The architecture of prions: how understanding would provide new therapeutic insights by Hasier Eraña, Joaquín Castilla

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Detection of PrPres in genetically susceptible fetuses from sheep with natural scrapie. by María Carmen Garza, Natalia Fernández-Borges, Rosa Bolea, Juan José Badiola, Joaquín Castilla, Eva Monleón

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A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures by Hasier Eraña, Hasier Eraña, Miguel Ángel Pérez-Castro, Sandra García-Martínez, Sandra García-Martínez, Jorge M. Charco, Jorge M. Charco, Rafael López-Moreno, Carlos M. Díaz-Dominguez, Tomás Barrio, Ezequiel González-Miranda, Ezequiel González-Miranda, Joaquín Castilla, Joaquín Castilla

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Accelerated high fidelity prion amplification within and across prion species barriers. by Kristi M Green, Joaquín Castilla, Tanya S Seward, Dana L Napier, Jean E Jewell, Claudio Soto, Glenn C Telling

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Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease by Alicia Otero, Marina Betancor, Hasier Eraña, Natalia Fernández Borges, José J. Lucas, Juan José Badiola, Joaquín Castilla, Rosa Bolea

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Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria by Ganeko Bernardo-Seisdedos, Jorge M. Charco, Itxaso SanJuan, Sandra García-Martínez, Pedro Urquiza, Hasier Eraña, Joaquín Castilla, Oscar Millet

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Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie by Juan-Carlos Espinosa, María-Eugenia Herva, Olivier Andréoletti, Danielle Padilla, Caroline Lacroux, Hervé Cassard, Isabelle Lantier, Joaquin Castilla, Juan-María Torres

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Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies by Jorge M. Charco, Hasier Eraña, Vanessa Venegas, Sandra García-Martínez, Rafael López-Moreno, Ezequiel González-Miranda, Miguel Ángel Pérez-Castro, Joaquín Castilla

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Unraveling the key to the resistance of canids to prion diseases. by Natalia Fernández-Borges, Beatriz Parra, Enric Vidal, Hasier Eraña, Manuel A Sánchez-Martín, Jorge de Castro, Saioa R Elezgarai, Martí Pumarola, Tomás Mayoral, Joaquín Castilla

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Detection of Pathognomonic Biomarker PrP^Sc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases by Hasier Eraña, Jorge M. Charco, Ezequiel González-Miranda, Sandra García-Martínez, Rafael López-Moreno, Miguel A. Pérez-Castro, Carlos M. Díaz-Domínguez, Adrián García-Salvador, Joaquín Castilla

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Chronic wasting disease in bank voles: characterisation of the shortest incubation time model for prion diseases. by Michele Angelo Di Bari, Romolo Nonno, Joaquín Castilla, Claudia D'Agostino, Laura Pirisinu, Geraldina Riccardi, Michela Conte, Juergen Richt, Robert Kunkle, Jan Langeveld, Gabriele Vaccari, Umberto Agrimi

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Spontaneous Generation of Infectious Prion Disease in Transgenic Mice by Juan-María Torres, Joaquín Castilla, Belén Pintado, Alfonso Gutiérrez-Adan, Olivier Andréoletti, Patricia Aguilar-Calvo, Ana-Isabel Arroba, Beatriz Parra-Arrondo, Isidro Ferrer, Jorge Manzanares, Juan-Carlos Espinosa

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Cerebrospinal Fluid and Plasma Small Extracellular Vesicles and miRNAs as Biomarkers for Prion Diseases by Óscar López-Pérez, David Sanz-Rubio, Adelaida Hernaiz, Marina Betancor, Alicia Otero, Joaquín Castilla, Olivier Andréoletti, Juan José Badiola, Pilar Zaragoza, Rosa Bolea, Janne M. Toivonen, Inmaculada Martín-Burriel

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Transgenic Mouse Bioassay: Evidence That Rabbits Are Susceptible to a Variety of Prion Isolates. by Enric Vidal, Natalia Fernández-Borges, Belén Pintado, Hasier Eraña, Montserrat Ordóñez, Mercedes Márquez, Francesca Chianini, Dolors Fondevila, Manuel A Sánchez-Martín, Olivier Andreoletti, Mark P Dagleish, Martí Pumarola, Joaquín Castilla

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Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy. by Alicia Otero, Tomás Barrio, Hasier Eraña, Jorge M Charco, Marina Betancor, Carlos M Díaz-Domínguez, Belén Marín, Olivier Andréoletti, Juan M Torres, Qingzhong Kong, Juan J Badiola, Rosa Bolea, Joaquín Castilla

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Elements modulating the prion species barrier and its passage consequences. by Juan-Maria Torres, Juan-Carlos Espinosa, Patricia Aguilar-Calvo, María-Eugenia Herva, Aroa Relaño-Ginés, Ana Villa-Diaz, Mónica Morales, Beatriz Parra, Elia Alamillo, Alejandro Brun, Joaquín Castilla, Susana Molina, Steve A C Hawkins, Olivier Andreoletti

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Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy. by Mark P Dagleish, Stuart Martin, Philip Steele, Jeanie Finlayson, Samantha L Eaton, Sílvia Sisó, Paula Stewart, Natalia Fernández-Borges, Scott Hamilton, Yvonne Pang, Francesca Chianini, Hugh W Reid, Wilfred Goldmann, Lorenzo González, Joaquín Castilla, Martin Jeffrey

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An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein. by Claudia Stincardini, Tania Massignan, Silvia Biggi, Saioa R Elezgarai, Valeria Sangiovanni, Ilaria Vanni, Michael Pancher, Valentina Adami, Jorge Moreno, Matteo Stravalaci, Giulia Maietta, Marco Gobbi, Alessandro Negro, Jesús R Requena, Joaquín Castilla, Romolo Nonno, Emiliano Biasini

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Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear by Natalia C. Ferreira, Jorge M. Charco, Jakob Plagenz, Christina D. Orru, Nathanial D. Denkers, Michael A. Metrick, Andrew G. Hughson, Karen A. Griffin, Brent Race, Edward A. Hoover, Joaquín Castilla, Tracy A. Nichols, Michael W. Miller, Byron Caughey

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Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease by Teresa Ximelis, Alba Marín-Moreno, Juan Carlos Espinosa, Hasier Eraña, Jorge M. Charco, Isabel Hernández, Carmen Riveira, Daniel Alcolea, Eva González-Roca, Iban Aldecoa, Laura Molina-Porcel, Piero Parchi, Marcello Rossi, Joaquín Castilla, Raquel Ruiz-García, Ellen Gelpi, Juan María Torres, Raquel Sánchez-Valle

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