Joan Heller Brown
Joan Heller Brown is an American pharmacologist. She is Distinguished Professor and Chair of the Department of Pharmacology at UC San Diego School of Medicine. She is known for fundamental contributions to the understanding of G-protein coupled receptors (GPCRs) — molecules that span cell membranes, where they transmit messages between cells and their environments — and how GPCRs regulate cell growth and survival, in healthy and various disease states. Many therapeutic drugs work by influencing GPCRs, thus Heller Brown's discoveries have been crucial to their development. Provided by Wikipedia
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Novel allosteric sites on Ras for lead generation. by Barry J Grant, Suryani Lukman, Harrison J Hocker, Jaqueline Sayyah, Joan Heller Brown, J Andrew McCammon, Alemayehu A Gorfe
Published 2011-01-01
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Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak by Matthias Dewenter, Tilmann Seitz, Julia H. Steinbrecher, B. Daan Westenbrink, Haiyun Ling, Stephan E. Lehnart, Xander H.T. Wehrens, Johannes Backs, Joan Heller Brown, Lars S. Maier, Stefan Neef
Published 2024-08-01
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Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence by Le Yu, Dan Zhou, Guiming Zhang, Zhonglu Ren, Xin Luo, Peng Liu, Steven W. Plouffe, Zhipeng Meng, Toshiro Moroishi, Yilei Li, Yiyue Zhang, Joan Heller Brown, Shuwen Liu, Kun‐Liang Guan
Published 2022-02-01
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A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure by Adam J Pollak, Canzhao Liu, Aparna Gudlur, Joshua E Mayfield, Nancy D Dalton, Yusu Gu, Ju Chen, Joan Heller Brown, Patrick G Hogan, Sandra E Wiley, Kirk L Peterson, Jack E Dixon
Published 2018-12-01
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Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion by Olga Meiri Chaim, Shunichiro Miki, Briana C. Prager, Jianhui Ma, Anthony Y. Jeong, Jacqueline Lara, Nancy K. Tran, Jeffrey M. Smith, Jeremy N. Rich, J. Silvio Gutkind, Shigeki Miyamoto, Frank B. Furnari, Joan Heller Brown
Published 2023-12-01
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Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice by Alex Moshensky, Cameron S Brand, Hasan Alhaddad, John Shin, Jorge A Masso-Silva, Ira Advani, Deepti Gunge, Aditi Sharma, Sagar Mehta, Arya Jahan, Sedtavut Nilaad, Jarod Olay, Wanjun Gu, Tatum Simonson, Daniyah Almarghalani, Josephine Pham, Samantha Perera, Kenneth Park, Rita Al-Kolla, Hoyoung Moon, Soumita Das, Min Kwang Byun, Zahoor Shah, Youssef Sari, Joan Heller Brown, Laura E Crotty Alexander
Published 2022-04-01
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