Reactive oxygen species overload promotes apoptosis in JAK2V617F-positive cell lines by João Agostinho Machado-Neto, Fabiola Traina

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Exploring redox vulnerabilities in JAK2V617F-positive cellular models by Keli Lima, Lucia Rossetti Lopes, João Agostinho Machado-Neto

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Perspectives for Targeting Ezrin in Cancer Development and Progression by Jean Carlos Lipreri da Silva, Hugo Passos Vicari, João Agostinho Machado-Neto

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Acute myeloid leukemia-derived bone marrow mesenchymal cells exhibit improved support for leukemic cell proliferation by Mariane Cristina do Nascimento, Diego A. Pereira-Martins, João Agostinho Machado-Neto, Eduardo M. Rego

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The survivin/XIAP suppressant YM155 impairs clonal growth and induces apoptosis in JAK2V617F cells by Jorge Antonio Elias Godoy Carlos, Keli Lima, Eduardo Magalhães Rego, Leticia Veras Costa-Lotufo, João Agostinho Machado-Neto

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Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia by Brunno Gilberto Santos de Macedo, Manuela Albuquerque de Melo, Diego Antonio Pereira-Martins, João Agostinho Machado-Neto, Fabíola Traina

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Differential profile of CDKN1A and TP53 expressions in bone marrow mesenchymal stromal cells from myeloid neoplasms by Matheus Rodrigues Lopes, João Agostinho Machado-Neto, Fabiola Traina, Paula de Melo Campos, Sara Teresinha Olalla Saad, Patricia Favaro

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NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells by Lívia Bassani Lins de Miranda, Keli Lima, Juan Luiz Coelho-Silva, Fabiola Traina, Susumu S. Kobayashi, João Agostinho Machado-Neto

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NT157 exhibits antineoplastic effects by targeting IRS and STAT3/5 signaling in multiple myeloma by Gustavo Nery de Queiroz, Keli Lima, Livia Bassani Lins de Miranda, Eduardo Magalhães Rego, Fabiola Traina, João Agostinho Machado-Neto

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Seriniquinones as Therapeutic Leads for Treatment of BRAF and NRAS Mutant Melanomas by Amanda S. Hirata, Paula Rezende-Teixeira, João Agostinho Machado-Neto, Paula C. Jimenez, James J. La Clair, William Fenical, Leticia V. Costa-Lotufo

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PTK2 and PTPN11 expression in myelodysplastic syndromes by Mariana Lazarini, Joao Agostinho Machado-Neto, Leticia Frohlich Archangelo, Bruna Fernandes Mendes-Silva, Carolina Louzao Bigarella, Fabiola Traina, Sara Teresinha Olalla Saad

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Clinical and molecular profile of a Brazilian cohort of patients with classical BCR-ABL1-negative myeloproliferative neoplasms by Moysés Antonio Porto-Soares, Rafael Daltro de Oliveira, Gabriel Macedo Cortopassi, João Agostinho Machado-Neto, Leonardo Carvalho Palma, Lorena Lobo de Figueiredo-Pontes

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ARHGAP6 transcript levels are associated with molecular risk and impact survival outcomes in acute myeloid leukemia by Jean Carlos Lipreri da Silva, Juan Luiz Coelho-Silva, Hugo Passos Vicari, Keli Lima, Eduardo Magalhães Rego, Fabiola Traina, João Agostinho Machado-Neto

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Two-Dimensional and Spheroid-Based Three-Dimensional Cell Culture Systems: Implications for Drug Discovery in Cancer by Anali del Milagro Bernabe Garnique, Natália Sudan Parducci, Lívia Bassani Lins de Miranda, Bruna Oliveira de Almeida, Leonardo Sanches, João Agostinho Machado-Neto

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P347: PHARMACOLOGICAL EZRIN INHIBITION REDUCES GROWTH, ADHESION, MIGRATION AND REGULATE GENE RELATED TO APOPTOSIS AND CELL CYCLE IN ACUTE LYMPHOBLASTIC LEUKAEMIA by Jean Carlos Lipreri Da Silva, Keli Lima, Mariana Lazarini, Hugo Passos Vicari, Eduardo Magalhães Rego, Benjamin Ede, Anne Ridley, João Agostinho Machado Neto

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Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis by João Agostinho Machado-Neto, Bruna Alves Fenerich, Ana Paula Nunes Rodrigues Alves, Jaqueline Cristina Fernandes, Renata Scopim-Ribeiro, Juan Luiz Coelho-Silva, Fabiola Traina

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Screening for hotspot mutations in PI3K, JAK2, FLT3 and NPM1 in patients with myelodysplastic syndromes by João Agostinho Machado-Neto, Fabiola Traina, Mariana Lazarini, Paula de Melo Campos, Katia Borgia Barbosa Pagnano, Irene Lorand-Metze, Fernando Ferreira Costa, Sara T Olalla Saad

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BNIP3L in myelodysplastic syndromes and acute myeloid leukemia: impact on disease outcome and cellular response to decitabine by Mariana Lazarini, João Agostinho Machado-Neto, Adriana da Silva Santos Duarte, Fernando Vieira Pericole, Karla Priscila Vieira, Fernanda S. Niemann, Marisa Alvarez, Fabiola Traina, Sara Teresinha Olalla Saad

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Comprehensive analysis of the HCK gene in myeloid neoplasms: Insights into biological functions, prognosis, and response to antineoplastic agents by Maria Fernanda Lopes Carvalho, Bruna Oliveira de Almeida, Maura Lima Pereira Bueno, Hugo Passos Vicari, Keli Lima, Eduardo Magalhães Rego, Fernanda Marconi Roversi, João Agostinho Machado-Neto

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PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA by Mariane Cristina Do Nascimento, Diego A Pereira-Martins, Guilherme Augusto Sousa Alcântara, Keli Lima, Hugo Passos Vicari, Marcelo José Pena Ferreira, Leticia Leticia Veras Costa-Lotufo, João Agostinho Machado Neto, Eduardo Magalhães Rego

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