β-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro model. by Lucas M Sjeklocha, Phillip Y-P Wong, John D Belcher, Gregory M Vercellotti, Clifford J Steer

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Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells by Ping Zhang, Julia Nguyen, Fuad Abdulla, Alexander T. Nelson, Joan D. Beckman, Gregory M. Vercellotti, John D. Belcher

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Identification of a Heme Activation Site on the MD-2/TLR4 Complex by John D. Belcher, Ping Zhang, Julia Nguyen, Zachary M. Kiser, Karl A. Nath, Jianjun Hu, John O. Trent, Gregory M. Vercellotti

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Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease by Gregory M Vercellotti, Ping Zhang, Julia Nguyen, Fuad Abdulla, Chunsheng Chen, Phong Nguyen, Carlos Nowotny, Clifford J Steer, Ann Smith, John D Belcher

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Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia. by John D Belcher, Edward Gomperts, Julia Nguyen, Chunsheng Chen, Fuad Abdulla, Zachary M Kiser, David Gallo, Howard Levy, Leo E Otterbein, Gregory M Vercellotti

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The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice. by John D Belcher, Chunsheng Chen, Julia Nguyen, Fuad Abdulla, Phong Nguyen, Minh Nguyen, Nicole M Okeley, Dennis R Benjamin, Peter D Senter, Gregory M Vercellotti

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Erythroid-specific expression of β-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. by Lucas M Sjeklocha, Chang-Won Park, Phillip Y-P Wong, Mark J Roney, John D Belcher, Dan S Kaufman, Gregory M Vercellotti, Robert P Hebbel, Clifford J Steer

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Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease by Joan D. Beckman, Fuad Abdullah, Chunsheng Chen, Rachel Kirchner, Dormarie Rivera-Rodriguez, Zachary M. Kiser, Aithanh Nguyen, Ping Zhang, Julia Nguyen, Robert P. Hebbel, John D. Belcher, Gregory M. Vercellotti

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Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction. by John D Belcher, Chunsheng Chen, Julia Nguyen, Fuad Abdulla, Ping Zhang, Hao Nguyen, Phong Nguyen, Trevor Killeen, Sylvia M Miescher, Nathan Brinkman, Karl A Nath, Clifford J Steer, Gregory M Vercellotti

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H-Ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice by Gregory M Vercellotti, Fatima B Khan, Heather eBechtel, Karl A Nath, Julia eNguyen, Chunseng eChen, Carol M Bruzzone, Graham eBrown, Clifford John Steer, Robert P Hebbel, John D. Belcher

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The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease by John D. Belcher, Selvaraj Nataraja, Fuad Abdulla, Ping Zhang, Chunsheng Chen, Julia Nguyen, Conglin Ruan, Maneet Singh, Shilpa Demes, Lyndsay Olson, Domi Stickens, Jeff Stanwix, Emer Clarke, Yongzhao Huang, Margaret Biddle, Gregory M. Vercellotti

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Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence by Thomas Gentinetta, John D. Belcher, Valérie Brügger-Verdon, Jacqueline Adam, Tanja Ruthsatz, Joseph Bain, Daniel Schu, Lisa Ventrici, Monika Edler, Hadi Lioe, Kalpeshkumar Patel, Chunsheng Chen, Julia Nguyen, Fuad Abdulla, Ping Zhang, Andreas Wassmer, Meena Jain, Marcel Mischnik, Matthias Pelzing, Kirstee Martin, Roslyn Davis, Svetlana Didichenko, Alexander Schaub, Nathan Brinkman, Eva Herzog, Adrian Zürcher, Gregory M. Vercellotti, Gregory J. Kato, Gerald Höbarth

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