Genomic Alterations and Their Implications on Survival in Nonmetastatic Colorectal Cancer: Status Quo and Future Perspectives by Reetu Mukherji, John L. Marshall, Andreas Seeber

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Significance and implications of FDA approval of pembrolizumab for biomarker-defined disease by Michael M. Boyiadzis, John M. Kirkwood, John L. Marshall, Colin C. Pritchard, Nilofer S. Azad, James L. Gulley

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Recurrence of early stage colon cancer predicted by expression pattern of circulating microRNAs. by Narayan Shivapurkar, Louis M Weiner, John L Marshall, Subha Madhavan, Anne Deslattes Mays, Hartmut Juhl, Anton Wellstein

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Correction: Recurrence of Early Stage Colon Cancer Predicted by Expression Pattern of Circulating microRNAs. by Narayan Shivapurkar, Louis M. Weiner, John L. Marshall, Subha Madhavan, Anne Deslattes Mays, Hartmut Juhl, Anton Wellstein

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The current state of molecular profiling in gastrointestinal malignancies by Reetu Mukherji, Chao Yin, Rumaisa Hameed, Ali Z. Alqahtani, Monika Kulasekaran, Aiwu R. He, Benjamin A. Weinberg, John L. Marshall, Marion L. Hartley, Marcus S. Noel

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A phase I trial of the mTOR inhibitor temsirolimus in combination with capecitabine in patients with advanced malignancies by Neel D. Trivedi, Samantha Armstrong, Hongkun Wang, Marion Hartley, John Deeken, A. Ruth He, Deepa Subramaniam, Heather Melville, Chris Albanese, John L. Marshall, Jimmy Hwang, Michael J. Pishvaian

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Pan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes by Andrew Elliott, Michelle Saul, Jia Zeng, John L. Marshall, Edward S. Kim, Misako Nagasaka, Heinz-Josef Lenz, Lee Schwartzberg, David Spetzler, Jim Abraham, Joanne Xiu, Phillip Stafford, W. Michael Korn

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<i>WRN</i>-Mutated Colorectal Cancer Is Characterized by a Distinct Genetic Phenotype by Kai Zimmer, Alberto Puccini, Joanne Xiu, Yasmine Baca, Gilbert Spizzo, Heinz-Josef Lenz, Francesca Battaglin, Richard M. Goldberg, Axel Grothey, Anthony F. Shields, Mohamed E. Salem, John L. Marshall, W. Michael Korn, Dominik Wolf, Florian Kocher, Andreas Seeber

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Propagated Circulating Tumor Cells Uncover the Potential Role of NFκB, EMT, and TGFβ Signaling Pathways and <i>COP1</i> in Metastasis by Jerry Xiao, Utsav Sharma, Abolfazl Arab, Sohit Miglani, Sonakshi Bhalla, Shravanthy Suguru, Robert Suter, Reetu Mukherji, Marc E. Lippman, Paula R. Pohlmann, Jay C. Zeck, John L. Marshall, Benjamin A. Weinberg, Aiwu Ruth He, Marcus S. Noel, Richard Schlegel, Hani Goodarzi, Seema Agarwal

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Molecular profile of BRCA-mutated biliary tract cancers by Michael Hall, Arno Amann, Joanne Xiu, Alberto Puccini, Francesca Battaglin, Heinz-Josef Lenz, Mohamed E Salem, Gilbert Spizzo, Richard M Goldberg, Axel Grothey, Anthony F Shields, Sukeshi Patel Arora, Yasmine Baca, Wafik S El-Deiry, Philip A Philip, Madiha Nassem, John L Marshall, Florian Kocher, Dominik Wolf, W Michael Korn, Andreas Seeber, Moh’d Khushman

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Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients by Alberto Puccini, Andreas Seeber, Joanne Xiu, Richard M. Goldberg, Davide Soldato, Axel Grothey, Anthony F. Shields, Mohamed E. Salem, Francesca Battaglin, Martin D. Berger, Wafik S. El-Deiry, Ryuma Tokunaga, Madiha Naseem, Wu Zhang, Sukeshi Patel Arora, Moh’d M. Khushman, Michael J. Hall, Philip A. Philip, John L. Marshall, W. Michael Korn, Heinz-Josef Lenz

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Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes by Valeriy Domenyuk, Zoran Gatalica, Radhika Santhanam, Xixi Wei, Adam Stark, Patrick Kennedy, Brandon Toussaint, Symon Levenberg, Jie Wang, Nianqing Xiao, Richard Greil, Gabriel Rinnerthaler, Simon P. Gampenrieder, Amy B. Heimberger, Donald A. Berry, Anna Barker, John Quackenbush, John L. Marshall, George Poste, Jeffrey L. Vacirca, Gregory A. Vidal, Lee S. Schwartzberg, David D. Halbert, Andreas Voss, Daniel Magee, Mark R. Miglarese, Michael Famulok, Günter Mayer, David Spetzler

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CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value by Yan Yang, Fang-Shu Ou, Emil Lou, Joanne Xiu, Hiroyuki Arai, Francesca Battaglin, Heinz-Josef Lenz, Richard M Goldberg, Anthony F Shields, Yasmine Baca, Philip A Philip, John L Marshall, W Michael Korn, Andreas Seeber, Natsuko Kawanishi, Jingyuan Wang, Shivani Soni, Wu Zhang, Shannon M Mumenthaler, Joshua Millstein, Priya Jayachandran, Federico Innocenti, Annika Lenz, Sandra Algaze, Taline Khoukaz, Evanthia Roussos Torres, Jim P Abraham, Benjamin A Weinberg, Alan P Venook

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PBRM1 mutations might render a subtype of biliary tract cancers sensitive to drugs targeting the DNA damage repair system by Kai Zimmer, Florian Kocher, Gerold Untergasser, Brigitte Kircher, Arno Amann, Yasmine Baca, Joanne Xiu, W. Micheal Korn, Martin D. Berger, Heinz-Josef Lenz, Alberto Puccini, Elisa Fontana, Anthony F. Shields, John L. Marshall, Michael Hall, Wafik S. El-Deiry, David Hsiehchen, Teresa Macarulla, Josep Tabernero, Renate Pichler, Moh’d Khushman, Upender Manne, Emil Lou, Dominik Wolf, Viktorija Sokolova, Simon Schnaiter, Alain G. Zeimet, Pat Gulhati, Gerlig Widmann, Andreas Seeber

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