ImageBox 2 – Efficient and rapid access of image tiles from whole-slide images using serverless HTTP range requests by Erich Bremer, Joel Saltz, Jonas S Almeida

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Serverless OpenHealth at data commons scale—traversing the 20 million patient records of New York’s SPARCS dataset in real-time by Jonas S. Almeida, Janos Hajagos, Joel Saltz, Mary Saltz

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Dynamic Decision and Data-Driven Strategies for the Optimal Management of Subsurface Geo-Systems by Manish Parashar, Hector Klie, Tahsin Kurc, Umit Catalyurek, Joel Saltz, Mary F. Wheeler

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Twenty years of digital pathology: An overview of the road travelled, what is on the horizon, and the emergence of vendor-neutral archives by Liron Pantanowitz, Ashish Sharma, Alexis B Carter, Tahsin Kurc, Alan Sussman, Joel Saltz

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Investigation of commonly used aortic aneurysm growth rate metrics: Comparing their suitability for clinical and research applications. by Kayley Abell-Hart, Janos Hajagos, Victor Garcia, James Kaan, Wei Zhu, Mary Saltz, Joel Saltz, Apostolos Tassiopoulos

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Deep Learning-Based Mapping of Tumor Infiltrating Lymphocytes in Whole Slide Images of 23 Types of Cancer by Shahira Abousamra, Rajarsi Gupta, Le Hou, Rebecca Batiste, Tianhao Zhao, Anand Shankar, Arvind Rao, Chao Chen, Dimitris Samaras, Tahsin Kurc, Joel Saltz

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A National Strategy to Develop Pragmatic Clinical Trials Infrastructure by Thomas W. Concannon, Jeanne‐Marie Guise, Rowena J. Dolor, Paul Meissner, Sean Tunis, Jerry A. Krishnan, Wilson D. Pace, Joel Saltz, William R. Hersh, Lloyd Michener, Timothy S. Carey

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A data model and database for high-resolution pathology analytical image informatics by Fusheng Wang, Jun Kong, Lee Cooper, Tony Pan, Tahsin Kurc, Wenjin Chen, Ashish Sharma, Cristobal Niedermayr, Tae W Oh, Daniel Brat, Alton B Farris, David J Foran, Joel Saltz

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Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images by Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc, Joel Saltz

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Publisher Correction to: Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images by Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc, Joel Saltz

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NCI Workshop Report: Clinical and Computational Requirements for Correlating Imaging Phenotypes with Genomics Signatures by Rivka Colen, Ian Foster, Robert Gatenby, Mary Ellen Giger, Robert Gillies, David Gutman, Matthew Heller, Rajan Jain, Anant Madabhushi, Subha Madhavan, Sandy Napel, Arvind Rao, Joel Saltz, James Tatum, Roeland Verhaak, Gary Whitman

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Association of Proteinuria and Hematuria with Acute Kidney Injury and Mortality in Hospitalized Patients with COVID-19 by Imran Chaudhri, Richard Moffitt, Erin Taub, Raji R. Annadi, Minh Hoai, Olena Bolotova, Jeanwoo Yoo, Simrat Dhaliwal, Haseena Sahib, Farah Daccueil, Janos Hajagos, Mary Saltz, Joel Saltz, Sandeep K. Mallipattu, Farrukh M. Koraishy

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Robust Image Population Based Stain Color Normalization: How Many Reference Slides Are Enough? by Jose L. Agraz, Caleb M. Grenko, Andrew A. Chen, Angela N. Viaene, MacLean D. Nasrallah, Sarthak Pati, Tahsin Kurc, Joel Saltz, Michael D. Feldman, Hamed Akbari, Parth Sharma, Russell T. Shinohara, Spyridon Bakas

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Spatial Characterization of Tumor-Infiltrating Lymphocytes and Breast Cancer Progression by Danielle J. Fassler, Luke A. Torre-Healy, Rajarsi Gupta, Alina M. Hamilton, Soma Kobayashi, Sarah C. Van Alsten, Yuwei Zhang, Tahsin Kurc, Richard A. Moffitt, Melissa A. Troester, Katherine A. Hoadley, Joel Saltz

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Privacy‐preserving record linkage across disparate institutions and datasets to enable a learning health system: The national COVID cohort collaborative (N3C) experience by Umberto Tachinardi, Shaun J. Grannis, Sam G. Michael, Leonie Misquitta, Jayme Dahlin, Usman Sheikh, Abel Kho, Jasmin Phua, Sara S. Rogovin, Benjamin Amor, Maya Choudhury, Philip Sparks, Amin Mannaa, Saad Ljazouli, Joel Saltz, Fred Prior, Ahmen Baghal, Kenneth Gersing, Peter J. Embi

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Quality improvements in radiation oncology clinical trials by Koren Smith, Kenneth Ulin, Michael Knopp, Stephan Kry, Ying Xiao, Mark Rosen, Jeff Michalski, Matthew Iandoli, Fran Laurie, Jean Quigley, Heather Reifler, Juan Santiago, Kathleen Briggs, Shawn Kirby, Kate Schmitter, Fred Prior, Joel Saltz, Ashish Sharma, Maryann Bishop-Jodoin, Janaki Moni, M. Giulia Cicchetti, Thomas J. FitzGerald

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Radiation Oncology: Future Vision for Quality Assurance and Data Management in Clinical Trials and Translational Science by Linda Ding, Carla Bradford, I-Lin Kuo, Yankhua Fan, Kenneth Ulin, Abdulnasser Khalifeh, Suhong Yu, Fenghong Liu, Jonathan Saleeby, Harry Bushe, Koren Smith, Camelia Bianciu, Salvatore LaRosa, Fred Prior, Joel Saltz, Ashish Sharma, Mark Smyczynski, Maryann Bishop-Jodoin, Fran Laurie, Matthew Iandoli, Janaki Moni, M. Giulia Cicchetti, Thomas J. FitzGerald

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A pathologist-annotated dataset for validating artificial intelligence: A project description and pilot study by Sarah N Dudgeon, Si Wen, Matthew G Hanna, Rajarsi Gupta, Mohamed Amgad, Manasi Sheth, Hetal Marble, Richard Huang, Markus D Herrmann, Clifford H Szu, Darick Tong, Bruce Werness, Evan Szu, Denis Larsimont, Anant Madabhushi, Evangelos Hytopoulos, Weijie Chen, Rajendra Singh, Steven N Hart, Ashish Sharma, Joel Saltz, Roberto Salgado, Brandon D Gallas

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Segmentation and Classification in Digital Pathology for Glioma Research: Challenges and Deep Learning Approaches by Tahsin Kurc, Spyridon Bakas, Spyridon Bakas, Spyridon Bakas, Xuhua Ren, Aditya Bagari, Alexandre Momeni, Yue Huang, Lichi Zhang, Ashish Kumar, Marc Thibault, Qi Qi, Qian Wang, Avinash Kori, Olivier Gevaert, Yunlong Zhang, Dinggang Shen, Dinggang Shen, Mahendra Khened, Xinghao Ding, Ganapathy Krishnamurthi, Jayashree Kalpathy-Cramer, James Davis, Tianhao Zhao, Rajarsi Gupta, Rajarsi Gupta, Joel Saltz, Keyvan Farahani

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Automated digital TIL analysis (ADTA) adds prognostic value to standard assessment of depth and ulceration in primary melanoma by Michael R. Moore, Isabel D. Friesner, Emanuelle M. Rizk, Benjamin T. Fullerton, Manas Mondal, Megan H. Trager, Karen Mendelson, Ijeuru Chikeka, Tahsin Kurc, Rajarsi Gupta, Bethany R. Rohr, Eric J. Robinson, Balazs Acs, Rui Chang, Harriet Kluger, Bret Taback, Larisa J. Geskin, Basil Horst, Kevin Gardner, George Niedt, Julide T. Celebi, Robyn D. Gartrell-Corrado, Jane Messina, Tammie Ferringer, David L. Rimm, Joel Saltz, Jing Wang, Rami Vanguri, Yvonne M. Saenger

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