Showing 1 - 8 results of 8 for search 'John D Klement', query time: 0.04s Refine Results
  1. 1
    H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

    H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells by Priscilla S. Redd, Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Gang Zhou, Takumi Kumai, Esteban Celis, Kebin Liu

    Published 2018-09-01
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  2. 2
    Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes

    Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes by Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Wei Xiao, Priscilla S. Redd, Asha Nayak-Kapoor, Gang Zhou, Kebin Liu

    Published 2019-06-01
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  3. 3
    p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy

    p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy by Jennifer L Waller, David H Munn, Chunwan Lu, Kebin Liu, John D Klement, Alyssa D Smith, Dafeng Yang, Darren D Browning

    Published 2020-10-01
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  4. 4
    IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes

    IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes by Dakota B. Poschel, Mercy Kehinde-Ige, John D. Klement, Dafeng Yang, Alyssa D. Merting, Natasha M. Savage, Huidong Shi, Kebin Liu

    Published 2023-01-01
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  5. 5
    WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

    WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape by Jennifer L Waller, Chunwan Lu, Kebin Liu, John D Klement, Dafeng Yang, Zhuoqi Liu, Alyssa D Merting, Dakota Poschel, Thomas Albers, Huidong Shi

    Published 2021-07-01
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  6. 6
    G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes

    G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes by Chunwan Lu, Kebin Liu, John D Klement, Dafeng Yang, Huidong Shi, Yolonda L Colson, Nicholas H Oberlies, Cedric J Pearce, Aaron H Colby, Mark W Grinstaff, Han-Fei Ding

    Published 2022-01-01
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  7. 7
    Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis

    Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis by Mohammed L. Ibrahim, John D. Klement, Chunwan Lu, Priscilla S. Redd, Wei Xiao, Dafeng Yang, Darren D. Browning, Natasha M. Savage, Phillip J. Buckhaults, Herbert C. Morse, III, Kebin Liu

    Published 2018-12-01
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  8. 8
    PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis

    PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis by Dakota B. Poschel, John D. Klement, Alyssa D. Merting, Chunwan Lu, Yang Zhao, Dafeng Yang, Wei Xiao, Huabin Zhu, Ponnala Rajeshwari, Michael Toscano, Kimya Jones, Amanda Barrett, Roni J. Bollag, Padraic G. Fallon, Huidong Shi, Kebin Liu

    Published 2024-10-01
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