High-throughput functional analysis of regulatory variants using a massively parallel reporter assay by Kate Delfosse, Chiara Gerhardinger, John L. Rinn, Philipp G. Maass

Get full text

Enhancers in the Peril lincRNA locus regulate distant but not local genes by Abigail F. Groff, A. Rasim Barutcu, Jordan P. Lewandowski, John L. Rinn

Get full text

Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking by Pornchai Kaewsapsak, David Michael Shechner, William Mallard, John L Rinn, Alice Y Ting

Get full text

Anatomic demarcation by positional variation in fibroblast gene expression programs. by John L Rinn, Chanda Bondre, Hayes B Gladstone, Patrick O Brown, Howard Y Chang

Get full text

In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation by Daniel Andergassen, Zachary D Smith, Jordan P Lewandowski, Chiara Gerhardinger, Alexander Meissner, John L Rinn

Get full text

A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus by A. Rasim Barutcu, Philipp G. Maass, Jordan P. Lewandowski, Catherine L. Weiner, John L. Rinn

Get full text

Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo by Thomas A Carter, Manvendra Singh, Gabrijela Dumbović, Jason D Chobirko, John L Rinn, Cédric Feschotte

Get full text

Cis and trans effects differentially contribute to the evolution of promoters and enhancers by Kaia Mattioli, Winona Oliveros, Chiara Gerhardinger, Daniel Andergassen, Philipp G. Maass, John L. Rinn, Marta Melé

Get full text

Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells by A. Rasim Barutcu, Gabriel Elizalde, Alfredo E. Gonzalez, Kartik Soni, John L. Rinn, Amy J. Wagers, Albert E. Almada

Get full text

Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency. by Jeffrey R Haswell, Kaia Mattioli, Chiara Gerhardinger, Philipp G Maass, Daniel J Foster, Paola Peinado, Xiaofeng Wang, Pedro P Medina, John L Rinn, Frank J Slack

Get full text

Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency by Jeffrey R. Haswell, Kaia Mattioli, Chiara Gerhardinger, Philipp G. Maass, Daniel J. Foster, Paola Peinado, Xiaofeng Wang, Pedro P. Medina, John L. Rinn, Frank J. Slack

Get full text

Resolving mechanisms of immune‐mediated disease in primary CD4 T cells by Christophe Bourges, Abigail F Groff, Oliver S Burren, Chiara Gerhardinger, Kaia Mattioli, Anna Hutchinson, Theodore Hu, Tanmay Anand, Madeline W Epping, Chris Wallace, Kenneth GC Smith, John L Rinn, James C Lee

Get full text

In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements by Abigail F. Groff, Diana B. Sanchez-Gomez, Marcela M.L. Soruco, Chiara Gerhardinger, A. Rasim Barutcu, Eric Li, Lara Elcavage, Olivia Plana, Lluvia V. Sanchez, James C. Lee, Martin Sauvageau, John L. Rinn

Get full text

Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques by Luisa Santus, Maria Sopena-Rios, Raquel García-Pérez, Aaron E. Lin, Gordon C. Adams, Kayla G. Barnes, Katherine J. Siddle, Shirlee Wohl, Ferran Reverter, John L. Rinn, Richard S. Bennett, Lisa E. Hensley, Pardis C. Sabeti, Marta Melé

Get full text

The reality of pervasive transcription. by Michael B Clark, Paulo P Amaral, Felix J Schlesinger, Marcel E Dinger, Ryan J Taft, John L Rinn, Chris P Ponting, Peter F Stadler, Kevin V Morris, Antonin Morillon, Joel S Rozowsky, Mark B Gerstein, Claes Wahlestedt, Yoshihide Hayashizaki, Piero Carninci, Thomas R Gingeras, John S Mattick

Get full text

T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation by Alexandro Landshammer, Adriano Bolondi, Helene Kretzmer, Christian Much, René Buschow, Alina Rose, Hua-Jun Wu, Sebastian D Mackowiak, Bjoern Braendl, Pay Giesselmann, Rosaria Tornisiello, Krishna Mohan Parsi, Jack Huey, Thorsten Mielke, David Meierhofer, René Maehr, Denes Hnisz, Franziska Michor, John L Rinn, Alexander Meissner

Get full text

Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2 by Roland Elling, Elektra K. Robinson, Barbara Shapleigh, Stephen C. Liapis, Sergio Covarrubias, Sol Katzman, Abigail F. Groff, Zhaozhao Jiang, Shiuli Agarwal, Mona Motwani, Jennie Chan, Shruti Sharma, Elizabeth J. Hennessy, Garret A. FitzGerald, Michael T. McManus, John L. Rinn, Katherine A. Fitzgerald, Susan Carpenter

Get full text

The Tug1 lncRNA locus is essential for male fertility by Jordan P. Lewandowski, Gabrijela Dumbović, Audrey R. Watson, Taeyoung Hwang, Emily Jacobs-Palmer, Nydia Chang, Christian Much, Kyle M. Turner, Christopher Kirby, Nimrod D. Rubinstein, Abigail F. Groff, Steve C. Liapis, Chiara Gerhardinger, Assaf Bester, Pier Paolo Pandolfi, John G. Clohessy, Hopi E. Hoekstra, Martin Sauvageau, John L. Rinn

Get full text

lncRNA requirements for mouse acute myeloid leukemia and normal differentiation by M Joaquina Delás, Leah R Sabin, Egor Dolzhenko, Simon RV Knott, Ester Munera Maravilla, Benjamin T Jackson, Sophia A Wild, Tatjana Kovacevic, Eva Maria Stork, Meng Zhou, Nicolas Erard, Emily Lee, David R Kelley, Mareike Roth, Inês AM Barbosa, Johannes Zuber, John L Rinn, Andrew D Smith, Gregory J Hannon

Get full text

Genome-wide binding analysis of 195 DNA binding proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation. by Michael J Smallegan, Soraya Shehata, Savannah F Spradlin, Alison Swearingen, Graycen Wheeler, Arpan Das, Giulia Corbet, Benjamin Nebenfuehr, Daniel Ahrens, Devin Tauber, Shelby Lennon, Kevin Choi, Thao Huynh, Tom Wieser, Kristen Schneider, Michael Bradshaw, Joel Basken, Maria Lai, Timothy Read, Matt Hynes-Grace, Dan Timmons, Jon Demasi, John L Rinn

Get full text