Histone methyltransferase inhibitors: orally bioavailable, fast acting molecules with activity against different human malaria species. by Malmquist, N, Sundriyal, S, Caron, J, Chen, P, Witkowski, B, Menard, D, Suwanarusk, R, Renia, L, Nosten, F, Jiménez-Díaz, M, Angulo-Barturen, I, Martínez, MS, Ferrer, S, Sanz, L, Gamo, F, Wittlin, S, Duffy, S, Avery, V, Ruecker, A, Delves, M, Sinden, R, Fuchter, M, Scherf, A

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum by Vaidya, AB, Morrisey, J, Zhang, Z, Das, S, Daly, T, Otto, T, Spillman, N, Wyvratt, M, Siegl, P, Marfurt, J, Wirjanata, G, Sebayang, B, Price, R, Chatterjee, A, Nagle, A, Stasiak, M, Charman, SA, Angulo-Barturen, I, Ferrer, S, Belén Jiménez-Díaz, M, Martínez, MS, Gamo, F, Avery, V, Ruecker, A, Delves, M, Kirk, K, Berriman, M, Kortagere, S, Burrows, J, Fan, E, Bergman, L

A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malaria by Phillips, M, White, K, Kokkonda, S, Deng, X, White, J, El Mazouni, F, Marsh, K, Tomchick, D, Manjalanagara, K, Rudra, K, Wirjanata, G, Noviyanti, R, Price, R, Marfurt, J, Shackleford, D, Chiu, F, Campbell, M, Jimenez Diaz, M, Ferrer-Bazaga, S, Angulo-Barturen, I, Martínez-Martínez, M, Lafuente-Monasterio, M, Kaminsky, W, Silue, K, Zeeman, A, Kocken, C, Leroy, D, Blasco, B, Rossignol, E, Rueckle, T, Matthews, D, Burrows, J, Waterson, D, Palmer, M, Rathod, P, Charman, S

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling. by Le Bihan, A, de Kanter, R, Angulo-Barturen, I, Binkert, C, Boss, C, Brun, R, Brunner, R, Buchmann, S, Burrows, J, Dechering, K, Delves, M, Ewerling, S, Ferrer, S, Fischli, C, Gamo-Benito, F, Gnädig, N, Heidmann, B, Jiménez-Díaz, M, Leroy, D, Martínez, M, Meyer, S, Moehrle, J, Ng, C, Noviyanti, R, Ruecker, A, Sanz, L, Sauerwein, R, Scheurer, C, Schleiferboeck, S, Sinden, R, Snyder, C, Straimer, J, Wirjanata, G, Marfurt, J, Price, R, Weller, T, Fischli, W, Fidock, D, Clozel, M, Wittlin, S

Quinolone-3-diarylethers: a new class of antimalarial drug. by Nilsen, A, LaCrue, A, White, K, Forquer, I, Cross, R, Marfurt, J, Mather, M, Delves, M, Shackleford, D, Saenz, F, Morrisey, J, Steuten, J, Mutka, T, Li, Y, Wirjanata, G, Ryan, E, Duffy, S, Kelly, J, Sebayang, B, Zeeman, A, Noviyanti, R, Sinden, R, Kocken, C, Price, R, Avery, V, Angulo-Barturen, I, Jiménez-Díaz, M, Ferrer, S, Herreros, E, Sanz, L, Gamo, F, Bathurst, I, Burrows, J, Siegl, P, Guy, R, Winter, R, Vaidya, AB, Charman, SA, Kyle, D, Manetsch, R, Riscoe, M

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance. by O'Neill, P, Amewu, R, Charman, S, Sabbani, S, Gnädig, N, Straimer, J, Fidock, D, Shore, E, Roberts, N, Wong, M, Hong, W, Pidathala, C, Riley, C, Murphy, B, Aljayyoussi, G, Gamo, F, Sanz, L, Rodrigues, J, Cortes, C, Herreros, E, Angulo-Barturén, I, Jiménez-Díaz, M, Bazaga, S, Martínez-Martínez, M, Campo, B, Sharma, R, Ryan, E, Shackleford, D, Campbell, S, Smith, D, Wirjanata, G, Noviyanti, R, Price, R, Marfurt, J, Palmer, M, Copple, I, Mercer, A, Ruecker, A, Delves, M, Sinden, R, Siegl, P, Davies, J, Rochford, R, Kocken, C, Zeeman, A, Nixon, G, Biagini, G, Ward, S

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria by Phillips, M. A., Lotharius, J., Marsh, K., White, J., Dayan, A., White, K. L., Njoroge, J. W., El Mazouni, F., Lao, Y., Kokkonda, S., Tomchick, D. R., Deng, X., Laird, T., Ng, C. L., Fidock, D. A., Wittlin, S., Lafuente-Monasterio, M., Benito, F. J. G., Alonso, L. M. S., Martinez, M. S., Jimenez-Diaz, M. B., Bazaga, S. F., Angulo-Barturen, I., Haselden, J. N., Louttit, J., Cui, Y., Sridhar, A., Zeeman, A.-M., Kocken, C., Sauerwein, R., Dechering, K., Avery, V. M., Duffy, S., Delves, M., Sinden, R., Ruecker, A., Wickham, K. S., Rochford, R., Gahagen, J., Iyer, L., Riccio, E., Mirsalis, J., Bathhurst, I., Rueckle, T., Ding, X., Campo, B., Leroy, D., Rogers, M. J., Rathod, P. K., Burrows, J. N., Charman, S. A., Bhatia, Sangeeta N, March-Riera, Sandra

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