An evaluation of factors that may influence clinicians' decisions not to enroll eligible patients into randomized trials in critical care. by Mahesh Ramanan, Laurent Billot, Dorrilyn Rajbhandari, John Myburgh, Balasubramanian Venkatesh

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Does asymmetry in patient recruitment in large critical care trials follow the Pareto principle? by Mahesh Ramanan, Laurent Billot, Dorrilyn Rajbhandari, John Myburgh, Simon Finfer, Rinaldo Bellomo, Balasubramanian Venkatesh

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The Effect of Paracetamol on Core Body Temperature in Acute Traumatic Brain Injury: A Randomised, Controlled Clinical Trial. by Manoj K Saxena, Colman Taylor, Laurent Billot, Severine Bompoint, John Gowardman, Jason A Roberts, Jeffery Lipman, John Myburgh

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A Novel Risk Prediction Model for Severe Acute Kidney Injury in Intensive Care Unit Patients Receiving Fluid Resuscitation by Yunlin Feng, Yunlin Feng, Qiang Li, Simon Finfer, John Myburgh, Rinaldo Bellomo, Vlado Perkovic, Meg Jardine, Meg Jardine, Amanda Y. Wang, Amanda Y. Wang, Martin Gallagher, Martin Gallagher

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Use of selective gut decontamination in critically ill children: PICnIC a pilot RCT and mixed-methods study by Alanna Brown, Paloma Ferrando-Vivas, Mariana Popa, Gema Milla de la Fuente, John Pappachan, Brian H Cuthbertson, Laura Drikite, Richard Feltbower, Theodore Gouliouris, Isobel Sale, Robert Shulman, Lyvonne N Tume, John Myburgh, Kerry Woolfall, David A Harrison, Paul R Mouncey, Kathryn Rowan, Nazima Pathan

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Selective digestive tract decontamination to prevent healthcare associated infections in critically ill children: the PICNIC multicentre randomised pilot clinical trial by Nazima Pathan, Kerry Woolfall, Mariana Popa, Gema Milla de la Fuente, Paloma Ferrando-Vivas, Alanna Brown, Theodore Gouliouris, Lyvonne N. Tume, Robert Shulman, Brian H. Cuthbertson, Isobel Sale, Richard G. Feltbower, John Myburgh, John Pappachan, David Harrison, Paul Mouncey, Kathryn Rowan, the PICNIC study investigators

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Proton pump inhibitors in critically ill mechanically ventilated patients with COVID-19: protocol for a substudy of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Tri... by Brittany B. Dennis, Lehana Thabane, Diane Heels-Ansdell, Joanna C. Dionne, Alexandra Binnie, Jennifer Tsang, Gordon Guyatt, Aijaz Ahmed, François Lauzier, Adam Deane, Yaseen Arabi, John Marshall, Nicole Zytaruk, Lois Saunders, Simon Finfer, John Myburgh, John Muscedere, Shane English, Marlies Ostermann, Miranda Hardie, Serena Knowles, Deborah Cook, For the REVISE Investigators the Canadian Critical Care Trials Group

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REVISE: re-evaluating the inhibition of stress erosions in the ICU—statistical analysis plan for a randomized trial by Diane Heels-Ansdell, Laurent Billot, Lehana Thabane, Waleed Alhazzani, Adam Deane, Gordon Guyatt, Simon Finfer, François Lauzier, John Myburgh, Paul Young, Yaseen Arabi, John Marshall, Shane English, John Muscedere, Marlies Ostermann, Bala Venkatesh, Nicole Zytaruk, Miranda Hardie, Naomi Hammond, Serena Knowles, Lois Saunders, Alexis Poole, Abdulrahman Al-Fares, Feng Xie, Richard Hall, Deborah Cook

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Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study. by Naomi E Hammond, Colman Taylor, Simon Finfer, Flavia R Machado, YouZhong An, Laurent Billot, Frank Bloos, Fernando Bozza, Alexandre Biasi Cavalcanti, Maryam Correa, Bin Du, Peter B Hjortrup, Yang Li, Lauralyn McIntryre, Manoj Saxena, Frédérique Schortgen, Nicola R Watts, John Myburgh, Fluid-TRIPS and Fluidos Investigators, George Institute for Global Health, The ANZICS Clinical Trials Group, BRICNet, and the REVA research Network

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A Genome-Wide Association Study of Serum Metabolite Profiles in Septic Shock Patients by Emily R. Daubney, BE/BSc, Shannon D’Urso, BAdvSc (Hons), Gabriel Cuellar-Partida, PhD, Dorrilyn Rajbhandari, RN, Elizabeth Peach, MS, Erika de Guzman, BBSc, Colin McArthur, MD, Andrew Rhodes, MD, Jason Meyer, RN, Simon Finfer, MD, John Myburgh, MD, PhD, Jeremy Cohen, MD, PhD, Horst Joachim Schirra, PhD, Balasubramanian Venkatesh, MD, David M. Evans, PhD

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REVISE: Re-Evaluating the Inhibition of Stress Erosions in the ICU: a randomised trial protocol by Lehana Thabane, Gordon Guyatt, Diane Heels-Ansdell, Deborah J Cook, Yaseen Arabi, John Muscedere, Paul Young, Feng Xie, François Lauzier, Laurent Billot, Waleed Alhazzani, Marlies Ostermann, Shane English, Daniel Johnson, John C Marshall, Nicole Zytaruk, Balasubramanian Venkatesh, Simon Finfer, John Myburgh, R Hall, Mobeen Iqbal, Abdulrahman A Al-Fares, Gilmar Reis, Alexis Poole, Adam M Deane, Marianne J Chapman, Dorrilyn Rajbhandari, Naomi E Hammond, Serena Knowles, Miranda Hardie, Lois Saunders

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