Adaptation to mutational inactivation of an essential gene converges to an accessible suboptimal fitness peak by João V Rodrigues, Eugene I Shakhnovich

Get full text

Development of antibacterial compounds that constrain evolutionary pathways to resistance by Yanmin Zhang, Sourav Chowdhury, João V Rodrigues, Eugene Shakhnovich

Get full text

Empowering drug off-target discovery with metabolic and structural analysis by Sourav Chowdhury, Daniel C. Zielinski, Christopher Dalldorf, Joao V. Rodrigues, Bernhard O. Palsson, Eugene I. Shakhnovich

Get full text

Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics by Eili Y. Klein, Deena Blumenkrantz, Adrian Serohijos, Eugene Shakhnovich, Jeong-Mo Choi, João V. Rodrigues, Brendan D. Smith, Andrew P. Lane, Andrew Feldman, Andrew Pekosz

Get full text