Controlled Delivery of Vancomycin via Charged Hydrogels. by Carl T Gustafson, Felix Boakye-Agyeman, Cassandra L Brinkman, Joel M Reid, Robin Patel, Zeljko Bajzer, Mahrokh Dadsetan, Michael J Yaszemski

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Inhibiting the growth of pancreatic adenocarcinoma in vitro and in vivo through targeted treatment with designer gold nanotherapeutics. by Rachel A Kudgus, Annamaria Szabolcs, Jameel Ahmad Khan, Chad A Walden, Joel M Reid, J David Robertson, Resham Bhattacharya, Priyabrata Mukherjee

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CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants by Lingxin Zhang, Vivekananda Sarangi, Irene Moon, Jia Yu, Duan Liu, Sandhya Devarajan, Joel M. Reid, Krishna R. Kalari, Liewei Wang, Richard Weinshilboum

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Model‐informed approach to support pediatric dosing for the pan‐PI3K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors by Peter N. Morcos, Jan Schlender, Rolf Burghaus, Jonathan Moss, Adam Lloyd, Barrett H. Childs, Margaret E. Macy, Joel M. Reid, John Chung, Dirk Garmann

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Modulating pharmacokinetics, tumor uptake and biodistribution by engineered nanoparticles. by Rochelle R Arvizo, Oscar R Miranda, Daniel F Moyano, Chad A Walden, Karuna Giri, Resham Bhattacharya, J David Robertson, Vincent M Rotello, Joel M Reid, Priyabrata Mukherjee

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Pharmacological and pharmacokinetic profile of the novel ocular hypotensive prodrug CKLP1 in Dutch-belted pigmented rabbits. by Uttio Roy Chowdhury, Rachel A Kudgus, Tommy A Rinkoski, Bradley H Holman, Cindy K Bahler, Cheryl R Hann, Joel M Reid, Peter I Dosa, Michael P Fautsch

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Non-chemotherapy adjuvant agents in TP53 mutant Ewing sarcoma by Jin-Ah Kim, Kenneth A. Crawford, Piero A. Spada, Leah R. Martin, Jiaqi Zhang, Rain Wong, Joel M. Reid, Clinton F. Stewart, Timothy M. Frank, Qianqian Liu, Joel E. Michalek, Charles Keller

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A Phase I Study of the Oral Dual-Acting Pan-PI3K/mTOR Inhibitor Bimiralisib in Patients with Advanced Solid Tumors by Filip Janku, Grace M. Choong, Mateusz Opyrchal, Afshin Dowlati, Cinta Hierro, Jordi Rodon, Andreas Wicki, Martin D. Forster, Sarah P. Blagden, Jun Yin, Joel M. Reid, Helene Muller, Natasa Cmiljanovic, Vladimir Cmiljanovic, Alex A. Adjei

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A phase 2 and pharmacological study of sapanisertib in patients with relapsed and/or refractory acute lymphoblastic leukemia by Aref Al‐Kali, Ibrahim Aldoss, Pamela J. Atherton, Carrie A. Strand, Bijal Shah, Jonathan Webster, Bhavana Bhatnagar, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Sarah A. Buhrow, Jianping Kong, Joel M. Reid, Alex A. Adjei, Scott H. Kaufmann

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Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer by Swaathi Jayaraman, Xinyan Wu, Krishna R. Kalari, Xiaojia Tang, Mary J. Kuffel, Elizabeth S. Bruinsma, Shahrzad Jalali, Kevin L. Peterson, Cristina Correia, Rachel A. Kudgus, Scott H. Kaufmann, Santosh Renuse, James N. Ingle, Joel M. Reid, Matthew M. Ames, Alan P. Fields, Matthew J. Schellenberg, John R. Hawse, Akhilesh Pandey, Matthew P. Goetz

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Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide) by Julianna D. Zeidler, Claudia C.S. Chini, Karina S. Kanamori, Sonu Kashyap, Jair M. Espindola-Netto, Katie Thompson, Gina Warner, Fernanda S. Cabral, Thais R. Peclat, Lilian Sales Gomez, Sierra A. Lopez, Miles K. Wandersee, Renee A. Schoon, Kimberly Reid, Keir Menzies, Felipe Beckedorff, Joel M. Reid, Sebastian Brachs, Ralph G. Meyer, Mirella L. Meyer-Ficca, Eduardo Nunes Chini

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Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer by Swaathi Jayaraman, Xiaonan Hou, Mary J. Kuffel, Vera J. Suman, Tanya L. Hoskin, Kathryn E. Reinicke, David G. Monroe, Krishna R. Kalari, Xiaojia Tang, Megan A. Zeldenrust, Jingfei Cheng, Elizabeth S. Bruinsma, Sarah A. Buhrow, Renee M. McGovern, Stephanie L. Safgren, Chad A. Walden, Jodi M. Carter, Joel M. Reid, James N. Ingle, Matthew M. Ames, John R. Hawse, Matthew P. Goetz

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Combined Antitumor Effect of the Serine Protease Urokinase Inhibitor Upamostat and the Sphingosine Kinase 2 Inhibitor Opaganib on Cholangiocarcinoma Patient-Derived Xenografts by Faizal Z. Asumda, Nellie A. Campbell, Mohamed A. Hassan, Reza Fathi, Daniella F. Vasquez Rico, Melanie Kiem, Ethan V. Vang, Yo Han Kim, Xin Luo, Daniel R. O’Brien, Sarah A. Buhrow, Joel M. Reid, Michael J. Moore, Vered Katz Ben-Yair, Mark L. Levitt, Jennifer L. Leiting, Amro M. Abdelrahman, Xinli Zhu, Fabrice Lucien, Mark J. Truty, Lewis R. Roberts

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Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice by Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal Dehankar, Cory C. Funk, Jordan Wilkins, Anna Stepanova, Tara O’Hagan, Alexander Galkin, Jarred Nesbitt, Xiujuan Zhu, Utkarsh Tripathi, Slobodan Macura, Tamar Tchkonia, Tamar Pirtskhalava, James L. Kirkland, Rachel A. Kudgus, Renee A. Schoon, Joel M. Reid, Yu Yamazaki, Takahisa Kanekiyo, Song Zhang, Emirhan Nemutlu, Petras Dzeja, Adam Jaspersen, Ye In Christopher Kwon, Michael K. Lee, Eugenia Trushina

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Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice by Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal Dehankar, Cory C. Funk, Jordan Wilkins, Anna Stepanova, Tara O’Hagan, Alexander Galkin, Jarred Nesbitt, Xiujuan Zhu, Utkarsh Tripathi, Slobodan Macura, Tamar Tchkonia, Tamar Pirtskhalava, James L. Kirkland, Rachel A. Kudgus, Renee A. Schoon, Joel M. Reid, Yu Yamazaki, Takahisa Kanekiyo, Song Zhang, Emirhan Nemutlu, Petras Dzeja, Adam Jaspersen, Ye In Christopher Kwon, Michael K. Lee, Eugenia Trushina

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