Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR‐based screens by Jordan Wilson, Joanna I. Loizou

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Leveraging homologous recombination repair deficiency in sarcoma by Dea Slade, Joanna I Loizou

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Interplay between Cellular Metabolism and the DNA Damage Response in Cancer by Amandine Moretton, Joanna I. Loizou

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Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing by Mathilde Meyenberg, Mathilde Meyenberg, Joana Ferreira da Silva, Joana Ferreira da Silva, Joanna I. Loizou, Joanna I. Loizou

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Validating the concept of mutational signatures with isogenic cell models by Xueqing Zou, Michel Owusu, Rebecca Harris, Stephen P. Jackson, Joanna I. Loizou, Serena Nik-Zainal

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Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice by Tianyi Zhang, Kay Penicud, Christopher Bruhn, Joanna I. Loizou, Nnennaya Kanu, Zhao-Qi Wang, Axel Behrens

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High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells by Ruochen Jia, Leon Kutzner, Anna Koren, Kathrin Runggatscher, Peter Májek, André C. Müller, Michael Schuster, Christoph Bock, Joanna I. Loizou, Stefan Kubicek, Robert Kralovics

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Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy by Amandine Moretton, Amandine Moretton, Jana Slyskova, Jana Slyskova, Marwan E. Simaan, Marwan E. Simaan, Marwan E. Simaan, Emili A. Arasa-Verge, Mathilde Meyenberg, Mathilde Meyenberg, D. Alonso Cerrón-Infantes, D. Alonso Cerrón-Infantes, D. Alonso Cerrón-Infantes, D. Alonso Cerrón-Infantes, Miriam M. Unterlass, Miriam M. Unterlass, Miriam M. Unterlass, Miriam M. Unterlass, Joanna I. Loizou, Joanna I. Loizou

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DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation. by Jana Prochazkova, Shinya Sakaguchi, Michel Owusu, Abdelghani Mazouzi, Marc Wiedner, Georgia Velimezi, Martin Moder, Gleb Turchinovich, Anastasiya Hladik, Elisabeth Gurnhofer, Adrian Hayday, Axel Behrens, Sylvia Knapp, Lukas Kenner, Wilfried Ellmeier, Joanna I Loizou

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Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet by Mathilde Meyenberg, Anna Hakobyan, Nikolina Papac-Milicevic, Laura Göderle, Franziska L. Langner, Mateo Markovic, Ji-Hyun Lee, Bon-Kyoung Koo, Georg A. Busslinger, Israel Tojal da Silva, Christoph J. Binder, Jörg Menche, Joanna I. Loizou

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Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia by Martin Moder, Georgia Velimezi, Michel Owusu, Abdelghani Mazouzi, Marc Wiedner, Joana Ferreira da Silva, Lydia Robinson-Garcia, Fiorella Schischlik, Rastislav Slavkovsky, Robert Kralovics, Michael Schuster, Christoph Bock, Trey Ideker, Stephen P. Jackson, Jörg Menche, Joanna I. Loizou

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A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN by Abdelghani Mazouzi, Alexey Stukalov, André C. Müller, Doris Chen, Marc Wiedner, Jana Prochazkova, Shih-Chieh Chiang, Michael Schuster, Florian P. Breitwieser, Andreas Pichlmair, Sherif F. El-Khamisy, Christoph Bock, Robert Kralovics, Jacques Colinge, Keiryn L. Bennett, Joanna I. Loizou

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A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability by Amandine Moretton, Savvas Kourtis, Antoni Gañez Zapater, Chiara Calabrò, Maria Lorena Espinar Calvo, Frédéric Fontaine, Evangelia Darai, Etna Abad Cortel, Samuel Block, Laura Pascual‐Reguant, Natalia Pardo‐Lorente, Ritobrata Ghose, Matthew G Vander Heiden, Ana Janic, André C Müller, Joanna I Loizou, Sara Sdelci

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Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis by Nina K. Serwas, Birgit Hoeger, Rico C. Ardy, Sigrun V. Stulz, Zhenhua Sui, Nima Memaran, Marie Meeths, Ana Krolo, Özlem Yüce Petronczki, Laurène Pfajfer, Tie Z. Hou, Neil Halliday, Elisangela Santos-Valente, Artem Kalinichenko, Alan Kennedy, Emily M. Mace, Malini Mukherjee, Bianca Tesi, Anna Schrempf, Winfried F. Pickl, Joanna I. Loizou, Renate Kain, Bettina Bidmon-Fliegenschnee, Jean-Nicolas Schickel, Salomé Glauzy, Jakob Huemer, Wojciech Garncarz, Elisabeth Salzer, Iro Pierides, Ivan Bilic, Jens Thiel, Peter Priftakis, Pinaki P. Banerjee, Elisabeth Förster-Waldl, David Medgyesi, Wolf-Dietrich Huber, Jordan S. Orange, Eric Meffre, David M. Sansom, Yenan T. Bryceson, Amnon Altman, Kaan Boztug

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