Mechanisms of isoform specific Rap2 signaling during enterocytic brush border formation. by Lucas J M Bruurs, Johannes L Bos

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The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation. by Sarah V Consonni, Patricia M Brouwer, Eleonora S van Slobbe, Johannes L Bos

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Rap1 and Rap2 antagonistically control endothelial barrier resistance. by Willem-Jan Pannekoek, Jelena R Linnemann, Patricia M Brouwer, Johannes L Bos, Holger Rehmann

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A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization. by Lucas J M Bruurs, Mirjam C van der Net, Susan Zwakenberg, Fried J T Zwartkruis, Johannes L Bos

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Structure-guided design of selective Epac1 and Epac2 agonists. by Frank Schwede, Daniela Bertinetti, Carianne N Langerijs, Michael A Hadders, Hans Wienk, Johanne H Ellenbroek, Eelco J P de Koning, Johannes L Bos, Friedrich W Herberg, Hans-Gottfried Genieser, Richard A J Janssen, Holger Rehmann

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Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening by Carla S Verissimo, René M Overmeer, Bas Ponsioen, Jarno Drost, Sander Mertens, Ingrid Verlaan-Klink, Bastiaan van Gerwen, Marieke van der Ven, Marc van de Wetering, David A Egan, René Bernards, Hans Clevers, Johannes L Bos, Hugo J Snippert

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Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer by Sander Mertens, Maarten A. Huismans, Carla S. Verissimo, Bas Ponsioen, Rene Overmeer, Natalie Proost, Olaf van Tellingen, Marieke van de Ven, Harry Begthel, Sylvia F. Boj, Hans Clevers, Jeanine M.L. Roodhart, Johannes L. Bos, Hugo J.G. Snippert

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