A Multimodal Platform for Simultaneous T-cell Imaging, Defined Activation, and Mechanobiological Characterization by Martin Fölser, Viktoria Motsch, René Platzer, Johannes B. Huppa, Gerhard J. Schütz

Get full text

Adjuvants and Vaccines Used in Allergen-Specific Immunotherapy Induce Neutrophil Extracellular Traps by Jasmine Karacs, Manuel Reithofer, Claudia Kitzmüller, Markus Kraller, Stefanie Schmalz, Sonja Bleichert, Johannes B. Huppa, Hannes Stockinger, Barbara Bohle, Beatrice Jahn-Schmid

Get full text

Advanced Quantification of Receptor–Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy by Lukas Schrangl, Vanessa Mühlgrabner, René Platzer, Florian Kellner, Josephine Wieland, Reinhard Obst, José L. Toca-Herrera, Johannes B. Huppa, Gerhard J. Schütz, Janett Göhring

Get full text

Breakthrough Infections in SARS-CoV-2-Vaccinated Multiple Myeloma Patients Improve Cross-Protection against Omicron Variants by Angelika Wagner, Erika Garner-Spitzer, Claudia Auer, Pia Gattinger, Ines Zwazl, René Platzer, Maria Orola-Taus, Peter Pichler, Fabian Amman, Andreas Bergthaler, Johannes B. Huppa, Hannes Stockinger, Christoph C. Zielinski, Rudolf Valenta, Michael Kundi, Ursula Wiedermann

Get full text

CXCR4 has a dual role in improving the efficacy of BCMA-redirected CAR-NK cells in multiple myeloma by Michael W. Moles, Henry Erdlei, Lutz Menzel, Marialucia Massaro, Agnese Fiori, Mario Bunse, Moritz Schrimpf, Kerstin Gerlach, Venugopal Gudipati, John Reiser, Ketan Mathavan, Jodie P. Goodrich, Johannes B. Huppa, Jan Krönke, Bahram Valamehr, Uta E. Höpken, Armin Rehm

Get full text

CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer by Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, Francesca Nonateli, Timo Peters, Tassilo L.A. Wachsmann, Mercedes Hernandez-Rueda, Johannes B. Huppa, Gerhard J. Schütz, Eva Sevcsik, Beatriz Moreno, Fernando Pastor

Get full text

CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition by Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B. Huppa, Sonia Guedan

Get full text

CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation by Torsten Tonn, Hans Klingemann, Winfried S Wels, Jiri Eitler, Natalie Wotschel, Laurent Boissel, Michael Bachmann, Wiebke Rackwitz, Venugopal Gudipati, Nivedha Murali Shankar, Anastasia Sidorenkova, Johannes B Huppa, Paola Ortiz-Montero, Corinna Opitz, Stephan R Künzel, Susanne Michen, Achim Temme, Liliana Rodrigues Loureiro, Anja Feldmann

Get full text

Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells a... by Erika Garner-Spitzer, Angelika Wagner, Venugopal Gudipati, Anna-Margarita Schoetta, Maria Orola-Taus, Michael Kundi, Renate Kunert, Patrick Mayrhofer, Johannes B. Huppa, Hannes Stockinger, Rita Carsetti, Pia Gattinger, Rudolf Valenta, Bernhard Kratzer, Al Nasar Ahmed Sehgal, Winfried F. Pickl, Walter Reinisch, Gottfried Novacek, Ursula Wiedermann

Get full text

The frequency of differentiated CD3+CD27-CD28- T cells predicts response to CART cell therapy in diffuse large B-cell lymphoma by Nina Worel, Katharina Grabmeier-Pfistershammer, Bernhard Kratzer, Martina Schlager, Andreas Tanzmann, Arno Rottal, Ulrike Körmöczi, Edit Porpaczy, Philipp B. Staber, Cathrin Skrabs, Harald Herkner, Venugopal Gudipati, Johannes B. Huppa, Benjamin Salzer, Manfred Lehner, Nora Saxenhuber, Eleonora Friedberg, Philipp Wohlfarth, Georg Hopfinger, Werner Rabitsch, Ingrid Simonitsch-Klupp, Ulrich Jäger, Winfried F. Pickl

Get full text

Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances by Anna Ohradanova-Repic, Christian Machacek, Celine Charvet, Celine Charvet, Celine Charvet, Franck Lager, Franck Lager, Franck Lager, Delphine Le Roux, Delphine Le Roux, Delphine Le Roux, René Platzer, Vladimir Leksa, Vladimir Leksa, Goran Mitulovic, Thomas R. Burkard, Gerhard J. Zlabinger, Michael B. Fischer, Michael B. Fischer, Vincent Feuillet, Vincent Feuillet, Vincent Feuillet, Gilles Renault, Gilles Renault, Gilles Renault, Stephan Blüml, Miroslav Benko, Miloslav Suchanek, Johannes B. Huppa, Takami Matsuyama, Artur Cavaco-Paulo, Georges Bismuth, Georges Bismuth, Georges Bismuth, Hannes Stockinger

Get full text