOMA PATIENTS TREATED BY ANTI-PD-1: A REAL-WORLD MULTICENTER RETROSPECTIVE STUDY OF PATIENTS... by Wenyan Yu, Mei Geng, Jie Hao, Zeying Yan, Jian-Qing MI

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P363: A PHASE II STUDY OF FLUMATINIB WITH CHEMOTHERAPY FOR NEWLY DIAGNOSED PH/BCR-ABL1-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA IN ADULTS: UPDATED RESULTS FROM RJ-ALL2020.2A TRIAL by Weiyang Liu, Yuanfang Liu, Yongmei Zhu, Xiangqin Weng, Cheng Wang, Wanyan Ouyang, Jie Xu, Jian‑qing MI, Jin Wang

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P370: EFFICACY AND SAFETY OF THE THIRD-GENERATION TKI OLVEREMBATINIB IN ADULTS PH/BCR-ABL1-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA WITH T315I MUTATION AND RELAPSED/REFRACTORY DISEASE by Weiyang Liu, Yuanfang Liu, Yongmei Zhu, Xiangqin Weng, Cheng Wang, Wanyan Ouyang, Jie Xu, Jin Wang, Jian‑qing MI

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P934: THE EFFECTS OF EXTRAMEDULLARY DISEASE ON OUTCOMES OF PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA by Yi Tao, Shiwei Jin, Yan Wang, Sijie Tang, Yuanfang Liu, Jie Xu, Weiping Zhang, Mengmeng Pan, Jian‑qing MI

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DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1 by Jie Xu, Wu Zhang, Xiao-Jing Yan, Xue-Qiu Lin, Wei Li, Jian-Qing Mi, Jun-Min Li, Jiang Zhu, Zhu Chen, Sai-Juan Chen

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All-trans retinoic acid improves NSD2-mediated RARα phase separation and efficacy of anti-CD38 CAR T-cell therapy in multiple myeloma by Jing Guo, Xin Li, Hongmei Jiang, Jingya Wang, Zhiqiang Liu, Sheng Wang, Ying Xie, Yafei Wang, Mengqi Wang, Ziyi Peng, Yixuan Wang, Meilin Hu, Jian-Qing Mi

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Neutrophil activation and clonal CAR-T re-expansion underpinning cytokine release syndrome during ciltacabtagene autoleucel therapy in multiple myeloma by Shuangshuang Yang, Jie Xu, Yuting Dai, Shiwei Jin, Yan Sun, Jianfeng Li, Chenglin Liu, Xiaolin Ma, Zhu Chen, Lijuan Chen, Jian Hou, Jian-Qing Mi, Sai-Juan Chen

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PD-1 downregulation enhances CAR-T cell antitumor efficiency by preserving a cell memory phenotype and reducing exhaustion by Lei Yu, Yan Wang, Jin Wang, Zhiqiang Liu, Feng Liu, Han Zhao, Yi Tao, Jian-Qing Mi, Nan Xu, Wanyan Ouyang, Shi-Wei Jin, Wei-Yang Liu, Liuqingqing Zhang, Liqing Kang, Yuanfang Liu

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Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity by Yan Sun, Xiu-Na Yang, Shuang-Shuang Yang, Yi-Zhu Lyu, Bing Zhang, Kai-Wen Liu, Na Li, Jia-Chen Cui, Guang-Xiang Huang, Cheng-Lin Liu, Jie Xu, Jian-Qing Mi, Zhu Chen, Xiao-Hu Fan, Sai-Juan Chen, Shuo Chen

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Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia by Li-Jun Peng, Yue-Bo Zhou, Mei Geng, Ekaterina Bourova-Flin, Florent Chuffart, Wei-Na Zhang, Tao Wang, Meng-Qing Gao, Meng-Ping Xi, Zhong-Yi Cheng, Jiao-Jiao Zhang, Yuan-Fang Liu, Bing Chen, Saadi Khochbin, Jin Wang, Sophie Rousseaux, Jian-Qing Mi

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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution by Mengqing Gao, Jin Wang, Sophie Rousseaux, Minjia Tan, Lulu Pan, Lijun Peng, Sisi Wang, Wenqian Xu, Jiayi Ren, Yuanfang Liu, Martin Spinck, Sophie Barral, Tao Wang, Florent Chuffart, Ekaterina Bourova-Flin, Denis Puthier, Sandrine Curtet, Lisa Bargier, Zhongyi Cheng, Heinz Neumann, Jian Li, Yingming Zhao, Jian-Qing Mi, Saadi Khochbin

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P874: LONG-TERM REMISSION AND SURVIVAL IN PATIENTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA AFTER TREATMENT OF LCAR-B38M CAR-T – AT LEAST 5-YEAR FOLLOW-UP IN LEGEND-2 by Jian‑qing MI, Wan‑hong Zhao, Li‑juan Chen, Weijun Fu, Bai‑yan Wang, Jie Xu, Jie Liu, Shi‑wei Jin, Han Zhu, Juan Du, Hua Jiang, Huabin Sun, Yehui Jia, Xiao‑hu Fan, Jian‑yong LI, Jian Hou, Zhu Chen, Wang‑gang Zhang, Ai‑li He, Sai‑juan Chen

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Mutations of Epigenetic Modifier Genes as a Poor Prognostic Factor in Acute Promyelocytic Leukemia Under Treatment With All-Trans Retinoic Acid and Arsenic Trioxide by Yang Shen, Ya-Kai Fu, Yong-Mei Zhu, Yin-Jun Lou, Zhao-Hui Gu, Jing-Yi Shi, Bing Chen, Chao Chen, Hong-Hu Zhu, Jiong Hu, Wei-Li Zhao, Jian-Qing Mi, Li Chen, Hong-Ming Zhu, Zhi-Xiang Shen, Jie Jin, Zhen-Yi Wang, Jun-Min Li, Zhu Chen, Sai-Juan Chen

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Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease by Houfu Leng, Hanlin Zhang, Linsen Li, Shuhao Zhang, Yanping Wang, Selina J. Chavda, Daria Galas-Filipowicz, Hantao Lou, Adel Ersek, Emma V. Morris, Erdinc Sezgin, Yi-Hsuan Lee, Yunsen Li, Ana Victoria Lechuga-Vieco, Mei Tian, Jian-Qing Mi, Kwee Yong, Qing Zhong, Claire M. Edwards, Anna Katharina Simon, Nicole J. Horwood

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Four-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2) by Wan-Hong Zhao, Bai-Yan Wang, Li-Juan Chen, Wei-Jun Fu, Jie Xu, Jie Liu, Shi-Wei Jin, Yin-Xia Chen, Xing-Mei Cao, Yun Yang, Yi-Lin Zhang, Fang-Xia Wang, Peng-Yu Zhang, Bo Lei, Liu-Fang Gu, Jian-Li Wang, Hui Zhang, Ju Bai, Yan Xu, Han Zhu, Juan Du, Hua Jiang, Xiao-Hu Fan, Jian-Yong Li, Jian Hou, Zhu Chen, Wang-Gang Zhang, Jian-Qing Mi, Sai-Juan Chen, Ai-Li He

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Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia by Yuan-Fang Liu, Bai-Yan Wang, Wei-Na Zhang, Jin-Yan Huang, Ben-Shang Li, Ming Zhang, Lu Jiang, Jian-Feng Li, Ming-Jie Wang, Yu-Jun Dai, Zi-Guan Zhang, Qiang Wang, Jie Kong, Bing Chen, Yong-Mei Zhu, Xiang-Qin Weng, Zhi-Xiang Shen, Jun-Min Li, Jin Wang, Xiao-Jing Yan, Yan Li, Ying-Min Liang, Li Liu, Xie-Qun Chen, Wang-Gang Zhang, Jin-Song Yan, Jian-Da Hu, Shu-Hong Shen, Jing Chen, Long-Jun Gu, Deqing Pei, Yongjin Li, Gang Wu, Xin Zhou, Rui-Bao Ren, Cheng Cheng, Jun J. Yang, Kan-Kan Wang, Sheng-Yue Wang, Jinghui Zhang, Jian-Qing Mi, Ching-Hon Pui, Jing-Yan Tang, Zhu Chen, Sai-Juan Chen

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