Detection of minimal residual disease in acute myeloid leukemia: evaluating utility and challenges by Noemí Álvarez, Noemí Álvarez, Alejandro Martín, Alejandro Martín, Sara Dorado, Sara Dorado, Rafael Colmenares, Laura Rufián, Laura Rufián, Margarita Rodríguez, Margarita Rodríguez, Alicia Giménez, Laura Carneros, Ricardo Sanchez, Gonzalo Carreño, Inmaculada Rapado, Yanira Heredia, Joaquín Martínez-López, Joaquín Martínez-López, Joaquín Martínez-López, Joaquín Martínez-López, Santiago Barrio, Santiago Barrio, Santiago Barrio, Rosa Ayala, Rosa Ayala, Rosa Ayala, Rosa Ayala

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Impact of IPSS-M implementation in real-life clinical practice by Irene Zamanillo, Maria Poza, Rosa Ayala, Inmaculada Rapado, Joaquín Martinez-Lopez, Maria Teresa Cedena

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β-Thalassaemia Major in a Spanish Patient due to a Compound Heterozygosity for CD39 C→T/−28 A→C by Soledad Gamarra, Guillermo Garcia-Effron, Carmen Monteserin, Isabel Lopez-Villar, Florinda Gilsanz, Joaquín Martinez-Lopez

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Protein Carbonylation and Lipid Peroxidation in Hematological Malignancies by Alba Rodríguez-García, Roberto García-Vicente, María Luz Morales, Alejandra Ortiz-Ruiz, Joaquín Martínez-López, María Linares

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Long-Term Human Hematopoietic Stem Cell Culture in Microdroplets by Pilar Carreras, Itziar González, Miguel Gallardo, Alejandra Ortiz-Ruiz, Maria Luz Morales, Jessica Encinas, Joaquín Martínez-López

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Overcoming tumor resistance mechanisms in CAR-NK cell therapy by Antonio Valeri, Antonio Valeri, Almudena García-Ortiz, Almudena García-Ortiz, Eva Castellano, Eva Castellano, Laura Córdoba, Laura Córdoba, Elena Maroto-Martín, Elena Maroto-Martín, Jessica Encinas, Jessica Encinas, Alejandra Leivas, Alejandra Leivas, Paula Río, Joaquín Martínez-López, Joaquín Martínez-López

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Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model by Brenna E. Swift, Brent A. Williams, Yoko Kosaka, Xing-Hua Wang, Jeffrey A. Medin, Sowmya Viswanathan, Joaquin Martinez-Lopez, Armand Keating

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Cost-effectiveness of Ruxolitinib vs Best Available Therapy in the Treatment of Myelofibrosis in Spain by María Teresa Gómez-Casares, Juan Carlos Hernández-Boluda, Antonio Jiménez-Velasco, Joaquin Martínez-López, María Giovanna Ferrario, Irmina Gozalbo, Joana Gostkorzewicz, Rudi Subirá

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Multidisciplinary management in chronic myeloid leukemia improves cardiovascular risk measured by SCORE by Alberto Blanco Sánchez, Rodrigo Gil Manso, Gonzalo Carreño-Tarragona, Diana Paredes Ruiz, Jesús González Olmedo, Joaquín Martínez-López, Carmen Díaz Pedroche, Rosa Ayala

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Uncovering therapeutic opportunities in the clinical development of antibody‐drug conjugates by Cristina Nieto‐Jiménez, Adrián Sanvicente, Cristina Díaz‐Tejeiro, Víctor Moreno, Alfonso lopez deSá, Emiliano Calvo, Joaquín Martínez‐López, Pedro Pérez‐Segura, Alberto Ocaña

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Isolation of Functional SARS-CoV-2 Antigen-Specific T-Cells with Specific Viral Cytotoxic Activity for Adoptive Therapy of COVID-19 by Estéfani García-Ríos, Alejandra Leivas, Francisco J. Mancebo, Laura Sánchez-Vega, Diego Lanzarot, José María Aguado, Joaquín Martínez-López, María Liz Paciello, Pilar Pérez-Romero

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Results from HARMONY: an open-label, multicenter, 2-arm, phase 1b, dose-finding study assessing the safety and efficacy of the oral combination of ruxolitinib and buparlisib in pat... by Simon T. Durrant, Arnon Nagler, Paola Guglielmelli, David Lavie, Philipp le Coutre, Heinz Gisslinger, Charles Chuah, Margherita Maffioli, Savita Bharathy, Tuochuan Dong, Monika Wroclawska, Joaquin Martinez Lopez

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Regulation of miRNA expression by α4β1 integrin‐dependent multiple myeloma cell adhesion by Yaiza Rodríguez‐García, Mónica Martínez‐Moreno, Lola Alonso, Anna Sánchez‐Vencells, Alicia Arranz, Roger Dagà‐Millán, Silvia Sevilla‐Movilla, Antonio Valeri, Joaquin Martínez‐López, Joaquin Teixidó

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Clinical Outcomes of Patients with Multiple Myeloma after Daratumumab Failure by Irene Zamanillo, Lucia Medina de Alba, Rodrigo Gil, Rosalia de la Puerta, Rafael Alonso, Ana Jimenez-Ubieto, Maria Teresa Cedena, Maria Calbacho, Rosa Ayala, Joaquin Martinez-Lopez

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P702: APPLICATION OF NEXT GENERATION SEQUENCING (NGS) FOR MINIMAL RESIDUAL DISEASE (MRD) AND CHIMERISM MONITORING IN MYELODYSPLASTIC SYNDROME (MDS) AFTER ALLOGENIC STEM CELL TRANSP... by Irene Zamanillo, Santiago Barrio, Alejandro Martin, Sara Dorado, Yanira Heredia, Margarita Rodriguez, Inmaculada Rapado, Ana Isabel Jimenez Ubieto, Rosa Ayala Diaz, Joaquín Martinez-Lopez, Maria Teresa Cedena Romero

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Phase 1b Study of Isatuximab in Combination With Bortezomib, Cyclophosphamide, and Dexamethasone in Newly Diagnosed, Transplant-ineligible Multiple Myeloma Patients by Enrique M. Ocio, Sara Bringhen, Joaquin Martinez-Lopez, Jesus San-Miguel, Stefania Oliva, Paula Rodriguez-Otero, Nadia Le Roux, Yvonne Dong, Severine Doroumian, Sandrine Macé, Maria-Victoria Mateos

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Monitoring of clonal evolution of acute myeloid leukemia identifies the leukemia subtype, clinical outcome and potential new drug targets for post-remission strategies or relapse by Esther Onecha, Inmaculada Rapado, María Luz Morales, Gonzalo Carreño-Tarragona, Pilar Martinez-Sanchez, Xabier Gutierrez, José María Sáchez Pina, María Linares, Miguel Gallardo, Joaquín Martinez-López, Rosa Ayala

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30‐Minute infusion of isatuximab in patients with newly diagnosed multiple myeloma: Results of a Phase 1b study analysis by Enrique M. Ocio, Aurore Perrot, Philippe Moreau, Maria‐Victoria Mateos, Sara Bringhen, Joaquín Martínez‐López, Lionel Karlin, Song‐Yau Wang, Corina Oprea, Yi Li, Ercem Kodas, Jesus San‐Miguel

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PB1781: THE APPLICATION OF CF-DNA FOR NGS MRD STUDIES IN PATIENTS WITH LMA IMPROVES THE SENSITIVITY OF THE METHOD WITH RESPECT TO CTC. by Noemí Álvarez Sánchez-Redondo, Alejandro Martin, Sara Dorado, Laura Rufián, Margarita Rodriguez, Yanira Heredia, Maria Calbacho Robles, Maria Teresa Cedena Romero, Joaquín Martinez-Lopez, Santiago Barrio, Rosa Ayala Diaz

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Ruxolitinib in combination with prednisone and nilotinib exhibit synergistic effects in human cells lines and primary cells from myeloproliferative neoplasms by Alicia Arenas Cortés, Rosa Ayala Diaz, Pilar Hernández-Campo, Julián Gorrochategui, Daniel Primo, Alicia Robles, María Luz Morales, Joan Ballesteros, Inmaculada Rapado, Miguel Gallardo, María Linares, Joaquín Martínez-López

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