John C. Crabbe

John C. Crabbe, Jr. is an American neuroscientist and behavior geneticist. He is a professor of behavioral neuroscience at the Oregon Health & Science University (OHSU) School of Medicine, where he has worked since 1979. He is also a senior research career scientist at the Veterans Affairs Medical Center in Portland, Oregon. He is also the former director of OHSU's Portland Alcohol Research Center.

Crabbe is known for his research using mouse models to study the pharmacogenetics of alcoholism. He is also known for a 1999 study he and his colleagues published documenting significant variations in certain mouse behaviors across different labs, even when they all tried to follow the same protocols. In 2011, he was chosen by the National Institute on Alcohol Abuse and Alcoholism to give the 16th annual Mark Keller Honorary Lecture.

Crabbe is a member of the editorial board of ''Genes, Brain and Behavior''. Provided by Wikipedia
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  1. 1
    Stable Histone Methylation Changes at Proteoglycan Network Genes Following Ethanol Exposure

    Stable Histone Methylation Changes at Proteoglycan Network Genes Following Ethanol Exposure by David P. Gavin, David P. Gavin, Joel G. Hashimoto, Joel G. Hashimoto, Nathan H. Lazar, Lucia Carbone, John C. Crabbe, John C. Crabbe, Marina Guizzetti, Marina Guizzetti

    Published 2018-08-01
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  2. 2
    Corticosterone Levels and Glucocorticoid Receptor Gene Expression in High Drinking in the Dark Mice and Their Heterogeneous Stock (HS/NPT) Founder Line

    Corticosterone Levels and Glucocorticoid Receptor Gene Expression in High Drinking in the Dark Mice and Their Heterogeneous Stock (HS/NPT) Founder Line by Antonia M. Savarese, Kolter B. Grigsby, Bryan E. Jensen, Bryan E. Jensen, Marissa B. Borrego, Marissa B. Borrego, Deborah A. Finn, Deborah A. Finn, John C. Crabbe, John C. Crabbe, Angela R. Ozburn, Angela R. Ozburn

    Published 2022-05-01
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  3. 3
    Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice

    Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice by Kolter B Grigsby, Antonia M Savarese, Pamela Metten, Barbara J Mason, Yuri A Blednov, John C Crabbe, Angela R Ozburn

    Published 2020-11-01
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  4. 4
    Tetracycline derivatives reduce binge alcohol consumption in High Drinking in the Dark mice

    Tetracycline derivatives reduce binge alcohol consumption in High Drinking in the Dark mice by John C. Crabbe, Angela R. Ozburn, Robert J. Hitzemann, Stephanie E. Spence, Wyatt R. Hack, Jason P. Schlumbohm, Pamela Metten

    Published 2020-04-01
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  5. 5
    Ethanol Conditioned Taste Aversion in High Drinking in the Dark Mice

    Ethanol Conditioned Taste Aversion in High Drinking in the Dark Mice by John C. Crabbe, Pamela Metten, Antonia M. Savarese, Angela R. Ozburn, Jason P. Schlumbohm, Stephanie E. Spence, Wyatt R. Hack

    Published 2019-01-01
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  6. 6
    Ethanol-Related Behaviors in Mouse Lines Selectively Bred for Drinking to Intoxication

    Ethanol-Related Behaviors in Mouse Lines Selectively Bred for Drinking to Intoxication by Bryan E. Jensen, Kayla G. Townsley, Kolter B. Grigsby, Pamela Metten, Meher Chand, Miracle Uzoekwe, Alex Tran, Evan Firsick, Katherine LeBlanc, John C. Crabbe, Angela R. Ozburn

    Published 2021-02-01
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  7. 7
    How should addiction-related research at the National Institutes of Health be reorganized?

    How should addiction-related research at the National Institutes of Health be reorganized? by Bankole A Johnson, Robert eMessing, Michael E Charness, John C. Crabbe, Mark eGoldman, Robert Adron Harris, Henry eKranzler, Mack eMitchell, Sara Jo Nixon, Edward eRiley, Marc eSchuckit, Kenneth eSher, Jennifer eThomas

    Published 2011-05-01
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  8. 8
    Preclinical and clinical evidence for suppression of alcohol intake by apremilast

    Preclinical and clinical evidence for suppression of alcohol intake by apremilast by Kolter B. Grigsby, Regina A. Mangieri, Amanda J. Roberts, Marcelo F. Lopez, Evan J. Firsick, Kayla G. Townsley, Alan Beneze, Jessica Bess, Toby K. Eisenstein, Joseph J. Meissler, John M. Light, Jenny Miller, Susan Quello, Farhad Shadan, Michael Skinner, Heather C. Aziz, Pamela Metten, Richard A. Morrisett, John C. Crabbe, Marisa Roberto, Howard C. Becker, Barbara J. Mason, Angela R. Ozburn

    Published 2023-03-01
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