The architecture of prions: how understanding would provide new therapeutic insights by Hasier Eraña, Joaquín Castilla

Get full text

Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism by Natalia Fernández-Borges, Hasier Eraña, Saioa R. Elezgarai, Chafik Harrathi, Mayela Gayosso, Joaquín Castilla

Get full text

A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures by Hasier Eraña, Hasier Eraña, Miguel Ángel Pérez-Castro, Sandra García-Martínez, Sandra García-Martínez, Jorge M. Charco, Jorge M. Charco, Rafael López-Moreno, Carlos M. Díaz-Dominguez, Tomás Barrio, Ezequiel González-Miranda, Ezequiel González-Miranda, Joaquín Castilla, Joaquín Castilla

Get full text

Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie by Juan-Carlos Espinosa, María-Eugenia Herva, Olivier Andréoletti, Danielle Padilla, Caroline Lacroux, Hervé Cassard, Isabelle Lantier, Joaquin Castilla, Juan-María Torres

Get full text

Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies by Jorge M. Charco, Hasier Eraña, Vanessa Venegas, Sandra García-Martínez, Rafael López-Moreno, Ezequiel González-Miranda, Miguel Ángel Pérez-Castro, Joaquín Castilla

Get full text

Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy. by Alicia Otero, Tomás Barrio, Hasier Eraña, Jorge M Charco, Marina Betancor, Carlos M Díaz-Domínguez, Belén Marín, Olivier Andréoletti, Juan M Torres, Qingzhong Kong, Juan J Badiola, Rosa Bolea, Joaquín Castilla

Get full text

An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein. by Claudia Stincardini, Tania Massignan, Silvia Biggi, Saioa R Elezgarai, Valeria Sangiovanni, Ilaria Vanni, Michael Pancher, Valentina Adami, Jorge Moreno, Matteo Stravalaci, Giulia Maietta, Marco Gobbi, Alessandro Negro, Jesús R Requena, Joaquín Castilla, Romolo Nonno, Emiliano Biasini

Get full text

Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions. by Miguel Ángel Pérez-Castro, Hasier Eraña, Enric Vidal, Jorge M Charco, Nuria L Lorenzo, Nuno Gonçalves-Anjo, Josu Galarza-Ahumada, Carlos M Díaz-Domínguez, Patricia Piñeiro, Ezequiel González-Miranda, Samanta Giler, Glenn Telling, Manuel A Sánchez-Martín, Joseba Garrido, Mariví Geijo, Jesús R Requena, Joaquín Castilla

Get full text

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis. by Alejandro M Sevillano, Natalia Fernández-Borges, Neelam Younas, Fei Wang, Saioa R Elezgarai, Susana Bravo, Ester Vázquez-Fernández, Isaac Rosa, Hasier Eraña, David Gil, Sonia Veiga, Enric Vidal, Melissa L Erickson-Beltran, Esteban Guitián, Christopher J Silva, Romolo Nonno, Jiyan Ma, Joaquín Castilla, Jesús R Requena

Get full text

Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents by Alba Marín-Moreno, Sylvie L. Benestad, Tomas Barrio, Laura Pirisinu, Juan Carlos Espinosa, Linh Tran, Alvina Huor, Michele Angelo Di Bari, Hasier Eraña, Ben C. Maddison, Claudia D’Agostino, Natalia Fernández-Borges, Sara Canoyra, Nuria Jerez-Garrido, Joaquín Castilla, John Spiropoulos, Keith Bishop, Kevin C. Gough, Romolo Nonno, Jorn Våge, Olivier Andréoletti, Juan María Torres

Get full text

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions by Hasier Eraña, Cristina Sampedro-Torres-Quevedo, Jorge M. Charco, Carlos M. Díaz-Domínguez, Francesca Peccati, Maitena San-Juan-Ansoleaga, Enric Vidal, Nuno Gonçalves-Anjo, Miguel A. Pérez-Castro, Ezequiel González-Miranda, Patricia Piñeiro, Leire Fernández-Veiga, Josu Galarza-Ahumada, Eva Fernández-Muñoz, Guiomar Perez de Nanclares, Glenn Telling, Mariví Geijo, Gonzalo Jiménez-Osés, Joaquín Castilla

Get full text

Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model by Enric Vidal, Manuel A. Sánchez-Martín, Hasier Eraña, Sonia Pérez Lázaro, Miguel A. Pérez-Castro, Alicia Otero, Jorge M. Charco, Belén Marín, Rafael López-Moreno, Carlos M. Díaz-Domínguez, Mariví Geijo, Montserrat Ordóñez, Guillermo Cantero, Michele di Bari, Nuria L. Lorenzo, Laura Pirisinu, Claudia d’Agostino, Juan María Torres, Vincent Béringue, Glenn Telling, Juan J. Badiola, Martí Pumarola, Rosa Bolea, Romolo Nonno, Jesús R. Requena, Joaquín Castilla

Get full text

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation by Hasier Eraña, Carlos M. Díaz-Domínguez, Jorge M. Charco, Enric Vidal, Ezequiel González-Miranda, Miguel A. Pérez-Castro, Patricia Piñeiro, Rafael López-Moreno, Cristina Sampedro-Torres-Quevedo, Leire Fernández-Veiga, Juan Tasis-Galarza, Nuria L. Lorenzo, Aileen Santini-Santiago, Melisa Lázaro, Sandra García-Martínez, Nuno Gonçalves-Anjo, Maitena San-Juan-Ansoleaga, Josu Galarza-Ahumada, Eva Fernández-Muñoz, Samanta Giler, Mikel Valle, Glenn C. Telling, Mariví Geijó, Jesús R. Requena, Joaquín Castilla

Get full text

A tetracationic porphyrin with dual anti-prion activity by Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Gabriele Giachin, Laura Tapella, Liliana Comerio, Elena Restelli, Ilaria Raimondi, Saioa R. Elezgarai, Federica De Leo, Giacomo Quilici, Lorenzo Taiarol, Marvin Oldrati, Nuria L. Lorenzo, Sandra García-Martínez, Alfredo Cagnotto, Jacopo Lucchetti, Marco Gobbi, Ilaria Vanni, Romolo Nonno, Michele A. Di Bari, Mark D. Tully, Valentina Cecatiello, Giuseppe Ciossani, Sebastiano Pasqualato, Eelco Van Anken, Mario Salmona, Joaquín Castilla, Jesús R. Requena, Stefano Banfi, Giovanna Musco, Roberto Chiesa

Get full text

A tetracationic porphyrin with dual anti-prion activity by Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Gabriele Giachin, Laura Tapella, Liliana Comerio, Elena Restelli, Ilaria Raimondi, Saioa R. Elezgarai, Federica De Leo, Giacomo Quilici, Lorenzo Taiarol, Marvin Oldrati, Nuria L. Lorenzo, Sandra García-Martínez, Alfredo Cagnotto, Jacopo Lucchetti, Marco Gobbi, Ilaria Vanni, Romolo Nonno, Michele A. Di Bari, Mark D. Tully, Valentina Cecatiello, Giuseppe Ciossani, Sebastiano Pasqualato, Eelco Van Anken, Mario Salmona, Joaquín Castilla, Jesús R. Requena, Stefano Banfi, Giovanna Musco, Roberto Chiesa

Get full text