Plant Glycosides and Glycosidases: A Treasure-Trove for Therapeutics by Kassiani Kytidou, Marta Artola, Marta Artola, Herman S. Overkleeft, Johannes M. F. G. Aerts

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Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses by Fredj Ben Bdira, Marta Artola, Herman S. Overkleeft, Marcellus Ubbink, Johannes M.F.G. Aerts

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Glycosphingolipids and Infection. Potential New Therapeutic Avenues by Johannes M. F. G. Aerts, M. Artola, M. van Eijk, M. J. Ferraz, R. G. Boot

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Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions by Ken Kok, Kimberley C. Zwiers, Rolf G. Boot, Hermen S. Overkleeft, Johannes M. F. G. Aerts, Marta Artola

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Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival. by Tanit L Gabriel, Mina Mirzaian, Berend Hooibrink, Roelof Ottenhoff, Cindy van Roomen, Johannes M F G Aerts, Marco van Eijk

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a-Synuclein and lipids in erythrocytes of Gaucher disease carriers and patients before and after enzyme replacement therapy by Marina Moraitou, Georgios Sotiroudis, Nikolaos Papagiannakis, Maria M. J. Ferraz, Aristotelis Xenakis, Johannes M. F. G. Aerts, Leonidas Stefanis, Helen Michelakakis

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a-Synuclein and lipids in erythrocytes of Gaucher disease carriers and patients before and after enzyme replacement therapy. by Marina Moraitou, Georgios Sotiroudis, Nikolaos Papagiannakis, Maria M J Ferraz, Aristotelis Xenakis, Johannes M F G Aerts, Leonidas Stefanis, Helen Michelakakis

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Persistent bone disease in adult type 1 Gaucher disease despite increasing doses of enzyme replacement therapy by Maaike de Fost, Carel J.M. van Noesel, Johannes M.F.G. Aerts, Mario Maas, Ruud G. Pöll, Carla E.M. Hollak

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Low frequency maintenance therapy with imiglucerase in adult type I Gaucher disease: a prospective randomized controlled trial by Maaike de Fost, Johannes M.F.G. Aerts, Johanna E.M. Groener, Mario Maas, Erik M. Akkerman, Maaike G. Wiersma, Carla E.M. Hollak

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Label-free LC-MSe in tissue and serum reveals protein networks underlying differences between benign and malignant serous ovarian tumors. by Wouter Wegdam, Carmen A Argmann, Gertjan Kramer, Johannes P Vissers, Marrije R Buist, Gemma G Kenter, Johannes M F G Aerts, Danielle Meijer, Perry D Moerland

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Therapeutic challenges in two adolescent male patients with Fabry disease and high antibody titres by Aizeddin A. Mhanni, Christiane Auray-Blais, Michel Boutin, Alie Johnston, Kaye LeMoine, Jill Patterson, Johannes M.F.G. Aerts, Michael L. West, Cheryl Rockman-Greenberg

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Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities[S] by Jeroen van Smeden, Hanin Al-Khakany, Yichen Wang, Dani Visscher, Nicole Stephens, Samira Absalah, Herman S. Overkleeft, Johannes M.F.G. Aerts, Alain Hovnanian, Joke A. Bouwstra

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Renal involvement in a patient with the chronic visceral subtype of acid sphingomyelinase deficiency resembles Fabry disease by Eline C. B. Eskes, Martijn J. C. van derLienden, Joris J. T. H. Roelofs, Liffert Vogt, Johannes M. F. G. Aerts, Jan Aten, Carla E. M. Hollak

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Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease by Simon Wheeler, Per Haberkant, Meenakshi Bhardwaj, Paige Tongue, Maria J. Ferraz, David Halter, Hein Sprong, Ralf Schmid, Johannes M.F.G. Aerts, Nikol Sullo, Dan J. Sillence

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Treatment of Fabry disease: outcome of a comparative trial with agalsidase alfa or beta at a dose of 0.2 mg/kg. by Anouk C Vedder, Gabor E Linthorst, Gunnar Houge, Johannna E M Groener, Els E Ormel, Berto J Bouma, Johannes M F G Aerts, Asle Hirth, Carla E M Hollak

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Accuracy and Reproducibility in Quantification of Plasma Protein Concentrations by Mass Spectrometry without the Use of Isotopic Standards. by Gertjan Kramer, Yvonne Woolerton, Jan P van Straalen, Johannes P C Vissers, Nick Dekker, James I Langridge, Robert J Beynon, Dave Speijer, Auguste Sturk, Johannes M F G Aerts

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N-Azidoacetylmannosamine-mediated chemical tagging of gangliosides by Anton P. Bussink, Paul F. van Swieten, Karen Ghauharali, Saskia Scheij, Marco van Eijk, Tom Wennekes, Gijs A. van der Marel, Rolf G. Boot, Johannes M.F.G. Aerts, Herman S. Overkleeft

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Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector by Maria Dahl, Emma M.K. Smith, Sarah Warsi, Michael Rothe, Maria J. Ferraz, Johannes M.F.G. Aerts, Azadeh Golipour, Claudia Harper, Richard Pfeifer, Daniella Pizzurro, Axel Schambach, Chris Mason, Stefan Karlsson

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Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes. by Wouter W Kallemeijn, Saskia Scheij, Sascha Hoogendoorn, Martin D Witte, Daniela Herrera Moro Chao, Cindy P A A van Roomen, Roelof Ottenhoff, Herman S Overkleeft, Rolf G Boot, Johannes M F G Aerts

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Effects of switching from a reduced dose imiglucerase to velaglucerase in type 1 Gaucher disease: clinical and biochemical outcomes by Laura van Dussen, Timothy M. Cox, Erik J. Hendriks, Elizabeth Morris, Erik M. Akkerman, Mario Maas, Johanna E. M. Groener, Johannes M.F.G. Aerts, Patrick B. Deegan, Carla E. M. Hollak

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