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FL118, acting as a ‘molecular glue degrader’, binds to, dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and p... by Xiang Ling, Wenjie Wu, Ieman A. M. Aljahdali, Jianqun Liao, Sreevidya Santha, Christos Fountzilas, Patrick M. Boland, Fengzhi Li
Published 2022-05-01
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An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer by Xiang Ling, Wenjie Wu, Chuandong Fan, Chao Xu, Jianqun Liao, Laurie J. Rich, Ruea-Yea Huang, Elizabeth A. Repasky, Xinjiang Wang, Fengzhi Li
Published 2018-10-01
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Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder C... by Sreevidya Santha, Xiang Ling, Ieman A. M. Aljahdali, Sailee S. Rasam, Xue Wang, Jianqun Liao, Jue Wang, Christos Fountzilas, Qingyong Li, Jun Qu, Fengzhi Li
Published 2020-11-01
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