Tackling neurodegeneration in vitro with omics: a path towards new targets and drugs by Caterina Carraro, Caterina Carraro, Jessica V. Montgomery, Julien Klimmt, Dominik Paquet, Dominik Paquet, Joachim L. Schultze, Joachim L. Schultze, Joachim L. Schultze, Marc D. Beyer, Marc D. Beyer, Marc D. Beyer

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Monocyte-derived alveolar macrophages are key drivers of smoke-induced lung inflammation and tissue remodeling by Christian T. Wohnhaas, Kevin Baßler, Carolin K. Watson, Yang Shen, Germán G. Leparc, Cornelia Tilp, Fabian Heinemann, David Kind, Birgit Stierstorfer, Denis Delić, Denis Delić, Thomas Brunner, Florian Gantner, Florian Gantner, Joachim L. Schultze, Joachim L. Schultze, Joachim L. Schultze, Coralie Viollet, Patrick Baum

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Dysregulated Functions of Lung Macrophage Populations in COPD by Theodore S. Kapellos, Kevin Bassler, Anna C. Aschenbrenner, Wataru Fujii, Joachim L. Schultze

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Shiny-Seq: advanced guided transcriptome analysis by Zenitha Sundararajan, Rainer Knoll, Peter Hombach, Matthias Becker, Joachim L. Schultze, Thomas Ulas

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DrugDiff: small molecule diffusion model with flexible guidance towards molecular properties by Marie Oestreich, Erinc Merdivan, Michael Lee, Joachim L. Schultze, Marie Piraud, Matthias Becker

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Comparative Approach to Define Increased Regulatory T Cells in Different Cancer Subtypes by Combined Assessment of CD127 and FOXP3 by Marc Beyer, Sabine Classen, Elmar Endl, Matthias Kochanek, Martin R. Weihrauch, Svenja Debey-Pascher, Percy A. Knolle, Joachim L. Schultze

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Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients by Sander Tuit, Camilla Salvagno, Theodore S. Kapellos, Cheei-Sing Hau, Lea Seep, Marie Oestreich, Kathrin Klee, Karin E. de Visser, Thomas Ulas, Joachim L. Schultze

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IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function by Jan P. Böttcher, Oliver Schanz, Christoph Garbers, Anne Zaremba, Silke Hegenbarth, Christian Kurts, Marc Beyer, Joachim L. Schultze, Wolfgang Kastenmüller, Stefan Rose-John, Percy A. Knolle

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Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics by Mihai G Netea, Katrin Rabold, Gosse J Adema, Anna Aschenbrenner, Christoph Thiele, Collins K Boahen, Alexander Schiltmans, Johannes W A Smit, Joachim L Schultze, Romana T Netea-Maier

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Reconstructing disease dynamics for mechanistic insights and clinical benefit by Amit Frishberg, Neta Milman, Ayelet Alpert, Hannah Spitzer, Ben Asani, Johannes B. Schiefelbein, Evgeny Bakin, Karen Regev-Berman, Siegfried G. Priglinger, Joachim L. Schultze, Fabian J. Theis, Shai S. Shen-Orr

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Differences in the inflammatory proteome of East African and Western European adults and associations with environmental and dietary factors by Godfrey S Temba, Nadira Vadaq, Vesla Kullaya, Tal Pecht, Paolo Lionetti, Duccio Cavalieri, Joachim L Schultze, Reginald Kavishe, Leo AB Joosten, Andre J van der Ven, Blandina T Mmbaga, Mihai G Netea, Quirijn de Mast

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Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates by Niels JM Verstegen, Sabrina Pollastro, Peter-Paul A Unger, Casper Marsman, George Elias, Tineke Jorritsma, Marij Streutker, Kevin Bassler, Kristian Haendler, Theo Rispens, Joachim L Schultze, Anja ten Brinke, Marc Beyer, S Marieke van Ham

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Macrophage-induced enteric neurodegeneration leads to motility impairment during gut inflammation by Mona Breßer, Kevin D Siemens, Linda Schneider, Jonah E Lunnebach, Patrick Leven, Tim R Glowka, Kristin Oberländer, Elena De Domenico, Joachim L Schultze, Joachim Schmidt, Jörg C Kalff, Anja Schneider, Sven Wehner, Reiner Schneider

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SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells by Joshua Jackson, Lena Wischhof, Enzo Scifo, Anna Pellizzer, Yiru Wang, Antonia Piazzesi, Debora Gentile, Sana Siddig, Miriam Stork, Chris E. Hopkins, Kristian Händler, Joachim Weis, Andreas Roos, Joachim L. Schultze, Pierluigi Nicotera, Dan Ehninger, Daniele Bano

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Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state by Caterina Carraro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Arik Horne, Marie Oestreich, Stefanie Warnat-Herresthal, Tim Helbing, Michele De Franco, Kristian Haendler, Sach Mukherjee, Thomas Ulas, Valentina Gandin, Richard Goettlich, Anna C Aschenbrenner, Joachim L Schultze, Barbara Gatto

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Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus ReplicationSummary by Marianna Hösel, Maria Quasdorff, Marc Ringelhan, Hamid Kashkar, Svenja Debey-Pascher, Martin F. Sprinzl, Jan-Hendrik Bockmann, Silke Arzberger, Dennis Webb, Gesa von Olshausen, Achim Weber, Joachim L. Schultze, Hildegard Büning, Mathias Heikenwalder, Ulrike Protzer

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Fighting Post-COVID and ME/CFS – development of curative therapies by Carmen Scheibenbogen, Judith Theresia Bellmann-Strobl, Judith Theresia Bellmann-Strobl, Judith Theresia Bellmann-Strobl, Cornelia Heindrich, Kirsten Wittke, Elisa Stein, Christiana Franke, Harald Prüss, Harald Prüss, Hannah Preßler, Marie-Luise Machule, Heinrich Audebert, Carsten Finke, Hanna Gwendolyn Zimmermann, Hanna Gwendolyn Zimmermann, Hanna Gwendolyn Zimmermann, Birgit Sawitzki, Birgit Sawitzki, Christian Meisel, Christian Meisel, Markus Toelle, Anne Krueger, Anna C. Aschenbrenner, Joachim L. Schultze, Joachim L. Schultze, Joachim L. Schultze, Marc D. Beyer, Marc D. Beyer, Markus Ralser, Markus Ralser, Michael Mülleder, Leif Erik Sander, Frank Konietschke, Friedemann Paul, Friedemann Paul, Friedemann Paul, Silvia Stojanov, Lisa Bruckert, Dennis M. Hedderich, Franziska Knolle, Gabriela Riemekasten, Maria J. G. T. Vehreschild, Oliver A. Cornely, Oliver A. Cornely, Oliver A. Cornely, Uta Behrends, Uta Behrends, Uta Behrends, Susen Burock

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Unveiling the power of high-dimensional cytometry data with cyCONDOR by Charlotte Kröger, Sophie Müller, Jacqueline Leidner, Theresa Kröber, Stefanie Warnat-Herresthal, Jannis Bastian Spintge, Timo Zajac, Anna Neubauer, Aleksej Frolov, Caterina Carraro, DELCODE Study Group, Frank Jessen, Simone Puccio, Anna C. Aschenbrenner, Joachim L. Schultze, Tal Pecht, Marc D. Beyer, Lorenzo Bonaguro

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Machine learning models for outcome prediction in thrombectomy for large anterior vessel occlusion by Omid Shirvani, Stefanie Warnat‐Herresthal, Ivan Savchuk, Felix J. Bode, Louisa Nitsch, Sebastian Stösser, Taraneh Ebrahimi, Niklas vonDanwitz, Hannah Asperger, Julia Layer, Julius Meissner, Christian Thielscher, Franziska Dorn, Nils Lehnen, Joachim L. Schultze, Gabor C. Petzold, Johannes M. Weller, the GSR‐ET Investigators

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Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis by Amir Hossein Kayvanjoo, Iva Splichalova, David Alejandro Bejarano, Hao Huang, Katharina Mauel, Nikola Makdissi, David Heider, Hui Ming Tew, Nora Reka Balzer, Eric Greto, Collins Osei-Sarpong, Kevin Baßler, Joachim L Schultze, Stefan Uderhardt, Eva Kiermaier, Marc Beyer, Andreas Schlitzer, Elvira Mass

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